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Tofacitinib effectively treated a woman's complex autoimmune and autoinflammatory disorders.

Neuroactive steroids affect cocaine's rewarding effects through the sigma1 receptor.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

Using computers to analyze drugs can find new uses for them, but actual experiments are needed to confirm these uses.

Epristeride's metabolism involves key metabolites and proteins, affecting its use in doping tests.

New compounds similar to cromakalim were less effective at inhibiting insulin release but improved in solubility and one acted as a calcium entry blocker, not a potassium channel opener.

A new test helps find drugs to treat head and neck cancer by targeting c-Rel.

Finasteride reduces AML cell growth by inhibiting androgen receptors.

Hydroxypinacolone retinoate is a potent anti-aging ingredient for skin that is more effective and less irritating than other forms of retinoids.

LDL apheresis lowers inflammation and cardiovascular risk by reducing CRP levels long-term.

Cepharanthine shows promise as a natural anticancer treatment.

5-alpha reductase inhibitors slightly increase depression risk, but the risk varies based on the control group used.

Some prostate cancers have gene changes that may affect treatment with certain drugs.

RXR agonists may promote hair growth in humans.

Different ligands change the shape of the TRPV3 ion channel in unique ways.

Certain drugs can reduce bladder muscle contractions, potentially helping treat bladder diseases.

Finasteride effectively blocks rat enzymes, but with varying methods and strength.

CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.

Researchers found a specific immune receptor in patients that causes severe skin reactions to a drug.

The research identified and described a gene important for hormone conversion in endangered catfish, which varies in activity during different reproductive stages and after hormone treatment.

Flutamide and CPA are more effective than finasteride for treating acne in hyperandrogenic women.

2-Hydroxy-1,4-naphthoquinone is a strong 5α-reductase inhibitor.

Cedrol may be an effective treatment for colorectal cancer.

A specific gene mutation causes vitamin D resistance, but certain vitamin D analogs might help.

Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.

Rizatriptan benzoate-loaded dissolving microneedles are effective and convenient for treating acute migraines.

Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.

ExoFlo is safe and effective for treating Complex Regional Pain Syndrome symptoms.

Five FDA-approved drugs may help block COVID-19 virus entry.