research CRISPR/Cas9-mediated Generation ofCOL7A1-deficient Keratinocyte Model of Recessive Dystrophic Epidermolysis Bullosa
Scientists created cell lines to study a genetic skin disorder using CRISPR technology.
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960-990 / 1000+ resultsresearch Metabolite identification by mass spectrometry of the 5α-reductase inhibitor finasteride in vitro and in vivo
Finasteride's metabolites were identified, helping understand how the drug is processed in the body.
research Biodegradable Polysaccharide Gels for Skin Scaffolds
Biodegradable polysaccharide gels can improve skin healing and reduce scarring.
research Human hair shaft proteomic profiling: individual differences, site specificity and cuticle analysis
Human hair proteins vary by individual, body site, and ethnicity, useful for forensics.
research Eficacia del tratamiento con inyecciones intradérmicas de plasma rico en plaquetas para la alopecia androgenética en varones: estudio de «antes-después»
PRP injections increased hair density in men with hair loss but didn't work for everyone and more research is needed.
research Oxidative Stress and Hormone-regulated Dermal Papilla Cell-targeted Nanomodulators: Reverse Cellular Senescence for Androgenetic Alopecia Therapy
Targeted nanomodulators can rejuvenate cells and promote hair growth in androgenetic alopecia.
research The Mixed Lineage Kinase Leucine-Zipper Protein Kinase Exhibits a Differentiation-Associated Localization in Normal Human Skin and Induces Keratinocyte Differentiation upon Overexpression
ZPK helps skin cells mature and may affect skin health.
research Trichohyalin: Purification from Porcine Tongue Epithelium and Characterization of the Native Protein
research [Changes in trace elements (zinc, copper and manganese) in the hair before and after severe fractures by proton-induced X-ray emission spectrometry (PIXE)].
research Comparative Gene Expression Profiling of Senescent and Androgenetic Alopecia Using Microarray Analysis
SA linked to mitochondrial issues and oxidative stress, while AGA involves disrupted hair growth genes.
research Composition, structural features, and multifunctional properties of extracellular polysaccharides from the non-toxic green alga Parachlorella sp.
The green alga Parachlorella sp. has potential for use in cosmetics and health products due to its antioxidant, anti-hypertensive, and hair growth properties.
research Epithelial-to-Mesenchymal Stem Cell Transition in a Human Organ: Lessons from Lichen Planopilaris
PPAR-γ agonists like pioglitazone may help manage lichen planopilaris but don't fully reverse scarring.
research Dynamic changes of gut and skin microbiota in pancreatic cancer-induced skin injury
Pancreatic cancer can alter gut and skin bacteria, possibly causing skin issues.
research Princípios ativos e procedimentos na Alopecia Androgenética
The review found that PRP is the most effective treatment for hair loss with few side effects.
research High-resolution structures of mutants of residues that affect access to the ligand-binding cavity of human lipocalin-type prostaglandin D synthase
Mutations in the enzyme don't significantly change how it binds to its specific substances.
research PPAR-γ Agonists and Their Role in Primary Cicatricial Alopecia
PPAR-γ helps control skin oil glands and inflammation, and its disruption can cause hair loss diseases.
research Activation of Polyamine Catabolism Profoundly Alters Tissue Polyamine Pools and Affects Hair Growth and Female Fertility in Transgenic Mice Overexpressing Spermidine/SpermineN 1-Acetyltransferase
Overexpressing a specific enzyme in mice causes hair loss and female infertility.
research Making the head: Caspases in life and death
Caspases are enzymes important for both cell death and various non-lethal cell functions, affecting head development and hair growth, with different caspases playing specific roles.
research Androgen Receptor Accelerates Premature Senescence of Human Dermal Papilla Cells in Association with DNA Damage
Androgen receptor signaling causes early aging of cells important for hair growth by damaging their DNA.
research 474 Stabilizing mutations of KLHL24 ubiquitin ligase cause loss of keratin 14 and human skin fragility
Certain mutations in the KLHL24 gene cause a skin disorder by breaking down an important skin protein.
research The stratum corneum barrier: impaired function in relation to associated lipids and proteins
The skin's outer layer relies on lipids and proteins to protect against damage.
research 1330 The possible role of PTEN-induced kinase 1-mediated mitophagy by regulating inflammasome activation in the pathogenesis of alopecia areata
Activating mitophagy may help manage a key immune response involved in the hair loss condition alopecia areata.
research Keratin-modified waterborne polyurethane: an alternative circular economy technology for adding value to cattle hair waste from leather tanneries
research Cytokine Profiling in Primary Cicatricial Alopecia: Androgenic Alopecia and Leptin Connections
Certain inflammatory molecules and leptin may contribute to hair loss in cicatricial alopecia.
research Loss of a homologous group of proteins in a dominantly inherited ectodermal malformation
Naked-mouse hair lacks certain proteins and has less soluble fibril.
research ASSISTÊNCIA DE ENFERMAGEM À POPULAÇÃO TRANSEXUAL
research Circulating androgen regulation by androgen-catabolizing gut bacteria in male mouse gut
Gut bacteria can lower androgen levels in male mice.
research 1. 2年間の低負荷レジスタンストレーニングが高齢者の筋機能に及ぼす効果(第134回日本体力医学会関東地方会)
Blocking 5α-reductase can reduce sleep deprivation-related behavioral issues in rats.
research Effects of combined use of keratinolytic enzymes and sugarcane fibre on the hairball excretion in cats
Combining sugarcane fiber and enzymes reduces hairballs in cats.
research 1380 PPAR-γ modulation as a novel therapeutic strategy for scarring alopecia
A new treatment using AGED to modulate PPAR-γ shows promise for treating scarring hair loss by protecting and repairing hair follicle cells.