185 citations
,
February 2018 in “Journal of Investigative Dermatology” Melatonin may benefit skin health and could be a promising treatment in dermatology.
44 citations
,
October 2019 in “International Journal of Molecular Sciences” Melatonin, usually known for sleep regulation, also has antioxidant properties that can protect skin, stimulate hair growth, and improve skin conditions, with topical application being more effective than oral use.
42 citations
,
May 2007 in “Endocrinology and metabolism/American journal of physiology: endocrinology and metabolism” Testosterone can build muscle and bone without enlarging the prostate when a specific enzyme is blocked.
20 citations
,
November 2022 in “Nutrients” Placenta extract may protect and improve liver health by reducing stress, inflammation, and cell death, and promoting regeneration.
20 citations
,
August 1997 in “PubMed” Increased K+ permeability alone may not promote hair growth.
12 citations
,
April 2020 in “British Journal of Dermatology” Caffeine may help reduce stress-induced hair loss.
12 citations
,
January 2011 in “Dermatologic Surgery” Retinoids can prevent skin cancer in high-risk people but have side effects and require more research on dosing and effectiveness.
8 citations
,
February 2009 in “Current Women's Health Reviews” Testosterone treatment can improve sexual function and bone density in women but may have adverse effects and requires more research on safety and guidelines.
7 citations
,
April 2000 in “Archives of Pathology & Laboratory Medicine” 1 citations
,
June 2022 in “Frontiers in Neuroanatomy” Early hormones shape sex-specific differences in rat glands.
1 citations
,
January 2017 in “Evolutionary studies” Different human traits like skin color and hair type vary between populations due to genetic adaptations to the environment.
Low-dose oral minoxidil is generally safe for treating hair loss, with mostly mild side effects.
June 2008 in “Experimental dermatology” Melatonin protects skin and hair from damage and stress by acting as an antioxidant and influencing cell growth.
1 citations
,
August 2022 in “Plant Signaling & Behavior” Growth media with sucrose and gelrite significantly enhance Arabidopsis root hair growth.
7 citations
,
January 2022 in “Scientific Reports” Acanthus ebracteatus Vahl. extract and verbascoside may help prevent hair loss and promote hair growth due to their anti-inflammatory properties and ability to protect against cell death.
6 citations
,
July 2023 in “Plants” Datura metel leaf extracts help heal wounds effectively.
2 citations
,
March 2022 in “Applied sciences” Lespedeza bicolor extract promotes hair growth and increases hair follicle cell growth, potentially making it a better treatment than minoxidil.
December 2025 in “Clinical and Translational Science” EGFR inhibitors in breast cancer treatment can cause serious skin issues affecting patient quality of life.
December 2024 in “International Journal of Molecular Sciences” Platelet-rich fibrin may help reduce nonmelanoma skin cancer cell growth.
July 2021 in “Asia-Pacific journal of convergent research interchange” Cauliflower Mushroom extract may help treat male hair loss by affecting hair growth-related genes.
11 citations
,
September 2022 in “World Journal of Advanced Pharmaceutical and Medical Research” Nicotiana tabacum has potential therapeutic uses but also poses toxic risks.
1 citations
,
July 2023 in “F&S Reviews” Some common medications may harm male fertility by affecting hormones, sperm production, and sexual function.
60 citations
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July 2020 in “ACS Nano” Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.
60 citations
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September 2015 in “Expert Review of Clinical Immunology” Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.
60 citations
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May 2015 in “Archives of dermatological research” PPAR agonists show promise for skin conditions but need more research before being a main treatment.
56 citations
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January 2004 in “Dermatology” Most patients treated with low-dose alpha-interferon for malignant melanoma experienced skin side effects, with hair loss being the most frequent.
44 citations
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April 2023 in “Genes & Diseases” Mesenchymal stem cells release substances that help tissue repair, and their effectiveness can be improved by understanding environmental influences.
26 citations
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July 2012 in “Endocrine Connections” Mitotane changes steroid breakdown, affecting cortisol availability.
20 citations
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February 2018 in “Cell transplantation” Cinnamomum osmophloeum leaf extract may help treat hair loss by promoting hair growth and increasing hair cell proliferation.
19 citations
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October 2008 in “Journal der Deutschen Dermatologischen Gesellschaft” Anti-cancer treatments can cause reversible hair loss, skin sensitivity, pigmentation changes, nail damage, and skin reactions, with a need for more research on managing these side effects.