research Alopecia areata update
Despite progress in treatment, the exact cause of Alopecia areata is still unknown.
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research Activin B Promotes BMSC-Mediated Cutaneous Wound Healing by Regulating Cell Migration via the JNK—ERK Signaling Pathway
Activin B improves wound healing and hair growth by helping stem cells move using certain cell signals.
research Roles of tumor suppressors in regulating tumor-associated inflammation
Tumor suppressors help control inflammation in cancer and restoring their function could lead to new treatments.
research Thyrotropin-releasing hormone and oestrogen differentially regulate prolactin and prolactin receptor expression in female human skin and hair follicles in vitro
Oestrogen and thyrotropin-releasing hormone affect prolactin and its receptor in human skin and hair, suggesting new treatment options for related conditions.
research The bright side of fibroblasts: molecular signature and regenerative cues in major organs
Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.
research Cellular senescence in tissue repair: every cloud has a silver lining
Cell aging can be both good and bad for tissue repair.
research MicroRNAs in the skin: role in development, homoeostasis and regeneration
MicroRNAs are important for skin health and could be targets for new skin disorder treatments.
research Enhanced remyelination during late pregnancy: involvement of the GABAergic system
Late pregnancy helps repair brain damage in rats due to the GABAergic system.
research Endocrine evaluation of hirsutism
Women with excessive male-pattern hair growth should get a full hormone check-up to find and treat any underlying issues, considering both medical and emotional aspects.
research Contribution of androgens to chronic allograft nephropathy is mediated by dihydrotestosterone
Male hormones worsen kidney transplant damage, but blocking them helps.
research Friends Turned Foes: Angiogenic Growth Factors beyond Angiogenesis
Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.
research Exfoliative cutaneous lupus erythematosus in German shorthaired pointer dogs: disease development, progression and evaluation of three immunomodulatory drugs (ciclosporin, hydroxychloroquine, and adalimumab) in a controlled environment
Hydroxychloroquine showed some potential, but overall, the three drugs had limited success in treating lupus in dogs.
research Problems and Solutions for Platelet-Rich Plasma in Facial Rejuvenation: A Systematic Review
PRP shows promise for improving facial wrinkles, skin elasticity, and hair growth, but more research is needed to standardize its use and understand its effects.
research Human placental extract exerts hair growth-promoting effects through the GSK-3β signaling pathway in human dermal papilla cells
Human placental extract may help hair growth by affecting certain cell signals and could be more effective with minoxidil.
research Novel Anti-Melanogenesis Properties of Polydeoxyribonucleotide, a Popular Wound Healing Booster
Polydeoxyribonucleotide (PDRN) may help lighten skin and treat hyperpigmentation.
research Transforming Growth Factor-??, Smad, and Collagen Expression Patterns in Fetal and Adult Keratinocytes
Keratinocytes show more TGF-β system activity and collagen production as they age, which might affect wound scarring.
research Alopecia in IL-10-deficient mouse pups is c-kit-dependent and can be triggered by iron deficiency
Hair loss in certain young mice is linked to a specific gene and can be caused by lack of iron.
research Basic mechanisms of SARS-CoV-2 infection. What endocrine systems could be implicated?
SARS-CoV-2, the virus causing COVID-19, can affect all endocrine organs and systems, altering their function and potentially leading to disorders. Factors like diabetes and obesity increase infection risk and severity. Understanding these effects is key for effective treatment.
research Chi-miR-30b-5p inhibits dermal papilla cells proliferation by targeting CaMKIIδ gene in cashmere goat
A specific microRNA, chi-miR-30b-5p, slows down the growth of hair-related cells by affecting the CaMKIIδ gene in cashmere goats.
research Hair Restoration in Androgenetic Alopecia: Looking Beyond Minoxidil, Finasteride and Hair Transplantation
Alternative treatments show promise for hair growth beyond traditional methods.
research COVID-19 infection leading to acute pustular dermatoses
COVID-19 can directly trigger certain skin conditions like pustular dermatoses due to an inflammatory response.
research Cardiodermatology: the heart of the connection between the skin and cardiovascular disease
Skin conditions can signal heart issues, highlighting the need for integrated care.
research New small molecules in dermatology: for the autoimmunity, inflammation and beyond
New small molecule drugs show promise in treating complex skin diseases but need more safety research.
research Humanized CXCL12 antibody delays onset and modulates immune response in alopecia areata mice: insights from single-cell RNA sequencing
A humanized CXCL12 antibody may delay and treat alopecia areata by altering the immune response.
research The ‘bald’ phenotype (androgenetic alopecia) is caused by the high glycaemic, high cholesterol and low mineral ‘western diet’
Western diet may cause male pattern baldness; low glycemic diet with magnesium could help.
research Topical Antiandrogen Therapies for Androgenetic Alopecia and Acne Vulgaris
Topical therapies show promise for hair loss and acne treatment with minimal side effects.
research Endocrine evaluation of hirsutism
Hirsutism, excessive hair growth in women, is often caused by PCOS and can be managed with medication and personalized treatment plans.
research Activin B Promotes Initiation and Development of Hair Follicles in Mice
Activin B helps start and grow hair follicles in mice.
research Platelet-rich plasma as a potential antimicrobial agent against multidrug-resistant bacteria in diabetic foot infections
Platelet-rich plasma can temporarily inhibit some drug-resistant bacteria in diabetic foot infections.
research Restoring neuropetide Y levels in the hypothalamus ameliorates premature aging phenotype in mice
Increasing neuropeptide Y in the brain can slow aging signs in mice.