7 citations
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January 1998 in “PubMed” Hair loss can cause scalp discomfort.
Perming, combing, and stretching damage hair by reducing keratin levels.
158 citations
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December 2002 in “Development” Msx2-deficient mice experience irregular hair growth and loss due to disrupted hair cycle phases.
43 citations
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September 2006 in “Annals of Plastic Surgery” A hair wrapped tightly around an infant's toe caused severe damage, requiring early removal and possibly surgery to prevent worse outcomes like amputation.
February 1988 in “Journal of the American Academy of Dermatology” 2 citations
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May 2022 in “Stem cell research & therapy” Disrupted stem cell signals in hairpoor mice cause hair loss.
12 citations
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March 2004 in “Journal of Investigative Dermatology”
8 citations
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November 2015 in “The American journal of dermatopathology/American journal of dermatopathology” Punctate follicular porokeratosis is a skin condition with specific features seen in hair follicles.
29 citations
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August 2005 in “Biopolymers” L-cysteine slows down the breaking of bonds in hair due to electrostatic interactions.
21 citations
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January 2005 in “Skinmed” Hair and nails are similar keratin structures with different shapes and growth, affected by the same diseases and environmental factors.
39 citations
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November 2009 in “Clinical and Experimental Dermatology” Immune privilege collapse in hair follicles may cause permanent hair loss in certain conditions.
July 2025 in “Case Reports in Dermatology” Early detection and treatment are crucial to prevent irreversible hair loss in Lichen Planopilaris.
18 citations
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March 1992 in “Archives of Dermatology” The man's scarring alopecia and skin issues did not improve with treatments.
26 citations
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January 1983 in “PubMed” Trichothiodystrophy involves brittle hair due to low sulfur amino acids, not a transport defect.
42 citations
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September 2003 in “Journal of Investigative Dermatology” A missing mK6irs1 gene causes hair loss in mice.
A six-year-old girl with extra hair on her elbows was treated with hair removal methods.
84 citations
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October 2005 in “Annals of Clinical Psychiatry” Hairpulling, skin picking, and nail biting cause significant harm and need more research for better treatments.
2 citations
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August 2004 in “Veterinary Dermatology” A dog with a hereditary skin condition causing blisters and hair loss survived for a year.
5 citations
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July 2009 in “Clinical and experimental dermatology” February 2013 in “Journal of the American Academy of Dermatology” Uncombable hair syndrome causes dry, frizzy hair that can't be combed flat, seen in a young child.
March 2026 in “South Asian Research Journal of Medical Sciences” Removing keratin plugs and ingrown hairs improved scalp inflammation.
4 citations
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December 2022 in “Advanced science” SCD1 is important for hair growth by keeping the connection in skin cells where hair stem cells live stable.
October 2020 in “Pediatrics in Review” The newborn was diagnosed with a rare skin disorder causing blisters, which requires careful wound care and family support.
40 citations
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July 2019 in “Journal of Investigative Dermatology” Lack of a key enzyme causes severe skin issues and death in mice.
101 citations
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July 1985 in “Journal of the American Academy of Dermatology” Biotin improved hair growth and combability in one child with uncombable hair syndrome.
8 citations
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April 2017 in “Journal of Dermatological Science” Hair loss is caused by the breakdown of a protein called COL17A1 in hair follicle stem cells.
13 citations
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October 2004 in “Anais Brasileiros De Dermatologia” The document concludes that compulsive hair disorders, like trichotillomania, are complex and require careful diagnosis and treatment from both psychiatric and dermatological perspectives.
September 2023 in “Cutis” A baby girl has a hair disorder called monilethrix, causing fragile hair that may improve over time.
2 citations
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July 2021 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas” Hair shaft disorders are diagnosed through examination and history, with general care and some treatments offering improvement.