September 2020 in “PubMed” The specialized protective cap improved recovery and satisfaction after hair transplant.
December 2025 in “npj Systems Biology and Applications” Cold temperatures can stop human cell circadian rhythms, but warming restores them.
July 2024 in “Journal of Investigative Dermatology” Scalp cooling may be less effective for women of color on certain chemotherapy treatments.
September 2025 in “Acta Dermato Venereologica” Intralesional corticosteroids may be more effective than cryotherapy for hair regrowth in alopecia areata.
25 citations
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June 2020 in “Dermatology practical & conceptual” Scalp cooling can help prevent hair loss from chemotherapy, but treatment should be tailored to the individual and more research is needed.
64 citations
,
July 2011 in “Dermatologic Therapy” Scalp cooling can prevent chemotherapy-induced hair loss, and certain treatments can speed up hair regrowth, but more research is needed for better treatments.
3 citations
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March 1956 in “PubMed” Surgical skin planing is safe and effective for treating acne scars using a freezing agent that avoids safety risks.
March 2024 in “Research Square (Research Square)” Scalp cooling therapy helps preserve hair during chemotherapy for most patients.
January 2023 in “International Egyptian Journal of Nursing Sciences and Research” Scalp cryotherapy significantly reduces hair loss during and shortly after chemotherapy.
March 2025 in “Tissue and Cell” Frozen-thawed fibroblast sheets enhance wound healing and hair growth in mice.
Hypoxic preconditioning helps human hair follicle stem cells survive oxidative stress.
September 2016 in “한국임상약학회지” Ibuprofen, menthol, and cetirizine may help prevent or slow hair loss.
July 2019 in “Dermatologic Surgery”
November 2025 in “The Journal of Medical Sciences” Intralesional triamcinolone is more effective than cryotherapy for treating alopecia areata in middle-aged adults.
19 citations
,
January 2023 in “ACS Omega” SEF cryogels effectively kill bacteria, stop bleeding, and speed up wound healing.
January 2019 in “Dermatologic Surgery”
10 citations
,
January 2015 in “Journal of Cutaneous Medicine and Surgery” Cold caps and certain drugs may help prevent or reduce hair loss from chemotherapy, but more research is needed.
5 citations
,
June 2024 in “Regenerative Therapy” Storing PRP at -80 °C keeps growth factors stable for at least 6 months.
January 2024 in “International Journal of Health Science” Scalp cooling and low-power light therapy show promise in reducing chemotherapy-induced hair loss but need more research.
10 citations
,
January 2019 in “Biomarker Insights” Scalp cooling to prevent hair loss from chemotherapy works for some but not all, and studying hair damage markers could improve prevention and treatment.
January 2022 in “Aesthetic Plastic Surgery” 1 citations
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January 2021 in “Springer Proceedings in Materials” Researchers developed a new method to clearly see and label hair proteins with minimal errors using advanced freezing and microscopy techniques.
March 2025 in “International Journal of Trichology” Storing hair follicles in 10% DMEM at 37°C improves hair transplant success.
February 2026 in “Journal of Cosmetic Dermatology” Combining triamcinolone acetonide with cryotherapy may reduce scalp hair loss more than using triamcinolone alone.
Some cancer treatments cause different types of hair loss, but scalp cooling can help prevent it.
7 citations
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October 2019 in “Frontiers in bioengineering and biotechnology” Fusion proteins can protect hair from heat damage.
14 citations
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January 2005 in “Cell Stress and Chaperones” November 2025 in “npj Breast Cancer” Tamoxifen increases the risk of lasting hair loss after chemotherapy despite scalp cooling.
11 citations
,
January 2022 in “Methods in cell biology”
6 citations
,
June 2022 in “Frontiers in Bioengineering and Biotechnology” The gel with icariin speeds up wound healing, reduces scarring, and helps hair growth by controlling BMP4 signaling. It also reduces inflammation and improves wound quality in mice, adapts to different wound shapes, and gradually releases icariin to aid healing. It also prevents too much collagen and myofibroblast formation during skin healing.