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research In Human Skin, UVB Initiates Early Induction of IL-10 Over IL-12 Preferentially in the Expanding Dermal Monocytic/Macrophagic Population

101 citations , July 1998 in “Journal of Investigative Dermatology”

UVB exposure in human skin causes macrophages to produce more IL-10 and less IL-12, leading to immunosuppression.

Clinical and Dermoscopic Evaluation of the Safety and Efficacy of Oral Baricitinib (JAK Inhibitor) in Treatment of Localized Vitiligo Either Alone or with Topical Tacrolimus

research Clinical and Dermoscopic Evaluation of the Safety and Efficacy of Oral baricitinib (JAK Inhibitor) in Treatment of Localized Vitiligo Either Alone or with Topical Tacrolimus

January 2025 in “The Egyptian Journal of Hospital Medicine”

Baricitinib is effective and safe for treating localized vitiligo, alone or with topical tacrolimus.

research Chitinase 3-Like 1 and C-X-C motif chemokine ligand 5 proteins and the hair cycle

August 2024 in “Archives of Dermatological Research”

CHI3L1 and CXCL5 proteins help promote hair growth.

research YAP/TAZ Signalling Controls Epidermal Keratinocyte Fate

14 citations , November 2024 in “International Journal of Molecular Sciences”

YAP and TAZ proteins control skin cell growth and repair.

research Improvement of Recalcitrant Dissecting Cellulitis of the Scalp After a Trial of Upadacitinib

1 citations , January 2024 in “Curēus”

Upadacitinib significantly improved a man's severe scalp condition when other treatments failed.

research 0955 Selective BET inhibition as potential hidradenitis suppurativa treatment

July 2025 in “Journal of Investigative Dermatology”

research Targeted Overexpression of the Angiogenesis Inhibitor Thrombospondin-1 in the Epidermis of Transgenic Mice Prevents Ultraviolet-B-Induced Angiogenesis and Cutaneous Photo-Damage

93 citations , May 2002 in “Journal of Investigative Dermatology”

Overexpressing thrombospondin-1 in mice skin prevents UVB-induced skin damage.

research Potassium channel openers: therapeutic potential in cardiology and medicine

25 citations , December 2001 in “Expert Opinion on Pharmacotherapy”

Potassium channel openers show promise for treating heart disease and other conditions, but more research is needed to fully understand their effects and safety.

Minoxidil Exerts Different Inhibitory Effects on Gene Expression of Lysyl Hydroxylase 1, 2, and 3: Implications for Collagen Cross-Linking and Treatment of Fibrosis

research Minoxidil exerts different inhibitory effects on gene expression of lysyl hydroxylase 1, 2, and 3: Implications for collagen cross-linking and treatment of fibrosis

38 citations , June 2005 in “Matrix Biology”

Minoxidil affects collagen-related genes, potentially helping treat fibrosis.

research Modulation der Hitzesensitivität im Prostatakarzinom in vitro: Der Einfluss der Androgenachse

January 2022

Androgen-modulating drugs do not significantly change the heat sensitivity of prostate cancer cells.

research Analysis of Sequences Controlling Tissue-Specific and Hyperproliferation-Related Keratin 6 Gene Expression in Transgenic Mice

26 citations , February 1998 in “DNA and Cell Biology”

K6 gene expression can be controlled and manipulated in mice for studying skin disorders.

research Severe follicular hyperplasia and spontaneous papilloma formation in transgenic mice expressing theneu oncogene under the control of the bovine keratin 5 promoter

47 citations , January 1998 in “Molecular Carcinogenesis”

ErbB2 signaling is crucial for skin cell growth and cancer development in mice.

Compartmentalized Epidermal Activation of β-Catenin Differentially Affects Lineage Reprogramming and Underlies Tumor Heterogeneity

research Compartmentalized Epidermal Activation of β-Catenin Differentially Affects Lineage Reprogramming and Underlies Tumor Heterogeneity

54 citations , January 2016 in “Cell reports”

Activating β-catenin in different skin stem cells causes various types of hair growth and skin tumors.

research A Case of Alopecia Totalis with Lichen Planus Hypertrophicus Responded Excellently to Oral Tofacitinib-An Observation

2 citations , February 2024 in “Indian Dermatology Online Journal”

research Assessment of Dysregulation of HERC6 and Essential Biological Processes in Response to Laser Therapy of Human Arm Skin

March 2020 in “Journal of lasers in medical sciences”

Laser therapy on human skin affects the HERC6 gene and related genes, influencing many cell processes and requiring careful safety measures.

research Medium-molecular weight hyaluronic acid orchestrates hair follicle regeneration via CD44/AKT-driven endogenous ROS activation of β-catenin

April 2026 in “International Journal of Biological Macromolecules”

research BI02 (P97): Epidermal growth factor receptor inhibitor therapy induces a distinct inflammatory hair follicle response that includes a collapse of immune privilege

July 2022 in “British Journal of Dermatology”

research Foxn1 in Skin Development, Homeostasis and Wound Healing

21 citations , July 2018 in “International Journal of Molecular Sciences”

Foxn1 is crucial for skin development and healing, and altering its expression may aid regenerative medicine.

research Identification of drug-specific public TCR driving severe cutaneous adverse reactions

88 citations , August 2019 in “Nature communications”

Researchers found a specific immune receptor in patients that causes severe skin reactions to a drug.

research Quiescent and aging hair follicle stem cells

February 2016 in “Science”

Foxc1 and COL17A1 are crucial for maintaining healthy hair follicles and preventing hair loss.

research 090 Stromal re-organization in hair follicle development and cancer suppression

April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology”

Activating Sonic Hedgehog signaling in cancer stroma may help treat basal cell carcinoma.

research miR-200a Targets PITX2 to Mediate Goose Fibroblast Proliferation Through the Wnt Pathway

October 2025 in “Animals”

miR-200a reduces goose fibroblast growth by targeting PITX2 in the Wnt pathway.

research Inhibition of the CoREST Repressor Complex Promotes Wound Re-Epithelialization through the Regulation of Keratinocyte Migration

8 citations , August 2023 in “Journal of Investigative Dermatology”

research Msx2 Prevents Stratified Squamous Epithelium Formation in the Enamel Organ

18 citations , June 2018 in “Journal of Dental Research”

Msx2 is essential for proper enamel formation by preventing abnormal cell transformation.

research Co‐regulatory mechanisms and potential markers of oxidative stress‐related genes in vitiligo and alopecia areata

5 citations , August 2024 in “Skin Research and Technology”

KLB and EIF3C genes are key for early diagnosis of vitiligo and alopecia areata.

research TAZ enhances the activity of the AKT signaling pathway to promote adipogenesis of gADSCs

September 2025 in “Stem Cell Research & Therapy”

TAZ boosts fat cell formation in goat stem cells by activating a specific signaling pathway.

research Lgr5+ stem cells and their progeny in mouse epidermis under regimens of exogenous skin carcinogenesis, and their absence in ensuing skin tumors

8 citations , July 2016 in “Oncotarget”

Lgr5+ stem cells do not cause skin tumors.

research miR-133a-3p and miR-145-5p co-promote goat hair follicle stem cell differentiation by regulating NANOG and SOX9 expression

November 2023 in “Animal Bioscience”

miR-133a-3p and miR-145-5p help goat hair follicle stem cells differentiate by controlling NANOG and SOX9.

research From Hair to Colon: Hair Follicle-Derived MSCs Alleviate Pyroptosis in DSS-Induced Ulcerative Colitis by Releasing Exosomes in a Paracrine Manner

1 citations , January 2022 in “Oxidative Medicine and Cellular Longevity”

Hair follicle stem cells can help treat ulcerative colitis in mice by releasing beneficial exosomes.

research The cellular basis of mechanosensory Merkel-cell innervation during development

32 citations , February 2019 in “eLife”

BMP signaling is essential for the development of touch domes.

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