June 2023 in “Animal Bioscience” Vimentin and transthyretin proteins are linked to black coat color in sheep.
Dermoscopy is useful for diagnosing hair loss patterns in dogs.
29 citations
,
January 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” P-cadherin is crucial for hair follicle pigmentation but not skin pigmentation.
3 citations
,
January 2023 in “Journal of Cutaneous and Aesthetic Surgery” Intradermal PRP significantly improved melasma in dark skin, with lasting results and no relapse after 3 months.
2 citations
,
November 2024 in “JAAD reviews.” Certain drugs can change hair color, either lightening or darkening it.
1 citations
,
June 2025 in “Pigment Cell & Melanoma Research” SASH1 gene mutations are linked to various inherited skin pigmentation disorders.
4 citations
,
February 2022 in “Nutrients” Korean Red Ginseng saponins may protect skin from inflammation and darkening caused by air pollution.
31 citations
,
August 2023 in “Cell Genomics” The Tyrolean Iceman had mostly Anatolian farmer ancestry and traits like darker skin and a risk for certain health issues.
126 citations
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November 1987 in “The Journal of Pediatrics” Selenium deficiency can cause skin and hair color loss, muscle weakness, and blood cell changes, but these improve with selenium supplements.
35 citations
,
October 2003 in “Dermatologic clinics” Laser therapy on darker skin has higher risks and needs expert handling.
3 citations
,
September 2023 in “Stem Cell Research & Therapy” Stem cells can be used to create long-lasting skin cells for treating pigment disorders.
TBX3 gene affects horse coat color, with higher expression in darker areas.
March 2024 in “Indian Journal of Dermatology” The man was diagnosed with Cronkhite-Canada syndrome, a rare disorder with GI polyps, skin issues, hair loss, and nail problems.
March 2011 in “Pigment Cell & Melanoma Research” The Agouti gene influences pigmentation and may have a developmental role in deer mice.
October 2025 in “Journal of Investigative Dermatology” Iron balance is crucial for skin health, affecting conditions like psoriasis and hair loss.
57 citations
,
April 2009 in “Differentiation” SDF-1/CXCL12 and its receptor CXCR4 are crucial for melanocyte movement in mouse hair follicles.
35 citations
,
July 2007 in “Dermatologic clinics” Facial dark spots can be caused by the sun, genetics, makeup, or medicine, and are diagnosed by patient history and skin tests.
31 citations
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November 2015 in “PloS one” Reducing Tyrosinase prevents mature color pigment cells from forming in mouse hair.
12 citations
,
January 2013 in “Indian dermatology online journal” Dermatopathia pigmentosa reticularis causes skin discoloration, hair loss, and nail problems.
10 citations
,
September 2022 in “Journal of Biophotonics” Blue light therapy is safe for skin and may protect against UV radiation.
9 citations
,
January 2013 in “International journal of trichology” 88% phenol is effective for treating alopecia areata.
7 citations
,
January 2021 in “Frontiers in genetics” Inherited color dilution in rabbits is linked to DNA methylation changes.
7 citations
,
June 2012 in “Journal of dairy science” Bovine milk fats applied to mouse skin can promote hair growth similar to known hair growth treatments.
5 citations
,
January 2023 in “International Journal of Molecular Sciences” Hair follicles could be used to noninvasively monitor our body's internal clock and help identify risks for related diseases.
4 citations
,
May 2018 in “International Journal of Molecular Sciences” The research showed how melanocytes develop, move, and respond to UV light, and their stem cells' role in hair color and skin cancer risk.
3 citations
,
November 2022 in “Experimental dermatology” Melatonin may inhibit melanoma growth and has potential as a cancer therapy aid, but its effects on human skin pigmentation need more research.
2 citations
,
December 2025 in “Cosmetics” Proper scalp care can improve hair health and delay ageing signs.
1 citations
,
September 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Skin organoids from stem cells can help study and treat skin issues but face some challenges.
Hair can naturally regain color after greying, and this change may be linked to stress levels.
September 2025 in “The Open Dermatology Journal” The AI showed high accuracy in diagnosing skin conditions but needs improvement for immunological and infectious disorders.