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ISCK03 stops melanin production in human melanoma cells and lightens skin color in mice and guinea pigs.

MCHR2 gene duplications may be linked to alopecia areata.

A patient with Ivemark syndrome developed mixed type vitiligo after a hepatitis C infection, showing different treatment responses and immune cell involvement in the skin.

Skin lesions in Carney complex are likely caused by a specific group of skin cells that promote pigment production due to a genetic mutation.

A rare genetic mutation causes Woodhouse-Sakati syndrome symptoms.

Disrupted cholesterol production impairs hair follicle stem cells, leading to hair loss.

Mutations in the PADI3 gene may cause central centrifugal cicatricial alopecia in women of African ancestry.

Type 1/17 inflammation in psoriasis increases skin cell growth due to a molecule that could be a new treatment target.

UV radiation may cause DNA changes in skin, certain UVB therapy helps psoriasis, a new gene mutation is linked to mild piebaldism, different immune cells affect psoriasis, a drug promotes hair growth, and some cancer drugs could treat skin barrier issues.

Cyclosporine A treatment caused rare hair repigmentation in a 65-year-old man.

Prostate cancer was a major health issue in 2009, especially for Black men, and targeting the 5alpha-reductase enzyme could help in its prevention and treatment.

AKR1C3 could be a treatment target for metabolic issues in PCOS.

Finasteride may treat baldness but less effective for those with 5α-reductase deficiency.

A new green method accurately measures finasteride and tadalafil in drugs and plasma.

Nonclassic adrenal hyperplasia is a genetic condition that can cause early puberty and fertility problems, treated with specific steroids.

Activating Nrf2 protects human hair follicles from oxidative stress and helps prevent hair growth inhibition.

Certain gene variations in AKT2 are more common in women with PCOS and are linked to higher levels of specific hormones and symptoms.

Rapamycin treatment helps with mitochondrial disease by reducing PKC levels.

A protein called CBP is found in prostate cancer and can increase the effectiveness of certain prostate cancer treatments.

High levels of TNF-α may contribute to obesity and insulin resistance in PCOS, but not due to the C850T genetic variation.

Vitamin E affects liver metabolism, enhancing stress resistance, reducing blood clotting, and altering hormone processing.

A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.

Hair steroid measurement is an effective method to diagnose and monitor CAH in developing countries.

Scientists discovered a new way UVB light increases skin pigmentation through the ATP-P2X7 pathway.

5α-reductase 2 is crucial for stress response in male rats.