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The FDA did not approve a testosterone drug because of safety concerns.

Gender-affirming hormone therapy improves physical performance in trans men to the level of cisgender men, while in trans women, it increases fat mass and decreases muscle mass, with no advantage in physical performance after 2 years.

Androgens, male hormones, affect physical and mental functions, with a decrease leading to health issues like muscle loss, bone disease, and depression, and more research is needed on long-term effects and treatments.

Going to bed late may increase hormones and decrease muscle in women with PCOS.

Androgens increase muscle mass by promoting myoblast growth through ornithine decarboxylase.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

Testosterone replacement therapy improves libido, mood, muscle strength, and bone density in men with Testosterone Deficiency Syndrome.

Finasteride caused long-term sexual and non-sexual side effects in young men with hair loss.

Rehabilitation therapy helped a severe COVID-19 patient regain muscle mass and return to normal life.

Androgens and SARMs play a role in body mass, frailty, skin health, and hair growth, and are used in treating prostate cancer, acne, and hair loss, with potential for new uses and improved versions in the future.

The body's change of testosterone into DHT is not necessary for testosterone's muscle and sexual effects.

Testosterone works in different ways, including direct interaction with its receptor, conversion to other hormones for specific effects on genitalia, hair, bones, and muscle, and changes in body fat and sexual function when low.

An ovarian tumor caused a woman's male-like symptoms, which improved after surgery.

Men's fertility and sexual health decline with age, with reduced testosterone and virility, and many lose fertility by their eighties.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Ongoing follow-up and dietary counseling are crucial for maintaining health benefits after metabolic surgery.

Testosterone therapy can help postmenopausal women with low sexual desire but needs more safety research and should be used with estrogen therapy.

Lower lipin 1β in belly fat is linked to insulin resistance in people with polycystic ovary syndrome.

Testosterone's muscle-building effects do not require its conversion to DHT.

Estrogen deficiency can reduce the enzyme activity needed to activate vitamin D.

Eating cream can increase ovarian androgen production in women with Polycystic Ovary Syndrome, which is not related to obesity.

High levels of fatty acids are linked to increased androgen production and inflammation in women with PCOS, which may affect IVF outcomes.

Testosterone supplements can increase muscle mass and strength in older men with low levels, but long-term effects and risks need more research.

Enobosarm significantly increased muscle mass and improved physical function in elderly men and postmenopausal women without serious side effects.

Resistance training might help with PCOS symptoms, but more research is needed.

Androgens affect many aspects of female health, and more research is needed to understand their roles and treatment potential.

Testosterone therapy can help with androgen deficiency in women but should be used with caution and monitoring due to potential risks.

Testosterone therapy may improve mood, well-being, and sexual function in premenopausal women, but more research is needed on its long-term safety and effectiveness.

Testosterone and dihydrotestosterone have similar effects on body composition and metabolic health in men.

Corticosteroids, especially prednisone, improve short-term muscle strength in Duchenne muscular dystrophy but have manageable side effects.