research Boosting and Rescuing Epidermal Superior Population from Fresh Keratinocyte Cultures
The method increases stem-like cells for better skin regeneration.
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research M-CSF-Stimulated CD11b+ Myeloid Cells Induce Alopecia Areata in C3H/HeJ Mice
M-CSF-stimulated myeloid cells can cause alopecia areata in mice.
research Human hair-follicle associated pluripotent (HAP) stem cells differentiate to cardiac muscle cells
Human hair follicles can produce stem cells that turn into heart muscle cells.
research Editors' Picks
Activin increases skin tumor formation, skin Tregs help hair growth, lymph-node removal doesn't improve melanoma survival, cells can revert to stem cells in wound healing, and skin bacteria produce peptides that may treat infections.
research Safe Selection of Genetically Manipulated Human Primary Keratinocytes with Very High Growth Potential Using CD24
Researchers found a safe and effective way to pick genetically modified skin cells with high growth potential using CD24.
research Generation of the Krt24-CreERT2 Mouse Line Targeting Outer Bulge Hair Follicle Cells
The study created a mouse model to better understand hair follicle stem cells' role in hair growth and repair.
research MSCs: Scientific Support for Multiple Therapies
Mesenchymal Stem Cells (MSCs) are promising for multiple therapies, but more research is needed to fully understand and optimize their use.
research Participation of CD34-enriched mouse adipose cells in hair morphogenesis
CD34+ cells from fat tissue help form hair follicles and blood vessels in skin.
research Markers to Evaluate the Quality and Self-Renewing Potential of Engineered Human Skin Substitutes In Vitro and after Transplantation
Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.
research Developing Human Skin Contains Lymphocytes Demonstrating a Memory Signature
Developing human skin has immune cells with memory-like features.
research Hair Follicle Stem Cells
Hair follicle stem cells can generate all hair cell types, skin, and sebaceous glands.
research Spatial and Single-Cell Transcriptional Profiling Identifies Functionally Distinct Human Dermal Fibroblast Subpopulations
Researchers found four distinct fibroblast types in human skin, which could help in treating wounds and fibrotic diseases.
research O02 Ubiquitomics of CYLD-deficient skin tumours reveals dysregulation of hair follicle keratinocyte processes
CYLD deficiency in skin tumors disrupts hair follicle cell processes and protein secretion.
research 25 Years of Epidermal Stem Cell Research
Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.
research Activation of developmental signaling pathways in hematopoietic stem cell regeneration
Wnt and Notch pathways are crucial for repairing blood stem cells after damage.
research Molecular and cellular mechanisms of differentiation and plasticity processes to form adipocytes
Lower TGFß1 levels help stem cells become beige fat cells.
research Keratin expression by corneal and limbal stem cells during development
Different types of cells in the eye express specific keratins at various stages of development.
research Human dermal Vδ1 + T-cells recognize “stressed” HFs and may induce alopecia areata
Certain immune cells may cause hair loss by reacting to stressed hair follicles.
research In vitro Keratin Expression of Hair Cells
Hair cells grown in a lab showed specific hair proteins.
research Tissue-engineered dermal substitutes constructed by human embryonic stem cell-derived fibroblasts facilitate the repair of skin wounds
Stem cell-derived fibroblasts can effectively repair skin wounds.
research Basal cells in the epidermis and epidermal differentiation
The exact identity of skin stem cells and how skin cells differentiate is not fully known.
research Multipotent nestin-expressing stem cells capable of forming neurons are located in the upper, middle and lower part of the vibrissa hair follicle
Stem cells in hair follicles can become neurons and other cells, especially in the upper part, useful for nerve repair.
research Canine hair‐follicle keratinocytes enriched with bulge cells have the highly proliferative characteristic of stem cells
Canine hair follicles contain stem-like cells with high growth potential.
research Hair Follicle Dermal Stem Cells Regenerate the Dermal Sheath, Repopulate the Dermal Papilla, and Modulate Hair Type
Hair follicle dermal stem cells are key for regenerating parts of the hair follicle and determining hair type.
research KOMÓRKI VSELs KLUCZEM DO DŁUGOWIECZNOŚCI
VSELs may hold the key to longer life through regenerative therapies.
research Epidermal Cells Expressing Putative Cell Markers in Nonglabrous Skin Existing in Direct Proximity with the Distal End of the Arrector Pili Muscle
Certain skin cells near the base of hair muscles may help renew and stabilize skin, possibly affecting skin disorder understanding.
research CUTANEOUS T-CELL LYMPHOMA
The document concludes that DAB389-IL2 is promising for treating refractory cutaneous T-cell lymphoma, but more research is needed on its effectiveness and side effect management.
research Tissue engineering strategies combining molecular targets against inflammation and fibrosis, and umbilical cord blood stem cells to improve hampered muscle and skin regeneration following cleft repair
Combining stem cells and targeted treatments can improve muscle and skin healing after cleft repair.
research Murine skin-derived multipotent papillary dermal fibroblast progenitors show germline potential in vitro
Mouse skin cells can become sperm-like cells in the lab.
research Impaired turnover of autophagolysosomes in cathepsin L deficiency
Cathepsin L deficiency causes large, abnormal cell structures and health issues in mice.