55 citations
,
April 2017 in “Experimental Dermatology” The document describes a way to isolate and grow human hair follicle cells in 3D to help study hair growth.
87 citations
,
April 2018 in “Biochemical and Biophysical Research Communications” Exosomes from dermal papilla cells can help grow hair and might treat hair loss.
25 citations
,
April 2008 in “Archives of Dermatological Research” Encapsulated human hair cells can substitute for natural hair cells to grow hair.
16 citations
,
August 2019 in “Cell Proliferation” Keratinocytes help keep hair follicle cells and skin cells separate in 3D cultures, which is important for hair growth research.
10 citations
,
April 2013 in “Journal of Investigative Dermatology” Scientists created a model using sheep cells to study hair root formation, which can test how different substances affect hair growth.
51 citations
,
August 2013 in “Journal of Investigative Dermatology” Human skin cells can create new hair follicles when transplanted into mice.
46 citations
,
January 2020 in “Theranostics” Injecting a special gel with human protein particles can help hair grow.
41 citations
,
March 1998 in “Archives of Dermatological Research” The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.
29 citations
,
March 2010 in “Journal of Dermatological Science” Wnt3a activates certain genes in hair follicle cells, including a newly discovered one, EP2, which may affect hair growth.
23 citations
,
February 2015 in “International Journal of Molecular Sciences” Colchicine can inhibit hair growth by affecting cell activity and protein expression in hair follicles.
21 citations
,
October 2017 in “Journal of Investigative Dermatology” The document concludes that understanding dermal papilla cells is key to improving hair regeneration treatments.
8 citations
,
November 2020 in “Frontiers in Cell and Developmental Biology” Certain genes are more active in baby scalp cells and can help grow hair when added to adult mouse skin cells.
April 2021 in “Journal of Investigative Dermatology” The research found genes that may protect certain scalp cells from hair loss.
17 citations
,
December 2001 in “Journal of Investigative Dermatology” The osteopontin gene is active in a specific part of rat hair follicles during a certain hair growth phase and might affect hair cycle and diseases.
14 citations
,
October 2000 in “Genomics” Rat dermal papilla cells have unique genes crucial for hair growth.
6 citations
,
November 2020 in “Molecular and Cellular Endocrinology” Androgens reduce BMP2, which weakens the ability of certain cells to help hair stem cells become different types of cells.
18 citations
,
February 2018 in “International Journal of Molecular Sciences” PGD2 increases androgen receptor activity in hair cells, which could be targeted to treat hair loss.
1 citations
,
March 2019 in “KnE life sciences” HDPCM treatment healed a baby's congenital skin defect caused by varicella infection.
16 citations
,
January 2016 in “Annals of Dermatology” Green tea component EGCG may help prevent hair loss by changing microRNA levels in certain scalp cells.
3 citations
,
January 2018 in “Biomedical dermatology” Green tea extract helps prevent cell death and supports cell survival in hair cells exposed to a chemotherapy drug.
December 2022 in “Cureus” Hormones significantly influence hair growth, with conditions like hirsutism and patterned hair loss linked to hormone levels; more research is needed for full understanding.
June 2025 in “Universal library of medical and health sciences.” External factors like pollution, stress, and poor nutrition can negatively affect hair growth.
Recombinant type XVII collagen may help regrow hair by activating specific cell pathways.
5 citations
,
April 2022 in “Frontiers in Medicine” Hair and skin healing involve complex cell interactions controlled by specific molecules and pathways, and hair follicle cells can help repair skin wounds.
September 2022 in “Frontiers in Bioengineering and Biotechnology” Taxifolin from Rhododendron mucronulatum may help prevent hair loss and promote hair growth.
4 citations
,
May 2012 in “Tissue Engineering and Regenerative Medicine” Scientists created three types of structures to help regrow hair follicles, and all showed promising results for hair regeneration.
September 2025 in “PubMed” Mechanical stimulation and new therapies show promise for hair regrowth.
January 2014 in “Journal of Investigative Dermatology” Proteins like aPKC and PDGF-AA, substances like adenosine and ATP, and adipose-derived stem cells all play important roles in hair growth and health, and could potentially be used to treat hair loss and skin conditions.
2 citations
,
January 2023 in “International Journal of Biological Sciences” A specific pathway involving AR, miR-221, and IGF-1 plays a key role in causing common hair loss.
88 citations
,
December 2018 in “Advanced Healthcare Materials” Layer-by-Layer self-assembly is promising for biomedical uses like tissue engineering and cell therapy, but challenges remain in material safety and process optimization.