research Analysis of the microRNA expression profile of normal human dermal papilla cells treated with 5α-dihydrotestosterone
DHT affects hair follicle cells by changing microRNA levels, leading to less cell growth and more cell death.
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780-810 / 1000+ results research Progressive Hair Loss and Myocardial Degeneration in Rough Coat Mice: Reduced Lysyl Oxidase-Like (LOXL) in the Skin and Heart
The gene causing hair loss and heart issues in rough coat mice is still unknown.
research Relapse of hirsutism following long‐term successful treatment with oestrogen–progestogen combination
Most patients experienced hirsutism again after stopping hormone treatment, indicating long-term treatment is needed to maintain results.
research Change of the diagnostic distribution in applicants to dermatology after COVID ‐19 pandemic: What it whispers to us?
The COVID-19 pandemic led to fewer dermatology visits and changed the types of skin conditions patients experienced.
research Hair growth potential of Salvia plebeia extract and its associated mechanisms
Salvia plebeia extract can stimulate hair growth.
research Results of scalp cooling during anthracycline containing chemotherapy depend on scalp skin temperature
Cooler scalp temperatures during chemotherapy may prevent hair loss.
research Expression of matrix metalloproteinases and tissue inhibitor of matrix metalloproteinases in the hair cycle
MMP-2 and MMP-9 help hair grow, while their inhibitors peak when hair growth slows.
research Long-term control of epileptic drop attacks with the combination of valproate, lamotrigine, and a benzodiazepine: A ‘proof of concept,’ open label study
The drug combination significantly reduced epileptic drop attacks in patients.
research The stumptailed macaque as a model for androgenetic alopecia: Effects of topical minoxidil analyzed by use of the folliculogram
The study used monkeys to test a hair loss treatment called minoxidil, which showed positive results.
research Novel aspects of age-protection by spermidine supplementation are associated with preserved telomere length
Spermidine helps protect against aging by preserving telomere length.
research Alteration of Skin Wound Healing in Keratinocyte-Specific Mediator Complex Subunit 1 Null Mice
MED1 affects skin wound healing differently in young and old mice.
research Investigation of aging effects in human hair using atomic force microscopy
Aging makes hair thinner and rougher, with less clear edges.
research The effect of canakinumab on clinical outcomes in patients with COVID-19: A meta-analysis
Canakinumab's effect on COVID-19 outcomes is unclear.
research The circular RNA circNlgnmediates doxorubicin-inducedcardiac remodeling and fibrosis
A specific RNA, circNlgn, contributes to heart damage and scarring caused by the cancer drug doxorubicin.
research The effect of finasteride and dutasteride on the synthesis of neurosteroids by glioblastoma cells
Finasteride and dutasteride reduce neurosteroid production, possibly helping treat glioblastoma.
research A computational modelling framework to quantify the effects of passaging cell lines
Cell characteristics change with passage numbers, affecting experiment results.
research Analysis of hair follicle penetration of lidocaine and fluorescein isothiocyanate-dextran 4 kDa using hair follicle-plugging method
Hair follicles are important for the absorption of certain drugs into the skin.
research Novel modulatory effects of neurosteroids and benzodiazepines on excitatory and inhibitory neurons excitability: a multi-electrode array recording study
Neurosteroids and benzodiazepines reduce neuron excitability, with lasting effects on inhibitory neurons.
research Enhanced Sensitivity to Ethanol-Induced Inhibition of LTP in CA1 Pyramidal Neurons of Socially Isolated C57BL/6J Mice: Role of Neurosteroids
Social isolation makes mice more sensitive to alcohol's effects on brain function.
research ToF‐SIMS characterization of the lipid layer on the hair surface. II : Effect of the 18‐MEA lipid layer on surface hydrophobicity
18-MEA is essential for hair's water resistance, and a conditioner with 18-MEA and SPDA can restore it.
research Severe Hypertension in Children With Renal Disease: Treatment With Minoxidil
Minoxidil lowers blood pressure in kids with kidney issues, but use carefully due to side effects.
research Public interest in dermatologic symptoms, conditions, treatments, and procedures during the COVID‐19 pandemic: Insights from Google Trends
Public interest in skin issues changed during COVID-19, with more focus on dry skin, hair problems, and hand eczema.
research An investigation of crosstalk between Wnt/β-catenin and transforming growth factor-β signaling in androgenetic alopecia
Wnt/β-catenin and TGF-β pathways affect hair loss, and activating Wnt/β-catenin could be a potential treatment.
research Exposure of Xenopus laevis tadpoles to finasteride, an inhibitor of 5-α reductase activity, impairs spermatogenesis and alters hypophyseal feedback mechanisms
Finasteride exposure harms tadpole reproduction and hormone balance.
research Mechanism of Salutary Effects of Finasteride on Post-traumatic Immune/Inflammatory Response
Finasteride reduces inflammation and improves immune response after trauma by altering hormone levels.
research Low-dose (2.5 mg/day) finasteride treatment in hirsutism
Low-dose finasteride effectively reduces hirsutism without serious side-effects.
research Minoxidil overdose with ecg changes: Case report and review
Minoxidil overdose caused heart changes, treated with stomach wash, charcoal, and IV fluids.
research The probable destructive mechanisms behind COVID-19 on male reproduction system and fertility
COVID-19 may harm male fertility and damage the reproductive system.
research Alterations of gut microbiota composition in post-finasteride patients: a pilot study
Post-finasteride patients show changes in gut bacteria, possibly causing various symptoms.
research AKR1D1 regulates glucocorticoid availability and glucocorticoid receptor activation in human hepatoma cells
AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.