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GlossaryRepigmentation

process of restoring color to depigmented skin or hair

Repigmentation refers to the process by which color returns to areas of the skin or hair that have lost their natural pigment, often due to conditions like vitiligo or alopecia. This can occur naturally or be induced through treatments such as topical medications, light therapy, or surgical procedures, aiming to restore the normal appearance by stimulating melanocyte activity or transplanting pigment-producing cells.

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research Dermatosurgical techniques for repigmentation of vitiligo

60 citations , April 2006 in “International Journal of Dermatology”

Surgical methods like suction blister grafting and split-thickness skin grafting are highly successful for vitiligo repigmentation, but choosing the right patients is crucial for success.

research Repigmentation of Leukoderma by Minigrafts of Normally Pigmented, Autologous Skin

56 citations , December 1978 in “The Journal of Dermatologic Surgery and Oncology”

Transplanting small skin grafts can successfully repigment leukoderma.

research Repigmentation through Melanocyte Regeneration in Vitiligo

39 citations , March 2017 in “Dermatologic clinics”

UV light can help stimulate the growth of new pigment cells from hair follicles in people with vitiligo.

Clinical Repigmentation Patterns in Pediatric Vitiligo

research Clinical repigmentation patterns in paediatric vitiligo

14 citations , April 2016 in “British Journal of Dermatology”

The study found that the most common repigmentation pattern in children with vitiligo is a combination of patterns, with a new medium spotted pattern identified.

Antroquinonol Exerts Immunosuppressive Effect on CD8+ T Cell Proliferation and Activation to Resist Depigmentation Induced by H2O2

research Antroquinonol Exerts Immunosuppressive Effect on CD8⁺ T Cell Proliferation and Activation to Resist Depigmentation Induced by H₂O₂

11 citations , January 2017 in “Oxidative medicine and cellular longevity”

Antroquinonol may help prevent skin depigmentation by suppressing certain immune cells.

research Transverse Needling After Autologous Mini-Punch Grafts Improves Repigmentation in Stable Non-Segmental Vitiligo

10 citations , July 2021 in “Clinical Cosmetic and Investigational Dermatology”

Combining transverse needling with mini-punch grafts improves vitiligo repigmentation effectively.

research The early repigmentation pattern of vitiligo is related to the source of melanocytes and by the choice of therapy: a retrospective cohort study

6 citations , January 2018 in “International Journal of Dermatology”

Repigmentation patterns in vitiligo depend on melanocyte source, lesion status, and therapy choice.

research Therapeutic effects of topical Mycophenolate mofetil on hydroquinone-induced depigmentation in Guinea pigs and mice

August 2025 in “Annals of Medicine”

Mycophenolate mofetil may safely help restore skin color in depigmentation conditions.

research Chemically Induced Depigmentation of Skin and Hair

January 1990 in “Springer eBooks”

Some chemicals can permanently or temporarily remove color from skin and hair, which can be distressing and is not well-regulated in cosmetics.

research Depigmentation Treatment for Vitiligo

March 2018

Cryotherapy is the best depigmentation method for vitiligo but needs an expert to perform it.

research Cutaneous Sequelae After Burn Injury: Pruritus, Dyspigmentation and Malignancy—Mechanisms and Management

April 2026 in “IntechOpen eBooks”

Burn injuries can cause long-term itching, skin color changes, and cancer risks, needing personalized treatment.

research Medication-Induced Repigmentation of Gray Hair: A Systematic Review

28 citations , December 2019 in “Skin appendage disorders”

Some medications might reverse gray hair, especially those that reduce inflammation or stimulate pigment production, and vitamin B might help.

research A rare repigmentation pattern in a vitiligo patient: a clue to an epidermal stem-cell reservoir of melanocytes?

24 citations , September 2008 in “Clinical and experimental dermatology”

Repigmentation in vitiligo may come from melanocyte stem cells in the skin.

research Repigmentation of hair following adalimumab therapy

17 citations , January 2015 in “Dermatology online journal”

A patient's grey hair regained color during treatment with adalimumab.

research Repigmentation of Leukotrichia Due to Retrograde Migration of Melanocytes After Noncultured Epidermal Suspension Transplantation

17 citations , December 2013 in “Dermatologic Surgery”

The treatment improved hair color in most vitiligo patients without major side effects.

research Repigmentation of Poliosis After Epithelial Grafting for Vitiligo

15 citations , January 2013 in “Dermatologic Surgery”

Epithelial grafting can effectively repigment white hair in vitiligo patients.

research Repigmentation of hair after latanoprost therapy

9 citations , December 2010 in “Journal of The European Academy of Dermatology and Venereology”

Latanoprost therapy potentially caused a woman's white hair to darken again.

research Repigmentation of leukoderma in a piebald patient associated with a novel c-KIT gene mutation, G592E, of the tyrosine kinase domain

6 citations , November 2011 in “Journal of Dermatological Science”

A new gene mutation may allow some piebaldism patients to regain skin color in white patches.

research Repigmentation of Gray Hair After Thyroid Hormone Treatment

6 citations , January 2007 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas”

Gray hair regained color after thyroid hormone treatment.

research Understanding the Mechanism of Repigmentation in Vitiligo

6 citations , October 2006

Understanding repigmentation mechanisms in vitiligo can improve treatments and patient outcomes.

research A Case of Tofacitinib for the Treatment of Resistant Vitiligo and Sustained Repigmentation After Discontinuation

1 citations , January 2023 in “Research Square (Research Square)”

A woman's vitiligo improved with tofacitinib treatment, and her skin color remained even after stopping the medication, but there are concerns about cancer risk.

Repigmentation in Skin of Color After Phenol-Croton Oil Chemical Peel

research Skin of color repigmentation after phenol-croton oil chemical peel

November 2023 in “Journal of the American Academy of Dermatology”

Skin of color can spontaneously repigment after a phenol-croton oil chemical peel.

research Hair Depigmentation Is a Biological Readout for Pharmacological Inhibition of KIT in Mice and Humans

73 citations , October 2003 in “Journal of Pharmacology and Experimental Therapeutics”

Hair color loss can indicate the effectiveness of a drug targeting the KIT protein in mice and humans.

research Pharmacological BACE1 and BACE2 inhibition induces hair depigmentation by inhibiting PMEL17 processing in mice

58 citations , February 2016 in “Scientific reports”

Blocking BACE1 and BACE2 enzymes causes hair color loss in mice.

Fabrication of Polyvinyl Pyrrolidone-K90/Eudragit RL100-Based Dissolving Microneedle Patches Loaded with Alpha-Arbutin and Resveratrol for Skin Depigmentation

research Fabrication of polyvinyl pyrrolidone-K90/Eudragit RL100-based dissolving microneedle patches loaded with alpha-arbutin and resveratrol for skin depigmentation

21 citations , January 2023 in “Biomaterials Science”

Microneedle patches with alpha-arbutin and resveratrol can effectively reduce skin pigmentation without irritation.

research Latanoprost-induced Skin Depigmentation

9 citations , November 2017 in “Journal of Glaucoma”

Latanoprost eye drops may cause skin depigmentation.

Ultraviolet Light-Induced Leukoderma of the Scalp Associated with Androgenetic Alopecia: Senescent Actinic Depigmentation of the Scalp

research Ultraviolet Light-Induced Leukoderma of the Scalp Associated with Androgenetic Alopecia: Senescent Actinic Depigmentation of the Scalp

9 citations , September 2009 in “Journal of Cutaneous Medicine and Surgery”

UV light causes skin color loss in bald areas; wear a cap and use sunscreen.