research Distinct transcriptomic landscapes of cutaneous basal cell carcinomas and squamous cell carcinomas
Basal cell carcinomas and squamous cell carcinomas have different gene activity patterns, suggesting unique treatment approaches.
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870-900 / 1000+ resultsresearch Medium-molecular weight hyaluronic acid orchestrates hair follicle regeneration via CD44/AKT-driven endogenous ROS activation of β-catenin
research Jagged-1+ Skin Tregs Modulate the Innate Immune Response to Wound Healing
Jagged-1 in skin Tregs is crucial for timely wound healing by recruiting specific immune cells.
research Androgen receptor transactivity is potentiated by TGF-β1 through Smad3 but checked by its coactivator Hic-5/ARA55 in balding dermal papilla cells
TGF-β1 increases androgen receptor activity in hair loss, but Hic-5/ARA55 can counter this effect.
research Major Differences in Expression of Inflammatory Pathways in Skin from Different Body Sites of Healthy Individuals
Different parts of the body have unique immune characteristics in their skin.
research 174 Dermis-hair follicle communication: Extracellular microvesicles signaling for hair regeneration
Tiny particles from skin cells can help activate hair growth.
research Analysis on the maintenance mechanisms of human interfollicular epidermal stem cell and their niche
Epidermal stem cells use integrin β1 and α6 as markers and CD271+ cells help maintain skin health and heal wounds.
research Common Skin Diseases and Metabolic Syndrome: A Proinflammatory Chemokine Perspective
Chronic skin diseases and metabolic syndrome are linked by shared inflammation pathways.
research Calcineurin/Nfatc1 signaling links skin stem cell quiescence to hormonal signaling during pregnancy and lactation
Hormones during pregnancy and lactation keep skin stem cells inactive, preventing hair growth.
research Nutrients regulation of skin cells from canines and cats via Wnt/β-catenin signaling pathway
Certain nutrients like keratin, egg yolk, and fish collagen may help pets regrow hair.
research Single‐cell transcriptomics reveals a senescence‐associated IL ‐6/ CCR6 axis driving radiodermatitis
Blocking certain immune signals can reduce skin damage from radiation therapy.
research Role of regeneration in tissue repairing and therapies
The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.
research Careless talk costs lives: fibroblast growth factor receptor signalling and the consequences of pathway malfunction
Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.
research [Expressions and effects of autophagy-related genes in bleomycin-induced skin fibrosis of mice].
Activating autophagy might reverse skin fibrosis.
research Knockout of integrin β1 in induced pluripotent stem cells accelerates skin-wound healing by promoting cell migration in extracellular matrix
Turning off a specific gene in stem cells speeds up skin healing by helping cells move better.
research Off-label use of biologics and janus kinase (JAK) inhibitors for scarring alopecias: a narrative review
Biologics and JAK inhibitors may improve treatment for scarring alopecias.
research Self-Organizing 3D Dermal Papilla Cell Spheroids Yield Therapeutic Extracellular Vesicles that Target Hypertrophic Scar Regression via the miR-26a-5p/CCNE2 Axis
3D cell spheroids can help reduce scars by delivering therapeutic vesicles.
research Role of -catenin in Epidermal Stem Cell Expansion, Lineage Selection, and Cancer
Beta-catenin is crucial for skin cell growth, development, and cancer formation.
research Immunological control of skin development: from homeostasis to developmental pathologies
Immune cells are crucial for normal skin development and their dysfunction can cause skin disorders.
research Targeting the Hippo/YAP /TAZ signalling pathway: Novel opportunities for therapeutic interventions into skin cancers
Blocking YAP/TAZ could be a new way to treat skin cancer.
research 609 Symmetry breaking of tissue mechanics in wound induced hair follicle regeneration
Activating TRPA1 reduces scarring and promotes tissue regeneration.
research Effects of mesenchymal stem cell therapy on alopecia areata in cellular and hair follicle organ culture models
Mesenchymal stem cell therapy may help treat alopecia areata by promoting hair growth and reducing inflammation.
research Signaling in the stem cell niche: regulating cell fate, function and plasticity
The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.
research Multi-modal skin atlas identifies a multicellular immune-stromal community associated with disrupted cornification and specific T cell expansion in atopic dermatitis
A specific group of immune and skin cells may cause chronic inflammation in atopic dermatitis.
research From rare hypertrichosis to common alopecia: new pathways for hair regeneration
research 0846 Wnt signaling drives hair follicle regeneration in wounds by attenuating mechanotransduction in the epidermis
Wnt signaling helps regenerate hair follicles in wounds by reducing skin cell sensitivity to mechanical stress.
research A preliminary study of differentially expressed genes in expanded skin and normal skin: implications for adult skin regeneration
The study found that expanded skin regenerates similarly to normal skin, with 77 genes playing a role in the process.
research Commensal Microbes and Hair Follicle Morphogenesis Coordinately Drive Treg Migration into Neonatal Skin
Hair follicle development and microbes help regulatory T cells gather in newborn skin.
research Systems for Mitochondria-Protective Cosmetic Actives: Opportunities in Post-Oncologic Skin Regeneration
Nanocarriers can improve skin treatments after cancer therapy by enhancing antioxidant delivery and effectiveness.
research 965 The importance of CD206+ macrophages in squaric acid dibutylester-induced hair cycle activation
CD206+ macrophages are crucial for hair growth in alopecia areata treatment.