25 citations
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November 2020 in “Cell Reports Medicine” Developing human skin has immune cells with memory-like features.
38 citations
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January 2006 in “Journal of Cellular Biochemistry” Researchers isolated a new type of stem cell from mouse skin that can renew itself and turn into multiple cell types.
128 citations
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August 2020 in “Cell stem cell” Dermal fibroblasts have adjustable roles in wound healing, with specific cells promoting regeneration or scar formation.
November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” The research identified specific genes that are active in the cells crucial for hair growth.
June 2019 in “PRISM (University of Calgary)” DPCs and new biomaterials can greatly improve skin healing.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” Certain immune cells, when activated by specific signals, can encourage hair growth.
April 2017 in “Journal of Investigative Dermatology” Deleting the CRIF1 gene in mice disrupts skin and hair formation, certain proteins affect hair growth, a new compound may improve skin and hair health, blood cell-derived stem cells can create skin-like structures, and hair follicle stem cells come from embryonic cells needing specific signals for development.
20 citations
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December 2013 in “PLoS ONE” β1 integrin is essential for the survival, growth, and movement of human epithelial progenitor cells.
233 citations
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October 2004 in “Differentiation” Stem cells are in deep skin layers, while differentiating cells are in shallow layers.
91 citations
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June 2011 in “The EMBO Journal” TCF/Lef1 activity is essential for proper skin cell development and renewal.
October 2025 in “Journal of Investigative Dermatology” Hair follicle dermal stem cells help control hair growth timing by regulating signals at the hair germ–dermal papilla interface.
September 2019 in “Journal of Investigative Dermatology” Mouse skin fibroblasts vary in function and adaptability based on their environment.
86 citations
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April 2016 in “Nature Communications” Notch1 helps skin heal by attracting specific immune cells.
July 2013 in “University of Southern California Digital Library” New stem cells in nails and sweat glands can regenerate skin and hair.
January 2016 in “British Biotechnology Journal” DP cells can help in hair growth and regenerative medicine.
23 citations
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July 2015 in “PubMed” PDGF and its receptors are crucial for stem cell growth and function.
June 2022 in “Research Square (Research Square)” Nestin-expressing cells turn into a specific type of skin cell in hair follicles during development and in adults.
421 citations
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September 2003 in “Development” Stem cell behavior varies with stimuli, and lineage changes can happen without affecting stem cell division.
March 2026 in “Wound Repair and Regeneration” MARCKSL1 is important for wound healing and could be a target to reduce scarring.
16 citations
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November 2017 in “British Journal of Dermatology” Cells in hair die by breaking down their DNA and mitochondria as they form keratin.
April 2019 in “Journal of Investigative Dermatology” Non-coding RNA boosts retinoic acid production and signaling, aiding regeneration.
24 citations
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February 2006 in “Chinese Medical Journal” Cultured dermal papilla cells can regenerate hair follicles and sustain hair growth.
November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Deleting the CD271 gene in mouse skin cells leads to disorganized skin and increased hair growth, suggesting CD271 is important for skin health.
June 2020 in “Journal of Investigative Dermatology” Tiny particles from skin cells can help activate hair growth.
April 2023 in “Journal of clinical and translational science”
February 2011 in “Journal of Investigative Dermatology” New findings suggest targeting IL-23 could treat psoriasis, skin cells can adapt to new roles, direct conversion of skin cells to blood cells may aid cell therapy, removing certain tumor cells could boost cancer immunotherapy, and melanoma may have many tumorigenic cells, not just cancer stem cells.
45 citations
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May 2003 in “Journal of Cell Science” α3β1-integrin is crucial for maintaining normal hair follicle shape and function but not needed for the development of the surrounding skin.
November 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Apoptotic cells may trigger cell death in hair follicles during their regression cycle.
11 citations
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August 2014 in “PLoS ONE” GFRα2 is essential for controlling neuron size but not for target innervation in certain sensory neurons.
Nipple area expansion in mice needs both pregnancy hormones and mechanical strain.