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Hormone therapy for trans individuals is effective and generally safe in the short term.

Hormone therapy can improve mental health and quality of life for people with gender dysphoria, but long-term effects need more research.

Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.

Australian doctors experienced in adult transgender healthcare mostly prescribe intramuscular testosterone and oral estradiol, recommend mental health assessments before hormone therapy, and support improved training and guidelines.

Cross-sex hormone treatment in transsexual individuals helps understand how sex hormones affect diseases like heart disease and diabetes.

Hormone treatment for transgender patients may not need to be stopped before surgery, but more research is needed, especially on estrogen.

In Japan, sex reassignment surgery for gender identity disorder faces challenges and needs better medical support and education.

The document concludes that non-operative treatment for gender dysphoria is safe and effective, and hormone therapy does not increase cancer risk.

Care for gender-dysphoric Veterans can be improved with a consistent, team-based approach.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Most youth with gender dysphoria received hormones, had minor complications, and showed a decrease in suicide attempts after treatment.

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

Combination therapy with oral contraceptives and spironolactone improves hair growth, menstrual issues, and acne in women with PCOS.

The document concludes that gender-affirming treatments are essential for transgender individuals and outlines safe hormone therapy practices.

Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

SHBG may be a useful early indicator and treatment target for PCOS.

Testosterone is key for male sexual function, and treating hormone imbalances can improve sexual issues.

Low testosterone and SHBG levels are linked to higher COVID-19 death rates.

Sex hormones affect reproduction, sexual development, and oral health, and it's important for dental practitioners to understand their effects and interactions.

Most patients improved with oral contraceptives, but some needed additional treatment.

Transgender and nonbinary individuals experience hair loss, with transmen on testosterone seeing more severe hair loss, while feminizing hormones may stabilize hair loss in transwomen.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Hormonal contraceptives and related compounds can increase health risks like thrombosis and affect sexual function.

Insulin resistance is strongly linked to higher androgen levels in women with PCOS.

Hormone therapy in transgender individuals can increase acne and affect hair growth and loss.

Hormone therapy may increase migraines in transgender women and decrease them in transgender men; more research is needed on migraine management in transgender individuals.

Following national healthy eating guidelines can help reduce risks from gender-affirming hormone therapy.

Testosterone replacement may help postmenopausal women with sexual function and bone density, but suitable treatments are limited.