Effects of Oral Contraceptives on the Quality of Life of Women with Polycystic Ovary Syndrome: A Crossover Randomized Controlled Trial

    August 2020 in “ Health and Quality of Life Outcomes ”
    Mina Amiri, Fatemeh Nahidi, Razieh Bidhendi Yarandi, Davood Khalili, Maryam Tohidi, Fahimeh Ramezani Tehrani
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    TLDR Birth control pills containing cyproterone acetate improve the quality of life more for women with polycystic ovary syndrome after 6 months of use.
    In 2020, a study was conducted on 88 women with polycystic ovary syndrome (PCOS) to compare the effects of different oral contraceptives (OCs) on their quality of life (QOL). The OCs contained either levonorgestrel (LNG), desogestrel (DSG), cyproterone acetate (CPA), or drospirenone (DRSP). After 3 months, there was no significant difference in QOL between the groups. However, after 6 months, those treated with OCs containing CPA showed a greater improvement in their total QOL scores compared to those treated with LNG. The study concluded that OCs with newer progestins were not superior in improving QOL, but OCs containing CPA were associated with more improvement in total QOL of PCOS patients after 6 months of treatment.
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