49 citations
,
January 1991 in “Food and chemical toxicology” Different zinc compounds cause varying levels of skin irritation in animals.
48 citations
,
November 2017 in “Journal of the American Academy of Dermatology” Tofacitinib 2% ointment helped hair regrow in 3 out of 10 patients with alopecia areata, but caused side effects like scalp irritation and raised cholesterol in some.
46 citations
,
December 2010 in “PubMed” Tocotrienol supplements significantly increased hair growth in people with hair loss.
45 citations
,
February 2019 in “Journal of Affective Disorders” Melatonin improved mental health and metabolism in women with PCOS.
45 citations
,
July 2008 in “International Journal of Dermatology” Sulfasalazine may help treat persistent alopecia areata.
44 citations
,
January 2012 in “Food and chemical toxicology” Ursolic acid can shrink the prostate and lower a hormone linked to prostate growth in rats.
44 citations
,
September 1948 in “Radiology” Too much vitamin A can cause serious health problems.
43 citations
,
January 2007 in “American Journal of Clinical Dermatology” Combined minoxidil and tretinoin solution works as well as regular minoxidil for male hair loss.
41 citations
,
April 1997 in “Fertility and sterility” Clomiphene citrate can reverse low hormone levels and symptoms in male runners with hypogonadotropic hypogonadism.
41 citations
,
November 1987 in “British Journal of Dermatology” Ketoconazole cured about 70% of cutaneous leishmaniasis cases caused by Leishmania major.
39 citations
,
July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” FGF and EGF are crucial for hair follicle development and growth.
39 citations
,
January 1991 in “Oncology” High-dose vitamin A was safe and well-tolerated in a lung cancer treatment study.
39 citations
,
January 1977 in “Dermatology” The treatment cleared psoriasis in some patients but caused side effects in most.
37 citations
,
December 2014 in “Journal of Biomedical Informatics” Researchers created LabeledIn, a detailed list of drug uses, showing the importance of human input in making such lists.
37 citations
,
January 2010 in “International Journal of Trichology” Bimatoprost helped eyelash growth in nearly half of the patients with a type of eyelash hair loss.
37 citations
,
September 2002 in “Acta pædiatrica” A cystic fibrosis patient developed Cushing's syndrome from a drug interaction between itraconazole and budesonide, which improved after stopping the medications.
36 citations
,
April 2014 in “Experimental Dermatology” Personalized treatment plans improve vitiligo care.
35 citations
,
December 2009 in “Human reproduction” Metformin taken during pregnancy increases SHBG in newborns but doesn't change other hormone levels in mothers or babies.
33 citations
,
October 2013 in “Journal of The American Academy of Dermatology” Pioglitazone usually doesn't effectively treat or cure lichen planopilaris.
32 citations
,
January 2008 in “Journal of Microencapsulation” Cosmetics with hinokitiol-loaded nanocapsules were found to effectively promote hair growth.
32 citations
,
January 2006 in “Liver transplantation” Vitamin A toxicity can cause severe health issues and may require a liver transplant if other treatments fail.
31 citations
,
January 2019 in “Frontiers in Veterinary Science” Laser therapy improved surgical scar healing in dogs.
31 citations
,
February 1999 in “Dermatologic surgery” Sun exposure after laser hair removal can cause skin darkening, which is hard to treat and requires avoiding UV light.
31 citations
,
February 1983 in “American Journal of Clinical Nutrition” Biotin deficiency can cause hair loss in adults on long-term TPN, but supplementation helps regrow hair.
30 citations
,
September 2003 in “Experimental Dermatology” Minoxidil helps prevent stress-caused hair loss in mice.
30 citations
,
December 1999 in “International Journal of Dermatology” Finasteride increases hair count in middle-aged and elderly men without causing sexual dysfunction.
29 citations
,
January 2004 in “Experimental Dermatology” Topical anthralin helped regrow hair in mice with a condition similar to human alopecia.
29 citations
,
December 2003 in “Teratology” Minoxidil use during pregnancy may cause fetal harm.
29 citations
,
February 2003 in “Journal of Dermatology” Spironolactone may help enlarge a small breast linked to Becker's nevus.
29 citations
,
July 1982 in “British Journal of Dermatology” Lithium treatment can cause increased hair shedding and hair loss in patients.