156 citations
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August 2016 in “Journal of controlled release” Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.
151 citations
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July 2011 in “Archives of Dermatological Research” Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.
9 citations
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January 2015 in “Springer eBooks” Using hair follicles can improve skin drug delivery.
10 citations
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July 2021 in “European journal of pharmaceutics and biopharmaceutics” Nanoparticles sized between 470 and 750 nm are best for delivering substances like caffeine into hair follicles for absorption.
July 2022 in “Journal of Investigative Dermatology” The new minoxidil hydrogel is a promising alternative for hair loss treatment, with similar effectiveness and less skin irritation.
9 citations
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January 2023 in “Langmuir” Solubility in skin changes with hydration, affecting chemical absorption.
8 citations
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November 2007 in “Skin Pharmacology and Physiology” Stretching skin improves retinyl ascorbate delivery.
6 citations
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January 2022 in “Database” The data set helps improve predictions of how substances are absorbed through pig skin.
2 citations
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December 2022 in “Journal of toxicologic pathology” Skin structure complexity and variability are crucial for assessing skin toxicity in safety tests.
2 citations
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December 2021 in “BMC veterinary research” Long-term use of difluprednate eye drops in dogs can lead to hair loss and hormone imbalance.
2 citations
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January 2016 in “SANGYO EISEIGAKU ZASSHI” Nurses are exposed to chemotherapy drugs, risking health issues like hair loss, so protective gear and monitoring are needed.
20 citations
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August 2007 in “Molecular therapy” Applying a DNA vaccine to skin with active hair growth boosts immune response and protection against anthrax in mice.
16 citations
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August 2004 in “Tetrahedron” Scientists made all eight versions of a compound called cyoctol, but found it's not an anti-androgen and it fully breaks down in the skin.
10 citations
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January 2000 in “Journal Of Cutaneous Laser Therapy” Laser hair removal might also work by damaging blood vessels around hair follicles.
June 2025 in “International Journal of AYUSH Case Reports” Ayurvedic treatment successfully regrew hair in a woman with alopecia areata.
4 citations
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February 2021 in “Journal of Pharmaceutical Sciences” The model can help predict how finasteride and minoxidil work when applied to the scalp.
2 citations
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January 2014 Improved methods create smaller, more effective gelatin nanoparticles for skin delivery, and new caffeine nanocrystals enhance absorption and effectiveness.
35 citations
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June 2017 in “Pharmaceutical research” Researchers developed a model that shows hair follicles increase skin absorption of caffeine by 20%.
19 citations
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March 2011 in “Cutaneous and Ocular Toxicology” Some chemicals absorbed through the skin can cause serious health problems.
November 2023 in “International Journal of Pharmaceutics” The new delivery system improves treatment for hair loss by enhancing drug absorption and effectiveness.
January 2013 in “วารสารเภสัชศาสตร์อีสาน (Isan Journal of Pharmaceutical Sciences, IJPS)” Carthamus tinctorius floret extract is a safe hair growth promoter with good skin absorption.
2 citations
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September 2016 in “Journal of Dermatological Science” Squarticles, tiny particles made from sebum-derived lipids, can effectively deliver minoxidil, a hair growth drug, directly to hair follicles and skin cells, with less skin penetration and more tolerability.
117 citations
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November 2008 in “Drug Development and Industrial Pharmacy” Microemulsions can effectively deliver drugs through the skin but require careful ingredient selection to avoid irritation.
February 2024 in “International Journal For Multidisciplinary Research” Nanostructured lipid carriers are effective for treating hyperpigmentation in women aged 30-40.
101 citations
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October 2016 in “Nanomedicine: Nanotechnology, Biology and Medicine” Fullerenes show potential in skin care but need more safety research.
198 citations
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September 2007 in “Clinics in Dermatology” Radiofrequency devices effectively tighten skin without surgery.
39 citations
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December 2011 in “PLoS ONE” Radiofrequency exposure can stimulate hair growth by increasing IGF-1 in hair follicle cells.
9 citations
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April 2019 in “Dermatologic Therapy” The 1,064-nm Nd:YAG laser is versatile and effective for treating leg veins, hair removal, and skin rejuvenation, especially in darker skin types.
5 citations
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July 2003 in “Drug Development Research” Fluridil promotes hair growth safely and effectively for androgenetic alopecia.
5 citations
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January 1964 in “Naunyn-Schmiedeberg s Archives of Pharmacology” Iodine is absorbed by hair just below the skin surface.