2 citations
,
February 2022 in “Frontiers in Endocrinology” Antiandrogenic pretreatment for women with PCOS does not improve fertility outcomes and delays pregnancy.
117 citations
,
May 2017 in “Human Reproduction Update” The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.
75 citations
,
March 1999 in “Fertility and sterility” Finasteride, CPA, and flutamide are all equally effective in reducing excessive hair growth in women.
55 citations
,
March 2000 in “American journal of clinical dermatology” Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.
31 citations
,
September 2020 in “Clinical endocrinology” Some antiandrogens may lower testosterone better than others, but it's unclear which is best for feminization in transgender women; more research is needed.
20 citations
,
August 1987 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” Aldactone was more effective in reducing hair growth in women with hirsutism than Diane, despite having less impact on hormone levels.
17 citations
,
January 1984 in “Psychotherapy and psychosomatics” Antiandrogen treatment can reduce sexual enjoyment in women with excess male hormones, especially those in stable relationships.
16 citations
,
July 2002 in “JOGC/Journal of obstetrics and gynaecology Canada” Birth control pills can help reduce mild to moderate acne in women.
7 citations
,
August 2020 in “Health and Quality of Life Outcomes” Birth control pills containing cyproterone acetate improve the quality of life more for women with polycystic ovary syndrome after 6 months of use.
7 citations
,
September 2017 in “Pharmacoepidemiology and Drug Safety” The use of Diane-35 and its generics significantly decreased in the Netherlands.
7 citations
,
September 1988 in “Baillière's clinical obstetrics and gynaecology” Cyproterone acetate is effective for treating hirsutism and acne in women by blocking androgens in the skin and also works as a contraceptive.
7 citations
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May 1983 in “Geburtshilfe und Frauenheilkunde” Intramuscular cyproterone acetate effectively treats hirsutism and improves skin conditions in women with hyperandrogenism.
5 citations
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January 1984 in “Journal of psychosomatic obstetrics and gynecology/Journal of psychosomatic obstetrics and gynaecology” The treatment reduced hair growth and testosterone in women with excess hair and had some effects on stress responses.
4 citations
,
April 2016 in “Journal of Dermatology Research and Therapy” Anti-androgens are safe and effective for treating moderate to severe adult female acne.
3 citations
,
January 2018 in “Reproduction, Fertility and Development” Birth control pills increase certain receptor activities in female gerbil prostate glands and can lead to prostate changes.
3 citations
,
May 2002 in “Therapeutische Umschau” The document concluded that cyproterone acetate and minoxidil are effective for female hair loss, and a supportive doctor-patient relationship is important.
2 citations
,
November 2025 in “Journal of Ovarian Research” Reducing granulosa cell pyroptosis may improve oocyte maturation in PCOS.
2 citations
,
February 2003 in “Obstetrical & Gynecological Survey” Most antiandrogen treatments effectively reduce acne in hyperandrogenic women, but finasteride is the least effective.
1 citations
,
January 2001 in “Endocrine Practice” Topical finasteride may help treat facial hirsutism in women.
1 citations
,
November 1996 in “Journal of Cutaneous Medicine and Surgery” Hormones, especially androgens, play a key role in causing acne, and treatments like hormone control pills and hormone-blocking medications can help.
1 citations
,
January 1979 in “International Journal of Dermatology” Cyproterone acetate effectively treats hirsutism and related conditions.
October 2025 in “Minerva Obstetrics and Gynecology” Choosing the right estroprogestin is crucial for effectively managing PCOS symptoms.
April 2020 in “Research Square (Research Square)” Oral contraceptives with cyproterone acetate improved quality of life for women with PCOS more than those with levonorgestrel.
Antiandrogen treatment helps reduce hair follicles and sebaceous glands in hirsute women.
July 2002 in “JOGC/Journal of obstetrics and gynaecology Canada” Birth control pills help treat acne, especially when caused by excess male hormones, and are safe to use with antibiotics.
4 citations
,
July 2006 in “British journal of dermatology/British journal of dermatology, Supplement” Testosterone increases hair follicle cell growth when beard or axillary skin cells are present together.
November 2025 in “Cochrane Database of Systematic Reviews” Cyproterone acetate works similarly to other treatments for hirsutism, but more research is needed.
35 citations
,
October 2005 in “European journal of pharmaceutics and biopharmaceutics” Polymers increased skin permeation and stability of steroid hormones in liposomal formulations.
7 citations
,
January 1994 in “Annual Reports in Medicinal Chemistry” Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.
9 citations
,
June 1999 in “Acta Obstetricia Et Gynecologica Scandinavica” Oral contraceptives are effective for treating hyperandrogenism, while ovarian electrocautery is better for women with infertility.