research Control of testosterone 5alpha-reductase activity in the human hyperplastic prostate
Inhibiting testosterone 5alpha-reductase may help treat benign prostatic hyperplasia.
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research 43046 Outcomes of Down-Titration in Patients with Severe Scalp Alopecia Areata Treated with Baricitinib 4 Mg: Week 104 Data from BRAVE-AA2
Reducing the dose of Baricitinib to 2mg led to a loss of hair regrowth benefits in nearly half of the patients by Week-104.
research Rapid determination of finasteride in human plasma by UPLC–MS/MS and its application to clinical pharmacokinetic study
New method measures finasteride in blood quickly and accurately.
research Why Odds Ratios Can Be Tricky Statistics
Odds Ratios can be misleading; it's better to also present risk and Relative Risks for clarity.
research 7410 Bevacizumab Induced Hypothyroidism
Bevacizumab may worsen hypothyroidism, so thyroid function should be monitored during treatment.
research Experimental Evaluation of 3-meta-Pyridine-1,2,4-Oxadiazole Derivative of Deoxycholic Acid as a Prototype of 5-α-Reductase Inhibitors in In Silico and In Vivo Models
The new compound may be a safer alternative to finasteride for prostate protection.
research MP85-05 SEXUAL DYSFUNCTION AFTER 5-ALPHA REDUCTASE INHIBITOR USE: INSIGHTS FROM THE REDUCE STUDY GROUP DATABASE
Dutasteride use can lead to a stable decline in sexual function that is not affected by age or prostate size.
research Sex differences in clinical trials of ALRV5XR treatment of androgenetic alopecia and telogen effluvium
ALRV5XR effectively promotes hair regrowth in both men and women through different mechanisms.
research Frontal fibrosing alopecia: A retrospective review of 19 patients seen at Duke University
Dutasteride may help stabilize Frontal Fibrosing Alopecia, but more research is needed.
research A Review of Medicinal Uses and Pharmacological Activities of Tridax Procumbens (L.)
Tridax procumbens may be a safe, affordable treatment for some health issues.
research 52811 A comparative study of pain perception during platelet rich plasma therapy using sodium citrate and acid citrate dextrose-A as anticoagulant
Sodium citrate causes less pain than acid citrate dextrose-A in PRP therapy.
research Patient-reported treatment outcomes and safety of direct-to-consumer teledermatology for finasteride treatment in male androgenetic alopecia: A cross-sectional study
Most men using teledermatology for hair loss treatment saw improved hair and self-esteem, with some experiencing side effects.
research Beta-trace protein in chronic inflammatory demyelinating polyradiculoneuropathy and Guillain-Barré syndrome – clinical utilization and a new insight into pathophysiological mechanisms
Beta-trace protein may help diagnose and predict treatment response in certain nerve disorders.
research Treatment of discoid lupus erythematosus scarring alopecia with deucravacitinib: A case report
Deucravacitinib helped regrow hair and reduce plaques in a woman with discoid lupus erythematosus without side effects.
research Glucocorticoids and Risk of Venous Thromboembolism in Asthma Patients Aged 20–59 Years in the United Kingdom’s CPRD 1995–2015
Higher doses of glucocorticoids increase the risk of blood clots in asthma patients.
research Eficacia de la combinación de doxazosina y finasterida en la hipertrofia benigna de próstata
Combining doxazosin and finasteride is more effective for managing benign prostatic hyperplasia than using either drug alone.
research Effect of the frequency of injection on the clinical responses of postmenopausal women to testosterone enanthate with estradiol valerate
Injecting 2 ml of TEEV every 4 weeks is better because it has the same benefits but fewer side effects.
research Sensitive bromatometric assay methods for finasteride in pharmaceuticals
Three methods accurately measure finasteride in tablets using dyes and bromate-bromide.
research There are early, gradual and late responders for scalp hair regrowth in patients with alopecia areata treated with baricitinib
Different people with severe hair loss respond to baricitinib treatment at different times, with some showing improvement early, some gradually, and others later.
research Long-term use of 5α-reductase inhibitors and the risk of male breast cancer
Taking 5α-reductase inhibitors does not significantly increase the risk of breast cancer in men.
research Solubilization and Solid‐State Characterization of a Poorly Soluble 5‐α Reductase Inhibitor
GI197111X is best dissolved in Capmul MCM for trials.
research Mesotherapy with bicalutamide for female pattern hair loss
Mesotherapy with bicalutamide has limited effectiveness for female hair loss.
research Equine 5α-reductase activity and expression in epididymis
The equine epididymis mainly uses type 1 5α-reductase, and both finasteride and dutasteride can inhibit its activity.
research The impact of monotherapies for male androgenetic alopecia: A network meta‐analysis study
"Dutasteride 0.5 mg daily is the most effective treatment for male hair loss."
research 2‐Deoxy‐d ‐glucose enhances tonic inhibition through the neurosteroid‐mediated activation of extrasynaptic GABA A receptors
2-DG reduces seizures by enhancing brain inhibition through specific receptor activation.
research Comparación de los efectos del D-004, imipramina y sertralina en el modelo de nado forzado en ratones Comparative effects of D-004, Imipramine and Sertraline in the forced swimming test in mice
D-004 shows moderate antidepressant effects but is less effective than Sertraline and Imipramine.
research 5α-Reductase inhibitors in androgenetic alopecia
research Topical MK-386 (M), an inhibitor of 5α-reductase (5αr) type I, suppresses sebum dht.
MK-386 reduces sebum DHT levels.
research COMPARATIVE STUDY OF TWO CONCENTRATIONS (2.5MG/ML AND 5 MG/ML) OF INTRALESIONAL TRIAMCINOLONE ACETONIDE IN THE TREATMENT OF ALOPECIA AREATA
2.5 mg/mL TAC is as effective and safe as 5 mg/mL, but 5 mg/mL may improve hair regrowth and density more.
