research Morphogenesis of chimeric hair follicles in engineered skin substitutes with human keratinocytes and murine dermal papilla cells
Engineered skin can grow chimeric hair follicles only with mouse dermal papilla cells.
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750-780 / 1000+ resultsresearch Distribution of caspase‐14 in epidermis and hair follicles is evolutionarily conserved among mammals
Caspase-14 is important for skin and hair development in all mammals.
research Dermal papilla-induced hair differentiation of adult epithelial stem cells from human skin
Dermal papilla cells help skin stem cells grow into hair.
research Markers to Evaluate the Quality and Self-Renewing Potential of Engineered Human Skin Substitutes In Vitro and after Transplantation
Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.
research Onset of Keratin 17 Expression Coincides with the Definition of Major Epithelial Lineages during Skin Development
Keratin 17 is important for skin development and may help define skin cell types.
research Cultured Keratinocyte Sheets Enhanced Spontaneous Re-Epithelialization in a Dermal Explant Model of Partial-Thickness Wound Healing
research Chapter 3 Expression and Modification of Keratins During Terminal Differentiation of Mammalian Epidermis
Keratins change and are modified differently in skin layers and body parts.
research Biochemistry of epidermal stem cells
The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.
research Animal models of human skin disease
Mutations in certain skin proteins cause severe skin issues, while others have limited effects, highlighting the need to understand these proteins for better treatments.
research Structural features and sites of expression of a new murine 65 kD and 48 kD hair-related keratin pair, associated with a special type of parakeratotic epithelial differentiation
A new pair of mouse keratins, 65 kD and 48 kD, are found in specific skin areas and are linked to a unique skin differentiation type.
research Differention of ES cell-derived epidermal stem cells in full thickness skin defects
ES cell-derived stem cells can help regenerate skin and form gland-like structures.
research All Roads Go to the Nucleus: Integration of Signaling/Transcription Factor-Mediated and Epigenetic Regulatory Mechanisms in the Control of Skin Development and Regeneration
The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.
research Clinical Snippets
Skin has a larger surface area than thought, certain skin cells improve skin flap survival, better trials for skin conditions in children are needed, Stevens-Johnson syndrome rates vary by age and race, and better skin barrier function may reduce inflammation in the elderly.
research Involucrin: A Constituent of Cross-Linked Envelopes and Marker of Squamous Maturation
Involucrin is crucial for skin cell maturation and protection.
research Immunological aspects of psychodermatology
The skin plays a key role in immune responses and reflects emotional and stress reactions.
research Abstract 5020: Characterization of epidermal stem cells in SKH1 hairless mice, a widely used mouse model to investigate ultraviolet radiation carcinogenesis.
SKH1 hairless mice have identifiable epidermal stem cells with specific markers.
research Interfollicular epidermal stem-like cells for the recreation of the hair follicle epithelial compartment
Human skin cells with stem-like features can help create new hair follicles and sebaceous glands when combined with other cells.
research 859 Building a functional niche for hair follicle stem cells
Deleting the CRIF1 gene in mice disrupts skin and hair formation, certain proteins affect hair growth, a new compound may improve skin and hair health, blood cell-derived stem cells can create skin-like structures, and hair follicle stem cells come from embryonic cells needing specific signals for development.
research Epidermal growth factor and transferrin receptor expression in human embryonic and fetal epidermal cells
research Dermal papilla cells induce keratinocyte tubulogenesis in culture
Skin cells can help create early hair-like structures in lab cultures.
research Differential epithelial outgrowth of plucked and microdissected human hair follicles in explant culture
research Differential epithelial outgrowth of plucked and microdissected human hair follicles in explant culture
research Homeostasis, regeneration and tumour formation in the mammalian epidermis
Stem cells in the skin help with healing and can also lead to cancer.
research Effect of thyroid hormone and epidermal growth factor on tactile hair development and craniofacial morphogenesis in the postnatal rat.
Thyroid hormone and epidermal growth factor affect hair angle, tooth eruption, and ear development in rats.
research 252 Follicle dermal papilla cells undergo chromatin remodelling processes in vivo and in vitro
Hair follicle cells change their DNA packaging during growth cycles and when grown in the lab.
research remarks on the evolution of the integumental scale armour
Pangolin scales evolved for protection, hardening with age, due to keratin gene diversification.
research Hair follicle epithelial stem cells contribute to interfollicular epidermis during homeostasis
Hair follicle stem cells help maintain skin health by moving to and supporting the skin's surface layers.
research Expression of Basement Membrane Proteins and Interstitial Collagens in Dermal Papillae of Human Hair Follicles
research In-vivo dedifferentiation of keratinocytes to epidermal stem cells
Keratinocytes might turn into stem cells, but more research is needed to confirm this.
research Expression of CD1d in human scalp skin and hair follicles: hair cycle related alterations
CD1d expression in scalp skin and hair follicles changes with the hair cycle and may help protect against microbes.