research Maternal Melatonin Contributes to Offspring Hair Follicle Development Through Transcriptional Regulation of the AP-1 Complex and MAPK Pathway
Maternal melatonin improves offspring hair growth by affecting specific proteins and pathways.
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research Formulation and Evaluation of Nanogel Containing Quercetin for Treatment of Alopecia
Quercetin-loaded nanogels show promise for treating alopecia effectively.
research Effects of Camellia oleifera seed shell polyphenols and 1,3,6-tri-O-galloylglucose on androgenic alopecia via inhibiting 5a-reductase and regulating Wnt/β-catenin pathway
Camellia oleifera seed shell polyphenols and 1,3,6-tri-O-galloylglucose can help treat hair loss by reducing certain hormones and promoting hair growth.
research Aromatherapy for Unifocal Alopecia Areata and Dermatitis: A Case Report
Essential oils like lavender, chamomile, and bergamot help manage stress and improve well-being.
research Rps14 upregulation promotes inner ear progenitor proliferation and hair cell regeneration in the neonatal mouse cochlea
Increasing Rps14 helps grow more inner ear cells and repair hearing cells in baby mice.
research Formulation, Development and Evaluation of Invasomes Loaded Clotrimazole Gel for Fungal Treatment
Invasomes loaded with clotrimazole gel could improve drug delivery through the skin for fungal treatment.
research New frontiers in CRISPR/Cas9 delivery systems delivery for gene editing
Efficient delivery systems are needed for the clinical use of CRISPR-Cas9 gene editing.
research Phytochemicals as emerging therapeutic agents for alopecia treatment
Plant-based chemicals may help hair growth and prevent hair loss but need more research to compete with current treatments.
research News in brief
Scientists found key proteins and genes that affect skin and hair health, and identified potential new treatments for hair loss, skin disorders, and wound healing.
research Penetration and storage of particles in human skin: Perspectives and safety aspects
Particles around 100 nm can penetrate and stay in hair follicles without passing through healthy skin, making them safe for use in topical products and useful for targeted drug delivery.
research Nonclassic congenital adrenal hyperplasia
Nonclassic congenital adrenal hyperplasia is a genetic disorder causing hormone imbalances, affecting fertility and requiring personalized treatment.
research New drugs under investigation for the treatment of alopecias
New treatments for hair loss show promise, but more research is needed to confirm their safety and effectiveness.
research Formulation-by-Design of Efinaconazole Spanlastic Nanovesicles for Transungual Delivery Using Statistical Risk Management and Multivariate Analytical Techniques
Spanlastic nanovesicles can improve efinaconazole delivery through nails.
research Formulation of Sodium Valproate Nanospanlastics as a Promising Approach for Drug Repurposing in the Treatment of Androgenic Alopecia
Sodium Valproate nanospanlastics could be a safe and effective treatment for Androgenic Alopecia, with fewer side effects than minoxidil.
research A medicinal and edible formula YH0618 ameliorates the toxicity induced by Doxorubicin via regulating the expression of Bax/Bcl-2 and FOXO4
The formula YH0618 can reduce the harmful side effects of the chemotherapy drug Doxorubicin and protect healthy cells.
research The Notch Intracellular Domain Has an RBPj-Independent Role during Mouse Hair Follicular Development
The Notch signaling pathway helps in mouse hair development through a noncanonical mechanism that does not rely on RBPj or transcription.
research Early-stage bilayer tissue-engineered skin substitute formed by adult skin progenitor cells produces an improved skin structure in vivo
Adult skin cell-based early-stage skin substitutes improve wound healing and hair growth in mice.
research Alopecia - the search for novel agents continues
Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.
research Proposed mechanisms of low-level light therapy in the treatment of androgenetic alopecia
LLLT helps treat hair loss by increasing blood flow, reducing inflammation, and stimulating growth factors.
research The G1/S transition in mammalian stem cells in vivo is autonomously regulated by cell size
Cell size controls when stem cells divide.
research 601 Hair growth properties of Cinchona succirubra Extract, Leontopodium alpinum Extract and Manganese PCA in human hair follicle dermal papilla cells
The ingredients could help prevent hair loss by promoting hair growth and increasing VEGF secretion.
research Nevoid basal carcinoma syndrome (Gorlin syndrome) and pronounced androgenic alopecia in a woman with a novel mutation p.Leu1159fsx32 in the PTCH gene
A woman with a new PTCH gene mutation has both Gorlin syndrome and severe hair loss.
research Exosomes derived from mouse vibrissa dermal papilla cells promote hair follicle regeneration during wound healing by activating Wnt/β-catenin signaling pathway
Mouse cell exosomes help hair regrowth and wound healing by activating a specific signaling pathway.
research HDL as Therapeutic Tools
Modified HDL can better deliver drugs and genes, potentially improving treatments and reducing side effects.
research Chapter 14 Low-Level Laser Therapy and Stem Cells
Low-level laser therapy may help stem cells grow and function better, aiding in healing and tissue repair.
research Label Retaining Cells (LRCs) with Myoepithelial Characteristic from the Proximal Acinar Region Define Stem Cells in the Sweat Gland
Sweat gland stem cells help maintain glands, aid wound healing, and can regenerate skin structures.
research Japan Strengthens Regenerative Medicine Oversight
Japan improved its regulation of regenerative medicine to ensure safety and prevent unproven treatments.
research From hair to liver: emerging application of hair follicle mesenchymal stem cell transplantation reverses liver cirrhosis by blocking the TGF-β/Smad signaling pathway to inhibit pathological HSC activation
Hair follicle stem cell transplants can reverse liver cirrhosis by blocking harmful cell activation.
research Assessment of retinol-binding protein 4 in patients with alopecia areata and androgenetic alopecia
Higher RBP4 levels found in people with two types of hair loss.
research A Precis of the alopecia (Hair loss) associated with therapies based on nanotechnology and its impact on quality of Life (QoL)
Nanotechnology therapies can help improve quality of life for those with hair loss.