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research Inhibition of the development of metastatic squamous cell carcinoma in protein kinase C epsilon transgenic mice by alpha-difluoromethylornithine accompanied by marked hair follicle degeneration and hair loss.

26 citations , June 2003 in “PubMed”

Alpha-difluoromethylornithine prevents cancer in mice but causes hair loss.

research Finasteride may increase risk of seizures

October 2014 in “Reactions Weekly”

research 5α‐reductase inhibitors: Evaluation of their potential confounding effect on GC‐C‐IRMS doping analysis

3 citations , July 2021 in “Drug Testing and Analysis”

5α-reductase inhibitors can interfere with doping tests by masking banned substances.

Pegylated-Interferon-Alpha 2a in Clinical Practice: How to Manage Patients Suffering from Side Effects

research Pegylated-interferon-α_2ain clinical practice: how to manage patients suffering from side effects

17 citations , February 2011 in “Expert Opinion on Drug Safety”

Manage side effects of hepatitis C treatment with dose changes and medications, which may improve patient adherence and treatment success.

research Effects of Finasteride (MK-906), a 5α-Reductase Inhibitor, on Circulating Androgens in Male Volunteers*

147 citations , April 1990 in “The Journal of Clinical Endocrinology and Metabolism”

Finasteride safely lowers DHT levels without affecting testosterone.

Safety and Efficacy of a Topical Treatment (SM04554) for Androgenetic Alopecia: Results from a Phase 1 Trial

research Safety and efficacy of a topical treatment (SM04554) for androgenetic alopecia (AGA): Results from a phase 1 Trial

2 citations , April 2016 in “Journal of The American Academy of Dermatology”

Dutasteride more effective than finasteride for hair growth; SM04554 safe and potentially effective for hair loss.

research Frontal fibrosing alopecia: demographic and clinical characteristics of 490 cases

53 citations , June 2019 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology”

Frontal fibrosing alopecia mainly affects postmenopausal women and may be linked to thyroid hormones.

research 12 Treatment of hirsutism with 5α-reductase inhibitors

28 citations , May 1986 in “Clinics in endocrinology and metabolism”

New compounds may soon be tested to treat excessive hair growth in women.

research Effects of 5‐alpha reductase inhibitors on lung function: A reason for discontinuation duringCOVID‐19 pandemic?

5 citations , May 2020 in “Dermatologic Therapy”

5-alpha reductase inhibitors might worsen lung recovery in COVID-19 patients, suggesting a pause in their use.

research 5α‐Reductase Inhibitors

September 2014

5-Alpha reductase inhibitors help treat enlarged prostate but may cause sexual side effects.

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