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Different types of PCOS have different levels of metabolic problems, with the most severe type showing the highest disturbances.

The reconstructed skin model from hair follicles functions like human skin in processing chemicals and can be used to test ingredient safety.

Targeting 5α-reductase type 1 may help manage Tourette-like symptoms.

A new type of pachyonychia congenita linked to a specific keratin gene mutation was found in two Pakistani families.

Truncating mutations in the C2orf37 gene cause Woodhouse–Sakati syndrome.

Certain gene variations are linked to a higher risk of severe acne, suggesting a genetic influence on the condition.

Some common medications can lower PSA levels in 45-year-old German men.

A new gene, JMJD1C, may affect testosterone levels in men.

Certain gene variations in the Vitamin D receptor may increase the risk of chronic hair loss.

Not having enough cystatin M/E protein causes less hair growth and dry skin.

A new mutation linked to partial Androgen Insensitivity Syndrome and prostate cancer was found in a patient unhappy with their female gender assignment.

Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.

PCOS diagnosis and treatment should consider race and ethnicity for accuracy.

Finasteride increases CD8+ T cells in BPH tissues.

A Japanese patient with IFAP syndrome had a severe MBTPS2 gene mutation but showed milder symptoms than previously observed cases.

New steroidal compounds moderately block an enzyme related to testosterone conversion, less effectively than finasteride.

A new mutation in the HJV gene was found in a young woman with juvenile hemochromatosis, causing unusual symptoms like secondary hypothyroidism.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Urologists prescribe newer medications more often than primary care physicians, who could benefit from more education on treatment options.

Mutations in the PADI3 gene may cause central centrifugal cicatricial alopecia in women of African ancestry.

Certain hormone levels can help diagnose P450 oxidoreductase deficiency.

Three genes linked to the development of trichilemmal cysts were found.

Micelles can change cetirizine's ionization, affecting its effectiveness in treatments.

A Chinese family had a child with a specific gene mutation causing vitamin D-resistant rickets, but the child improved with calcium and low-dose calcitriol.

Anastrozole and cyproterone acetate treatment can help increase adult height in boys with testotoxicosis.

The report expanded knowledge of MBTPS1-related disorders by identifying new symptoms.

Ketoconazole increases finasteride's effectiveness and lifespan in the body.

A new gene mutation caused a man's rare skin condition, Schöpf-Schulz-Passarge syndrome.