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February 2022 in “The journal of neuroscience/The Journal of neuroscience” Deleting the PTEN gene in mice causes nerve cells to grow larger and heal better after injury, but may cause overgrowth and hair loss in older mice.
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August 2018 in “International Journal of Cosmetic Science” Dermal Papilla cells are a promising tool for evaluating hair growth treatments.
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May 2014 in “BioEssays” Using neurohormones to control keratin can lead to new skin disease treatments.
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July 2019 in “Journal of Cellular Biochemistry” Wnt7a protein is crucial for development and tissue maintenance and plays varying roles in diseases and potential treatments.
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April 2016 in “PloS one” The KRTAP11-1 gene promoter is crucial for specific expression in sheep wool cortex.
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January 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Mice lacking Insig proteins had hair growth problems due to cholesterol buildup, but this was fixed by the drug simvastatin.
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September 2022 in “Viruses” SARS-CoV-2 proteins help the virus avoid the immune system, delaying response and increasing inflammation.
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January 2023 in “Proteomes” Tumor proteins can both promote and suppress cancer, depending on the situation.
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October 2025 in “Cancer” PROTACs offer a new, precise way to treat cancer by breaking down harmful proteins.
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October 2019 in “Frontiers in Immunology” Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.
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January 2006 in “Frontiers in bioscience” CRH in the skin acts like the body's stress response system, affecting cell behavior and immune activity.
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March 2023 in “Journal of Cosmetic Dermatology” Plantago asiatica L. extract can promote hair growth by enhancing the anagen phase.
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January 2016 in “Evidence-based Complementary and Alternative Medicine” Rice bran extract can increase melanin production and may help treat melanin deficiency.
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January 2026 in “Journal of Dermatological Science” Salvianolic acid B promotes hair growth better than minoxidil.
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November 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” Wnt/β-catenin signaling is important for keeping skin cell attachment structures stable.
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February 2025 in “Pharmaceuticals” Voglibose may help treat skin hyperpigmentation safely.
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August 2022 in “International journal of molecular sciences” α-Phellandrene may help prevent hair loss by increasing growth factors and cell growth in hair cells through a specific signaling pathway.
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June 2023 in “Cell Reports” IL-1 promotes fat cell growth in skin, while WNT inhibits it and encourages scar formation.
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June 2024 in “Nutrients” Natural antioxidants like flavonoids and resveratrol may help prevent low testosterone in aging men.
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February 2023 in “Cosmetics” Nostoc verrucosum extracts may help reduce melanin production and have antioxidant properties.
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April 2015 in “InTech eBooks” RAGE is a potential target for melanoma treatment, but its effectiveness is uncertain due to variable expression levels.
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April 2018 in “Journal of Investigative Dermatology” Intralesional chemotherapy with 5-fluorouracil and methotrexate may worsen keratoacanthoma-type skin cancer in transplant patients.