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Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

PROTACs show promise in cancer treatment by effectively degrading specific harmful proteins.

Two existing drugs may help treat COVID-19 by inhibiting a key viral protein.

Cepharanthine effectively reduces Herpes Simplex Virus Type 1 by blocking certain cell pathways and promoting cell death.

TICE salvage chemotherapy is effective for treating germ-cell tumors with poor prognosis.

Compound 4 is a promising treatment for hair loss with low toxicity.

LncRNA MTC boosts growth of goat skin cells, improving cashmere quality.

Cepharanthine analogues, especially tetrandrine, show potential for treating COVID-19.

Xeno-free three-dimensional stem cell masses are safe and effective for improving blood flow and tissue repair in limb ischemia.

CXCR2 in skin cells promotes tumor growth.

Combining immune checkpoint inhibitors with other cancer therapies increases skin side effects in Asian patients.

The new chemotherapy combination of WP 631 and Epothilone B shows enhanced effectiveness against ovarian cancer but requires more research on its safety.

JAK inhibitors show promise for treating skin and hair disorders but need more research on long-term safety and effectiveness.

Pexidartinib often causes liver issues and fatigue, especially in women.

Blocking SCD1 in the skin with XEN103 shrinks sebaceous glands in mice.

Some synthetic carbohydrate receptors, especially compounds 3 and 15, show strong potential for treating Zika virus.

The document concludes that biotin, folate, and RGD peptides are promising for targeting cancer cells with prodrugs, but the conjugates are not yet tested for use.

RNA aptamers can specifically block FGF5-related cell growth, potentially treating related diseases or hair disorders.

Y27632 increases cell growth through EGFR signaling, not ROCK1/2.

ZD1839, a cancer drug, can cause mild skin rashes that are treatable without stopping the medication.

Two new mutations in the CDH3 gene cause hair loss and vision problems in a young girl.

Some cancer and immune system drugs can cause serious side effects, including heart, lung, nerve, and organ damage, which need careful monitoring and management.

Plerixafor may help treat pigmentation disorders by promoting skin repigmentation.

ISX-9 helps stem cells heal lung injury better by boosting growth factor secretion.

PROTACs offer a new, precise way to treat cancer by breaking down harmful proteins.

Rapamycin may help treat Leigh syndrome by targeting protein kinase C.

Upadacitinib effectively treats pyoderma gangrenosum.

Deucravacitinib effectively treats psoriasis and may help with other skin conditions.

ITK inhibitors may effectively treat alopecia areata.

Peptide nanoparticles can effectively deliver CRISPR-Cas9 to target KRAS mutations in cancer.