research Dermal Adipocyte Lipolysis and Myofibroblast Conversion Are Required for Efficient Skin Repair
Fat cells in the skin help start healing and form important repair cells after injury.
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540-570 / 1000+ results research Changes in Different Melanocyte Populations During Hair Follicle Involution (Catagen)
Different melanocyte types in hair follicles either survive or die during the catagen phase.
research Engineering a 3D wounded skin equivalent to study early inflammatory and regenerative responses in vitro
A 3D skin model helps study wound healing better than traditional methods.
research Effect of 5α-Dihydrotestosterone and Testosterone on Apoptosis in Human Dermal Papilla Cells
High levels of testosterone and 5α-DHT can lead to cell death in cells important for hair growth.
research Cell-repellent polyampholyte for conformal coating on microstructures
Prevelex, a polyampholyte, can create a cell-repellent coating on microdevices, which can be useful in biomedical applications like hair follicle regeneration.
research Accelerated Endothelial to Mesenchymal Transition Increased Fibrosis via Deleting Notch Signaling in Wound Vasculature
Disrupting Notch signaling in blood vessels increases scarring during wound healing in mice.
research HDAC1-Overexpressing Dermal Papilla Cell-Derived Extracellular Vesicles Modulate p53 and Wnt/β-Catenin Signaling to Rescue Hair Follicle Regeneration in Androgenetic Alopecia
research Features of Irradiated Skeletal Muscle on Mohs Frozen Section Examination
research Glycyrrhizic acid attenuates stem cell-like phenotypes of human dermal papilla cells
Glycyrrhizic acid may help reduce unwanted hair growth.
research Ultrasound-ActivatedGelMA Hydrogel Loaded with MSC-EVsPromotes Functional Regeneration of Skin Vasculature, Nerves, andAppendages
Ultrasound and GelMA hydrogel with stem cell vesicles improve skin healing and regeneration.
research Skin Cyst: A Pathological Dead-End With a New Twist of Morphogenetic Potentials in Organoid Cultures
Skin cysts might help advance stem cell treatments to repair skin.
research 250 Sweat glands shrink upward with aging, causing dermal layer defects that lead to loss of skin elasticity and wrinkling-establishment of 3D imaging method for skin appendages
Aging causes sweat glands to shrink and move upward, leading to less elastic skin and more wrinkles.
research Mediator 1 ablation induces enamel-to-hair lineage conversion in mice through enhancer dynamics
Removing Mediator 1 from certain mouse cells causes teeth to grow hair instead of enamel.
research The blastema and epimorphic regeneration in mammals
Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.
research [Effect of deep dermal tissue dislocation injury on skin fibrosis in pig].
Deep dermal tissue dislocation injury in pigs leads to thicker fibrotic tissue and increased type III collagen, affecting skin repair.
research Extracellular proteoglycan decorin maintains human hair follicle stem cells
Decorin helps keep hair follicle stem cells and may prevent age-related hair loss.
research Rapid mechanosensitive migration and dispersal of newly divided mesenchymal cells aid their recruitment into dermal condensates
Newly divided skin cells quickly move to join skin structures due to tissue tension and specific signals.
research Hair Follicle Apoptosis and Bcl-2
research Fat transplant: Amazing growth and regeneration of cells and rebirth with the miracle of fat cells
Fat transplants using a patient's own fat can rejuvenate and repair tissues effectively.
research Major Improvement in Wound Healing Through Pharmacologic Mobilization of Stem Cells in Severely Diabetic Rats
A new therapy sped up wound healing and reduced scarring in diabetic rats.
research Chapter 3 Expression and Modification of Keratins During Terminal Differentiation of Mammalian Epidermis
Keratins change and are modified differently in skin layers and body parts.
research Hair follicle dermal cells differentiate into adipogenic and osteogenic lineages
Hair follicle cells can become fat and bone cells.
research Biomimetic Scaffolds—A Novel Approach to Three Dimensional Cell Culture Techniques for Potential Implementation in Tissue Engineering
Biomimetic scaffolds are better than traditional methods for growing cells and could help regenerate various tissues.
research Chemically induced transformation of human dermal fibroblasts to hair‐inducing dermal papilla‐like cells
Researchers found a way to turn skin cells into cells that can grow new hair.
research Homeodynamic Rejuvenation: an adaptive framework for resetting skin aging
The article introduces Homeodynamic Rejuvenation as a framework for addressing skin aging by restoring the skin's ability to manage stress and recover efficiently, rather than merely reversing visible signs of aging. This approach emphasizes homeodynamic plasticity, which is the skin's capacity to maintain function under stress. It integrates homeodynamics with exposome biology to reactivate cellular systems responsible for stress sensing, repair, and recovery. Five core processes—intracellular quality control, regenerative competence, metabolic resilience, cellular integrity, and structural integrity—are crucial for maintaining skin function. Disruption of these processes leads to skin aging, with dermatoporosis as a severe outcome. Homeodynamic Rejuvenation is evaluated through dynamic perturbation–recovery kinetics, linking biological processes to functional and clinical outcomes, thus providing a framework for enhancing skin resilience.
research Cellular activation pathways and interaction networks in vascularized composite allotransplantation
Understanding cellular interactions in VCA may lead to better treatments and reduce rejection.
research 1340 Basal keratinocytes exhibit age-related epigenetic and transcriptomic alterations resulting in an altered metabolic profile
Aging changes skin cells, leading to different DNA methylation and gene activity, affecting cell metabolism and aging signs.
research Hair multiplication with dermal papilla like tissue containing human dermal papilla cells
Injecting lab-grown hair cells into the scalp can regrow hair.
research Parallels in signaling between development and regeneration in ectodermal organs
research 1314 Advanced age impairs self-renewal and biases fate choice of hair follicle dermal stem cells
Older hair follicle stem cells have a reduced ability to renew themselves, leading to more hair loss.