November 2003 in “Journal of Dermatology” Authors defend finasteride-depression link, suggest detailed medical history, and call for more investigation.
85 citations
,
August 2018 in “Psychological Medicine” Women with PCOS are more likely to suffer from depression, anxiety, and stress.
69 citations
,
April 2017 in “BMJ open” Many people with alopecia experience high levels of social anxiety, anxiety, and depression, and while wigs can boost confidence, they may also cause anxiety.
49 citations
,
June 2012 in “Anais Brasileiros de Dermatologia” Hair loss in women is linked to higher depression symptoms.
6 citations
,
January 2024 in “Journal of Cosmetic Dermatology” Alopecia areata patients have worse quality of life, anxiety, and depression than vitiligo patients.
5 citations
,
August 2022 in “Psychology Research and Behavior Management” Hair loss in South Saudi Arabia adults often harms quality of life and leads to depression.
2 citations
,
July 2019 in “Digital Showcase Research, Scholarship, & Creative Works (University of Lynchburg)” No proven link between isotretinoin and depression.
1 citations
,
June 2025 in “European Journal of Clinical Pharmacology” Finasteride may increase the risk of suicidality and depression, especially in younger people.
1 citations
,
April 2019 in “The Journal of urology/The journal of urology” Marijuana use is linked to higher chances of needing treatment for urinary symptoms in men over 40.
February 2026 in “Postgraduate Medicine” 5-alpha reductase inhibitors slightly increase depression risk, but the risk varies based on the control group used.
Gender-diverse individuals face more depression and anxiety, possibly due to unique stress profiles.
January 2026 in “Cronfa (Swansea University)” Finasteride and dutasteride may increase the risk of depression and suicidality, so patients should be monitored closely.
August 2025 in “Journal of Affective Disorders” Gender-diverse people face more depression and anxiety, partly due to stress and lower cortisol levels.
August 2025 in “medRxiv (Cold Spring Harbor Laboratory)” 5-alpha reductase inhibitors may increase depression risk by 31%, but results vary based on comparison groups.
June 2025 in “Reactions Weekly” Finasteride may increase the risk of depression and suicidal thoughts.
November 2024 in “SKIN The Journal of Cutaneous Medicine” Patients with anxiety or depression report more severe alopecia areata.
May 2024 in “International journal of medicine and psychology.” Depression worsens eczema severity, increases inflammation, and lowers quality of life.
Many women with PCOS in Saudi Arabia suffer from depression and anxiety.
Men with depression and marijuana usage are more likely to be treated for lower urinary tract symptoms/benign prostatic hyperplasia.
February 2022 in “Journal of Clinical and Experimental Investigations” People with Fibromyalgia Syndrome often have skin symptoms, which can worsen their quality of life and increase depression.
January 2016 in “International Journal of Medical Research and Health Sciences” People with hair loss conditions like Telogen Effluvium and Alopecia Areata often feel scalp pain and are more likely to have anxiety, but not necessarily depression.
October 2010 in “Journal of Men's Health” Some patients may experience lasting sexual dysfunction, depression, and other side effects from 5α-reductase inhibitor therapy.
October 1971 in “The BMJ” Hair loss can be linked to hormonal changes, and physical conditions like heart defects can cause depression.
December 2022 in “JAMA network open” 5α-Reductase inhibitors may increase depression risk but not dementia or suicide.
April 2021 in “Reactions Weekly” Finasteride increases risk of depression, possibly suicidal thoughts, and sexual dysfunction.
37 citations
,
January 2019 in “JAMA Dermatology” People with Major Depressive Disorder have a higher chance of getting Alopecia Areata, and vice versa; antidepressants may lower this risk.
14 citations
,
October 2018 in “Journal of Mind and Medical Sciences” Early screening and a mix of treatments help manage postpartum depression.
11 citations
,
January 2016 in “The Journal of Sexual Medicine” Young women with nonclassic congenital adrenal hyperplasia may experience worse sexual function and mild depression compared to healthy women.
2 citations
,
August 2024 in “Frontiers in Psychology” Drinking sugary drinks may increase depression, while exercise may reduce it.
February 2026 in “Cureus” Testosterone therapy had limited benefits for a man with depression and suspected low testosterone, highlighting the need for careful diagnosis and treatment planning.