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High-content screening is useful for finding new treatments for rare diseases and has led to FDA-approved drugs.

Enteral supplements can improve symptoms of Cronkhite-Canada syndrome.

Obese and non-obese women with PCOS have higher heart risk markers, especially if they are obese.

Skin symptoms like fragile skin and easy bruising can indicate Cushing's syndrome, which requires early diagnosis and treatment to prevent serious health issues.

A new genetic mutation in mice causes permanent hair loss and skin wrinkling.

Children with classic congenital adrenal hyperplasia have thicker heart fat and more heart and blood vessel risk factors, especially if their condition is not well-controlled.

All five human steroid 5α-reductase enzymes are found in the endoplasmic reticulum.

Oestrogen and thyrotropin-releasing hormone affect prolactin and its receptor in human skin and hair, suggesting new treatment options for related conditions.

Dual TCR Treg cells are common in various mouse tissues and show diverse characteristics.

Overexpression of hurpin in mice leads to abnormal skin and higher skin cancer risk.

Certain defective glucocorticoid receptor mutants move faster inside cell nuclei and work less effectively.

Overexpression of the glucocorticoid receptor in mice causes developmental defects similar to ectodermal dysplasia.

BRG1 is essential for skin cells to move and heal wounds properly.

Children with classic congenital adrenal hyperplasia have thicker heart fat and are at higher risk for heart problems and early atherosclerosis.

A 78-year-old man with Cronkhite-Canada syndrome improved significantly after treatment and remains symptom-free.

CRET therapy affects inflammation in skin cells by changing cytokine levels and activating certain proteins.

Hair cortisol levels decrease as children age, stabilizing around age 4.

The P133R mutation in AKR1D1 enzyme causes harmful bile acid buildup, explaining related health issues.

The Chinese version of the PCOS quality of life questionnaire is reliable and valid for Chinese-speaking women with PCOS.

Dihydrotestosterone changes some hormone-related gene expressions in rat pituitary glands but doesn't affect the estrous cycle.

Hair cortisol levels in brown bears can be affected by both long-term and short-term stress.

Early diagnosis of Trichorhinophalangeal syndrome type 1 is crucial for treatment and was achieved through clinical examination and family history.

A new test more accurately detects citrulline in hair follicles and pilomatrixomas.

Early diagnosis and nutritional support are crucial for managing Cronkhite-Canada Syndrome.

Metastatic cervical cancer can cause rare, severe Cushing's syndrome with high risk of death.

Corticosteroids improved symptoms in a man with Cronkhite-Canada Syndrome.

Treating non-classic congenital adrenal hyperplasia is complex because the benefits of hormone treatment must be weighed against potential health risks.

Imaging helps detect adrenal gland issues and monitor treatment in congenital adrenal hyperplasia, and can identify tumors affecting fertility.

Distal hair cortisol is not a reliable measure of early pregnancy cortisol levels.