April 2016 in “Journal of Investigative Dermatology” Sonic hedgehog signaling is needed for the development of touch-receptor cells in the skin, and the loss of Polycomb repressive complex 2 can lead to more of these cells.
10 citations
,
May 2021 in “Psychoneuroendocrinology” Testosterone levels aren't important for depression in men, but some other hormones might affect certain symptoms.
9 citations
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April 2020 in “The Journal of Urology” 5α-Reductase inhibitors don't cause depression.
7 citations
,
January 2019 in “Brazilian Journal of Pharmaceutical Sciences” Maidenhair fern extract reduced anxiety and depression in rats and may work due to its antioxidant and anti-inflammatory properties.
3 citations
,
August 2020 in “Urology Journal” Using 5-alpha reductase inhibitors may increase the risk of mild depression.
3 citations
,
October 2018 in “Journal of Drug Delivery and Therapeutics” People with polycystic ovary syndrome often experience anxiety and depression.
2 citations
,
March 2020 in “Cns & Neurological Disorders-drug Targets” Lurasidone is effective for bipolar depression and schizophrenia, but more safety data is needed.
2 citations
,
July 2019 in “Journal of psychology & clinical psychiatry” Zinc helps reduce the severity of depression.
1 citations
,
March 2023 in “Healthcare” Helping PCOS patients focus on hope and control can reduce depression.
1 citations
,
June 2022 in “International Journal of Health Sciences” Lower BDNF levels link to worse depression in alopecia areata patients.
1 citations
,
January 2022 in “Open Access Macedonian Journal of Medical Sciences” BDNF, TSH, fT4, anti-TPO, and 25-OH Vitamin D levels predict depression risk in patients with autoimmune thyroiditis and hypothyroidism.
1 citations
,
January 2021 in “European Journal of Inflammation” Methylated flavonoids may effectively reduce depression and inflammation caused by finasteride.
1 citations
,
January 2019 Higher testosterone in females with PCOS is linked to depression and cognitive issues, but anti-androgen treatment can help.
1 citations
,
August 2017 in “The Journal of urology/The journal of urology” 5α-reductase inhibitors may increase the risk of depression and suicidal thoughts.
April 2026 in “The Journal of Steroid Biochemistry and Molecular Biology” December 2025 in “Neurobiology of Stress” People who recently attempted suicide during depression showed signs of adrenal fatigue, but had higher DHEA levels around the attempt time.
December 2025 in “Journal of Cosmetic Dermatology” Finasteride does not increase the risk of depression or suicide.
August 2025 in “Journal of Affective Disorders” Gender-diverse people face more depression and anxiety, partly due to stress and lower cortisol levels.
January 2025 in “The Atlantic Journal of Medical Science and Research” Many dermatology patients experience anxiety and depression, especially those with acne or psoriasis.
November 2024 in “Cureus” Combining therapy, behavior techniques, and medication can help manage trichotillomania and depression.
October 2024 in “Journal of Neuroscience Research” Long-term Finasteride treatment reduces depression better than short-term treatment in rats.
May 2024 in “European urology focus” Drugs for prostate enlargement and hair loss were not linked to increased risk of depression or suicide.
Depressed individuals have higher hair sodium and potassium levels, similar to changes seen in astronauts.
Many young women have Polycystic Ovarian Syndrome (PCOS), which is often linked with irregular periods, depression, low self-esteem, and insomnia. Lifestyle and diet changes, along with regular counseling, can help manage these symptoms.
August 2016 in “Psychoneuroendocrinology” April 2022 in “The Journal of Sexual Medicine” Finasteride alone increases suicide risk, but combining it with other treatments reduces this risk.
321 citations
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January 2012 in “Cell stem cell” TGF-β2 helps activate hair follicle stem cells by counteracting BMP signals.
123 citations
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November 2012 in “Stem cells” MicroRNA-302 helps improve the conversion of body cells into stem cells by blocking NR2F2.
60 citations
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May 2018 in “Indian Journal of Psychological Medicine” Women with PCOS often experience anxiety, depression, and a lower quality of life.