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GlossaryCucurbita pepo

species of plant including pumpkins, zucchinis, and certain squashes

Cucurbita pepo is a species of plant in the gourd family, Cucurbitaceae, which includes varieties such as pumpkins, zucchinis, and certain types of squash. It is widely cultivated for its edible fruit, seeds, and sometimes even its flowers. The plant is also studied for its potential health benefits, including its rich nutrient content and possible antioxidant properties.

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Oral Supplementation with L-Cystine, Serenoa Repens, Cucurbita Pepo, and Pygeum Africanum in Chronic Telogen Effluvium and Androgenetic Alopecia: A Double-Blind, Placebo-Controlled, Randomized Clinical Study

research Oral Supplementation with l-Cystine, Serenoa repens, Cucurbita pepo, and Pygeum africanum in Chronic Telogen Effluvium and Androgenetic Alopecia: A Double-Blind, Placebo-Controlled, Randomized Clinical Study

July 2024 in “Skin Appendage Disorders”

The supplement significantly improves hair density and appearance in people with hair loss.

research Isolation, Structural Elucidation and Therapeutic Potentials of Root of Cucurbita pepo

January 2021

Pumpkin roots contain compounds like Alpha-spinasterol, squalene, and palmitic acid, which may have health benefits like reducing depression, treating certain cancers, and having antibacterial properties.

Retracted Article: Pumpkin Seeds (Cucurbita Pepo Subsp. Ovifera) Decoction Promotes Trichinella Spiralis Expulsion During Intestinal Phase Via 'Weep and Sweep' Mechanism

research RETRACTED ARTICLE: Pumpkin seeds (Cucurbita pepo subsp. ovifera) decoction promotes Trichinella spiralis expulsion during intestinal phase via “Weep and Sweep” mechanism

4 citations , January 2024 in “Scientific Reports”

Pumpkin seeds may help expel parasites, but findings are retracted.

The Beneficial Effects of Pumpkin (Cucurbita Pepo L.) Seed Oil for Men's Health

research The beneficial effects of Pumpkin (Cucurbita pepoL.) seed oil for health condition of men

15 citations , June 2018 in “Food Reviews International”

Pumpkin seed oil may improve prostate health, bladder control, and hair growth in men.

research Anti-Aging, Anti-Inflammatory, and Cytoprotective Properties of Lactobacillus- and Kombucha-Fermented C. pepo L. Peel and Pulp Extracts with Prototype Skin Toner Development

4 citations , October 2025 in “Molecules”

Fermented pumpkin extracts can be effective for anti-aging and skin protection.

Scientific Opinion on the Substantiation of a Health Claim Related to a Combination of Thiamin, Riboflavin, Niacin, Pantothenic Acid, Pyridoxine, D-Biotin, and Pumpkin Seed Oil and Maintenance of Normal Hair Pursuant to Article 13(5) of Regulation (EC) No 1924/2006

research Scientific Opinion on the substantiation of a health claim related to a combination of thiamin, riboflavin, niacin, pantothenic acid, pyridoxine, D‐biotin and pumpkin seed oil and maintenance of normal hair pursuant to Article 13(5) of Regulation (EC) No 1924/2006

1 citations , July 2012 in “EFSA Journal”

The combination of certain vitamins and pumpkin seed oil has not been proven to maintain normal hair.

Phytotherapeutics for the Management of Androgenetic Alopecia: A Narrative Review

research FITOTERÁPICOS PARA O MANEJO DA ALOPECIA ANDROGENÉTICA: UMAREVISÃO NARRATIVA

January 2025

Phytotherapy offers a safer alternative for managing hair loss with fewer side effects.

Phytotherapeutic Alternatives to the Use of Finasteride and Dutasteride as 5-Alpha Reductase Inhibitors in the Treatment of Androgenetic Alopecia: A Review

research Phytotherapeutic Alternatives to the Use of Finasteride and Dutasteride as 5-Alpha Reductase Inhibitors in the Treatment of Androgenetic Alopecia: A Review

January 2024 in “Brazilian Journal of Hair Health”

Some plant-based products might treat hair loss with fewer side effects than current medications.

research Amazing Benefits Of Pumpkin Seed Oil

May 2022 in “Zenodo (CERN European Organization for Nuclear Research)”

Pumpkin seed oil may improve hair growth, heart health, and reduce inflammation.

research Natural Compounds Used for Treating Hair Loss

February 2023 in “Current Pharmaceutical Design”

Natural remedies like certain plants can help reduce hair loss and promote hair growth.

Impact of a Novel Dietary Supplement on Efficacy of Pharmacological Treatments for Androgenic Alopecia: A Real-Life, Multicenter, Randomized, Assessor-Blinded Trial on 225 Subjects

research Impact of a Novel Dietary Supplement on Efficacy of Pharmacological Treatments for Androgenic Alopecia: A Real‐Life, Multicenter, Randomized, Assessor‐Blinded Trial on 225 Subjects

August 2025 in “Journal of Cosmetic Dermatology”

The dietary supplement AGA-P improves the effectiveness of hair loss treatments.

research Edible seeds from Cucurbitaceae family as potential functional foods: Immense promises, few concerns

54 citations , May 2017 in “Biomedicine & Pharmacotherapy”

Edible seeds from the Cucurbitaceae family like pumpkin and watermelon seeds are nutritious and may have health benefits, but eating too much can cause side effects.

research An overview of herbal alternatives in androgenetic alopecia

26 citations , April 2019 in “Journal of Cosmetic Dermatology”

Herbal alternatives like saw palmetto and green tea may offer safe, effective treatment for hormonal hair loss.

research Pumpkin seed oil vs. minoxidil 5% topical foam for the treatment of female pattern hair loss: A randomized comparative trial

4 citations , February 2021 in “Journal of Cosmetic Dermatology”

Pumpkin seed oil slightly outperforms minoxidil foam in treating hair loss with fewer side effects.

research Potential Pharmacological Activities of Pumpkin Seeds as a Functional Food: A Comprehensive Review

June 2023 in “Journal of Ayurvedic and herbal medicine”

Pumpkin seeds may improve health due to their rich nutrients and potential to treat various conditions.

Niosomal Delivery of Pumpkin Seed Oil: Development, Characterization, and Physical Stability

research Niosomal delivery of pumpkin seed oil: development, characterisation, and physical stability

13 citations , February 2019 in “Journal of Microencapsulation”

The pumpkin seed oil niosomes are promising for skin and hair treatments because they are stable and effectively deliver the oil.

research Plants used in cosmetics

434 citations , October 2003 in “PTR. Phytotherapy research/Phytotherapy research”

Natural products in cosmetics are beneficial for skin and hair care with low toxicity.

research Polysaccharides from Traditional Chinese Medicines: Extraction, Purification, Modification, and Biological Activity

125 citations , December 2016 in “Molecules”

Substances from Chinese medicines show promise for immune support and disease prevention, but the way they are processed affects their effectiveness.

research What do we know about phytotherapy of benign prostatic hyperplasia?

67 citations , February 2015 in “Life Sciences”

Some plant-based treatments can help with benign prostatic hyperplasia symptoms, but more research is needed to confirm their safety and effectiveness.

research Complementary and Alternative Treatments for Alopecia: A Comprehensive Review

40 citations , August 2018 in “Skin appendage disorders”

Some alternative treatments for hair loss might work, but more research is needed.

research Plants Producing Ribosome-Inactivating Proteins in Traditional Medicine

40 citations , November 2016 in “Molecules”

Some plants used in traditional medicine may help treat cancer because they contain proteins that can inactivate ribosomes.

Efficacy and Side Effects of Drugs Commonly Used for the Treatment of Lower Urinary Tract Symptoms Associated With Benign Prostatic Hyperplasia

research Efficacy and Side Effects of Drugs Commonly Used for the Treatment of Lower Urinary Tract Symptoms Associated With Benign Prostatic Hyperplasia

35 citations , May 2020 in “Frontiers in Pharmacology”

Different drugs for prostate-related urinary symptoms work but have various side effects, and treatment should be tailored to the individual.

research Middle East Medicinal Plants in the Treatment of Diabetes: A Review

32 citations , January 2021 in “Molecules”

Some Middle Eastern plants may help treat diabetes and could be alternatives to current drugs, but more research is needed.

Multiple Readout Assay for Hormonal (Androgenic and Antiandrogenic) and Cytotoxic Activity of Plant and Fungal Extracts Based on Differential Prostate Cancer Cell Line Behavior

research Multiple readout assay for hormonal (androgenic and antiandrogenic) and cytotoxic activity of plant and fungal extracts based on differential prostate cancer cell line behavior

19 citations , August 2014 in “Journal of Ethnopharmacology”

The study created a test that found hormonal and toxic effects in plant and fungal extracts using prostate cancer cells.

The New Paradigm for Androgenetic Alopecia and Plant-Based Folk Remedies: 5α-Reductase Inhibition, Reversal of Secondary Microinflammation, and Improving Insulin Resistance

research The new paradigm for androgenetic alopecia and plant-based folk remedies: 5α-reductase inhibition, reversal of secondary microinflammation and improving insulin resistance

16 citations , September 2018 in “Journal of Ethnopharmacology”

Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.

research Effects on Steroid 5-Alpha Reductase Gene Expression of Thai Rice Bran Extracts and Molecular Dynamics Study on SRD5A2

14 citations , April 2021 in “Biology”

Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.

Development and Characterization of Phyto-Vesicles of Beta-Sitosterol for the Treatment of Androgenetic Alopecia

research Development and characterization of phyto-vesicles of β-sitosterol for the treatment of androgenetic alopecia

14 citations , December 2011 in “Archives of Dermatological Research”

Phyto-vesicles of β-sitosterol may effectively treat hair loss.

research Changes in European Legislation Make it Timely to Introduce a Transparent Market Surveillance System for Cosmetics

12 citations , January 2007 in “Acta dermato-venereologica”

Europe needs a clear system to watch over cosmetics for safety and to make sure product claims are true.

research Recent Trends and Future Prospects of Phytosomes: A Concise Review

11 citations , January 2024 in “Indian Journal of Pharmaceutical Sciences”

Phytosomes improve the body's absorption of plant extracts for better health benefits.

Early Plant Growth and Biochemical Responses Induced by Azospirillum Brasilense Sp245 Lipopolysaccharides in Wheat (Triticum Aestivum L.) Seedlings Are Attenuated by Procyanidin B2

research Early plant growth and biochemical responses induced by Azospirillum brasilense Sp245 lipopolysaccharides in wheat (Triticum aestivum L.) seedlings are attenuated by procyanidin B2

11 citations , March 2018 in “Protoplasma”

Lipopolysaccharides boost wheat seedling growth, but procyanidin B2 weakens this effect.