research The Notch Intracellular Domain Has an RBPj-Independent Role during Mouse Hair Follicular Development
The Notch signaling pathway helps in mouse hair development through a noncanonical mechanism that does not rely on RBPj or transcription.
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research Molecular Basis for Hair Loss in Mice Carrying a Novel Nonsense Mutation (Hrrh-R) in the Hairless Gene (Hr)
A new mutation in the hairless gene causes hair loss and skin wrinkling in mice.
research An overview of management of drug-induced hair and nail disorders
Cooling the scalp may prevent hair loss from chemotherapy, hair often grows back after treatment, and nail issues usually improve after stopping the drug.
research Epigenetic orchestration of RNA m6A methylation in wound healing and post-wound events
m6A methylation is crucial for proper wound healing and tissue repair.
research Revisiting the significance of keratin expression in complex epithelia
Keratin gene expression helps understand different types of skin cells and their development, and should be used carefully as biological markers.
research Proteomics Characterization of Primary Human Oral Epithelial Cells Using a Novel Culture Technique for Use in Tissue Regeneration
ePUKs could be valuable for regenerative medicine due to their wound healing abilities.
research Tcf3 and Lef1 regulate lineage differentiation of multipotent stem cells in skin
Tcf3 and Lef1 are key in deciding skin stem cell roles.
research Targeted Knockout of β-Catenin in Adult Melanocyte Stem Cells Using a Mouse Line, Dct::CreERT2, Results in Disrupted Stem Cell Renewal and Pigmentation Defects
Removing β-catenin in certain stem cells causes hair whitening and pigmentation issues.
research Vitamin A resolves lineage plasticity to orchestrate stem cell lineage choices
Vitamin A helps skin stem cells decide their function, aiding in hair growth and wound repair.
research The patch assay reconstitutes mature hair follicles by culture-expanded human cells
The patch assay can create mature hair follicles from human cells and may help in hair loss treatments.
research Evidence that mirex promotes a unique population of epidermal cells that cannot be distinguished by their mutant Ha-ras genotype
Mirex seems to promote a unique group of skin cells different from those affected by another tumor promoter, TPA.
research In vitro Differentiation of Hair Follicle Stem Cell into Keratinocyte by Simvastatin
Simvastatin helps hair follicle stem cells turn into skin cells.
research A matter of life and death: self‐renewal in stem cells
Stem cell self-renewal is complex and needs more research for full understanding.
research Beyond acne: Current aspects of sebaceous gland biology and function
The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.
research JunB defines functional and structural integrity of the epidermo-pilosebaceous unit in the skin
JunB is crucial for maintaining healthy skin and hair follicles.
research Androgens modulate keratinocyte differentiation indirectly through enhancing growth factor production from dermal fibroblasts
Male hormones indirectly affect skin cell development by increasing growth factor levels from skin fibroblasts.
research Effects of the selective TrkA agonist gambogic amide on pigmentation and growth of human hair follicles in vitro
Gambogic Amide helps maintain hair color and promotes hair growth.
research Nuclear Topology, Epigenetics, and Keratinocyte Differentiation
Nuclear shape and chromatin changes affect gene expression in skin cell differentiation.
research Characterisation of CD4+ stem cells of the skin and their role in skin homeostasis and tumourigenesis
CD4+ skin cells may be precursors to basal cell carcinoma.
research Understanding Cancer Cells of Origin in Cutaneous Tumors
The document concludes that identifying the specific cells where skin cancers begin is important for creating better prevention, detection, and treatment methods.
research Basal cells in the epidermis and epidermal differentiation
The exact identity of skin stem cells and how skin cells differentiate is not fully known.
research Human hair follicle organ culture: theory, application and perspectives
Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.
research DNMT1-mediated methylation inhibits microRNA-214-3p and promotes hair follicle stem cell differentiate into adipogenic lineages
DNMT1 helps turn hair follicle stem cells into fat cells by blocking a specific microRNA.
research 1372 Biological effects of electrical epilation on human hair follicles and perifollicular skin ex vivo
Electrical epilation damages hair follicles and surrounding skin, likely preventing hair regrowth.
research ATP-dependent chromatin remodeling during mammalian development
ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.
research Enrichment for Living Murine Keratinocytes from the Hair Follicle Bulge with the Cell Surface Marker CD34
CD34 is a marker for isolating stem-like cells in mouse hair follicles.
research JMJD3 and NF-κB-dependent activation of Notch1 gene is required for keratinocyte migration during skin wound healing
JMJD3 and NF-κB activate Notch1, which is essential for skin cell movement and wound healing.
research The Expression of Vitamin D-Upregulated Protein 1 in Skin and its Interaction with Sciellin in Cultured Keratinocytes
VDUP1 is found in skin and hair follicles, interacts with sciellin, and may help regulate skin cell differentiation.
research Oral Combination Treatment of Gefitinib (IressaTM) and Sasam-Kyeongokgo: Synergistic Effects on the NCI-H520 Tumor Cell Line
Gefitinib and Sasam-Kyeongokgo together significantly reduce cancer growth and improve immune response in mice.
research There and Back Again: Hair Follicle Stem Cell Dynamics
Hair follicle stem cells can return to their original niche and help regenerate hair.