research The keratins and their disorders
Mutations in keratin genes cause cell fragility and various skin disorders.
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900-930 / 1000+ resultsresearch Canine hair‐follicle keratinocytes enriched with bulge cells have the highly proliferative characteristic of stem cells
Canine hair follicles contain stem-like cells with high growth potential.
research In This Issue
Hedgehog signaling is crucial for hair development, cadherins affect cell adhesion, neutrophils play a role in skin lesions, and BP230 autoantibodies impact skin stability.
research Network analysis reveals potential mechanisms that determine the cellular identity of keratinocytes and corneal epithelial cells through the Hox/Gtl2-Dio3 miRNA axis
Hox proteins help maintain keratinocyte identity by regulating miRNA expression.
research Two Dogs with Juvenile-Onset Skin Diseases with Involvement of Extremities
The analyses helped identify different skin diseases in the two dogs.
research Investigation of transfollicular caffeine penetration using microdialysis on ex vivo porcine ear skin
Caffeine penetrates skin quickly through open hair follicles, but less through closed ones, with levels becoming equal after 22 hours.
research Epidermal Barrier
Healthy skin prevents water loss and protects against threats.
research 855 Targeted deletion of crif1 in mouse skin epidermis impairs skin homeostasis
Removing the Crif1 gene in mouse skin disrupts skin balance and hair growth.
research Research Articles : New Evidence for the Involvement of the EGF Receptor Pathway in Hair Follicle Morphogenesis in uncv Mice
research The Morphological Basis of vicuña wool: Skin and gland structure in Vicugna vicugna (Molina 1782)
Vicuña wool's quality is due to a high density of fine secondary hair follicles, and their skin glands may be used for communication.
research 371 Hair follicles are critical modulators of skin barrier function
Hair follicles are crucial for maintaining skin barrier function.
research Spatiotemporal dynamics of sensory neuron and Merkel-cell remodeling are decoupled during epidermal homeostasis
Merkel cells stabilize nerve endings in the skin, and they change independently of each other.
research Hair Follicle Proteoglycans.
research Involucrin: A Constituent of Cross-Linked Envelopes and Marker of Squamous Maturation
Involucrin is crucial for skin cell maturation and protection.
research Commentary for Treatment of Thin Linear Scars on the Scalp
Double trichophytic closure effectively repairs thin scalp scars, reducing financial burden.
research Differential structural properties and expression patterns suggest functional significance for multiple mouse desmoglein 1 isoforms
Multiple mouse desmoglein 1 isoforms have distinct roles in skin and hair development.
research Organization and Expression of Hair Follicle Genes.
Hair growth is controlled by specific gene clusters and proteins, and cysteine affects hair gene expression in sheep.
research Transdifferentiation of corneal epithelium into epidermis occurs by means of a multistep process triggered by dermal developmental signals
Corneal cells can transform into skin and hair cells through specific signals.
research Molecular histology in skin appendage morphogenesis
New molecules involved in skin and hair growth were identified, improving understanding and future treatments.
research Onychogryphosis by an elastic wire
research Chapter 4 Cytomechanics of Hair
Hair's strength and flexibility come from its protein structure and molecular interactions.
research Structural and biochemical changes underlying a keratoderma-like phenotype in mice lacking suprabasal AP1 transcription factor function
Inhibiting AP1 in mice skin causes structural changes and weakens the skin barrier.
research Padrão dermatoscópico das alopecias cicatriciais causadas por lúpus eritematoso discoide e líquen plano pilar
Dermoscopy helps diagnose and monitor treatment for hair loss from scarring conditions like discoid lupus and lichen planopilaris.
research Characterization of new stem/progenitor cells in skin appendages
New stem cells in nails and sweat glands can regenerate skin and hair.
research Clinical Snippets
Glycerol may improve wound healing and prevent keloids, a device can measure itch intensity, male pattern baldness is highly heritable, and fumaric acid esters may work for psoriasis by causing cell death in T cells.
research Beyond the Epidermal-Melanin-Unit: The Human Scalp Anagen Hair Bulb Is Home to Multiple Melanocyte Subpopulations of Variable Melanogenic Capacity
The human scalp has different types of pigment cells in hair follicles with varying abilities to produce pigment.
research FEA-guided co-design of bubble microneedles: controlled tip separation for rapid transdermal and sublingual delivery
Bubble microneedles effectively deliver drugs through skin and mouth, improving hair growth and lowering glucose.
research 085 Dermal papilla cells control hair follicle matrix keratinocytes proliferation through versican
Versican in dermal papilla cells is crucial for healthy hair growth.
research Pigmented Hair-Thickening Fibers: A Camouflage Technique for Alopecia in Patients with Epidermolysis Bullosa
Colored hair-thickening fibers can help hide hair loss in some people with Epidermolysis Bullosa but may cause scalp irritation.
research The Utility of De-epithelialization in Subcutaneous Skin Flap Transposition.
De-epithelialization reduces complications in subcutaneous skin flap procedures.