research Commentary on: Hairless and the polyamine putrescine form a negative regulatory loop in the epidermis
The commentary explains that a balance of HR protein and putrescine is important for normal hair growth.
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90-120 / 1000+ results research Differential dependency of unmyelinated and A delta epidermal and upper dermal innervation on neurotrophins, trk receptors, and p75LNGFR.
Neurotrophins regulate nerve growth by balancing promotion and suppression.
research Expression of laminin, type IV collagen and fibronectin molecules is related to embryonal skin and epidermal appendage morphogenesis.
Laminin, type IV collagen, and fibronectin help develop skin and hair structures in embryos.
research 167 Epidermal GRK2 knockout triggers a hair loss phenotype with features resembling immune-mediated alopecias
Removing GRK2 in skin cells causes hair loss similar to immune-related alopecia.
research Resident Stem Cell in Skin
Skin stem cells can help improve skin repair and regeneration.
research Hair Follicle Regeneration Using Grafted Rodent and Human Cells
Grafted rodent and human cells can regenerate hair follicles, but efficiency decreases with age.
research Mesenchymal Stem Cells From Mouse Hair Follicles Reduce Hypertrophic Scarring in a Murine Wound Healing Model
Mouse stem cells from hair follicles can improve wound healing and reduce scarring.
research Skin Biology: Understanding Biological Targets for Improving Appearance
The document concludes that a deeper understanding of skin aging and photodamage is needed to create better skin treatments.
research In vitro induction of hair follicle signatures using human dermal papilla cells encapsulated in fibrin microgels
Human cells in plasma-derived gels can potentially mimic hair follicle environments, improving hair regeneration therapies.
research Dermo‐epidermal interactions in reptilian scales: Speculations on the evolution of scales, feathers, and hairs
Reptilian scales, feathers, and hairs evolved from changes in skin cell interactions.
research Expression of COUP-TF-interacting protein 2 (CTIP2) in mouse skin during development and in adulthood
CTIP2 may help in skin development and maintenance.
research Decision letter: Hair follicle epidermal stem cells define a niche for tactile sensation
Hair follicle stem cells are crucial for touch sensation and proper nerve structure in mice.
research Direct conversion of mouse and human fibroblasts to functional melanocytes by defined factors
Fibroblasts can be turned into melanocytes for potential skin treatments.
research Advanced therapies of skin injuries
New skin substitutes for treating severe burns and chronic wounds are being developed, but a permanent solution for deep wounds is not yet available commercially.
research Skin Cell Heterogeneity in Development, Wound Healing, and Cancer
Different types of skin cells play specific roles in development, healing, and cancer.
research Transcriptome Sequencing Reveals Differences between Primary and Secondary Hair Follicle-derived Dermal Papilla Cells of the Cashmere Goat (Capra hircus)
Primary and secondary hair follicle cells in Cashmere goats have different gene expressions affecting hair growth and size.
research Reflectance confocal microscopy for scarring and non-scarring alopecia real-time assessment
Reflectance confocal microscopy can help tell apart scarring from non-scarring hair loss.
research Sequential Scalp Assessment in Hair Regeneration Therapy Using an Adipose-Derived Stem Cell–Conditioned Medium
Using a special stem cell formula on the scalp once a month for six months helped people with hair loss grow more hair.
research Dermal fibroblasts: the terminology, heterogeneity of subpopulations and common properties
Dermal fibroblasts have at least three distinct types, each with unique roles in skin structure and hair development.
research Transdifferentiation of corneal epithelium: evidence for a linkage between the segregation of epidermal stem cells and the induction of hair follicles during embryogenesis.
Corneal cells can transform into hair-producing skin cells when exposed to certain signals.
research Functionally distinct melanocyte populations revealed by reconstitution of hair follicles in mice
Only skin melanocytes, not other types, can color hair in mice.
research SOX2 in the Skin
SOX2 is crucial for skin cell function and hair growth, and it plays a role in skin cancer and wound healing.
research Human skin stem cells and the ageing process
Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.
research Regenerating the skin: a task for the heterogeneous stem cell pool and surrounding niche
Different types of stem cells and their environments are key to skin repair and maintenance.
research Topical Delivery of Protein and Peptide Using Novel Cell Penetrating Peptide IMT-P8
The peptide IMT-P8 can effectively deliver proteins into the skin and cells for potential skin treatments.
research Interfollicular epidermal stem-like cells for the recreation of the hair follicle epithelial compartment
Human skin cells with stem-like features can help create new hair follicles and sebaceous glands when combined with other cells.
research Endogenous human skin equivalent promotes in vitro morphogenesis of follicle-like structures
Endo-HSE helps grow hair-like structures from human skin cells in the lab.
research Stem cells and the skin
Stem cells can rejuvenate skin, restore hair, and aid in wound healing.
research From skin microrelief to wrinkles. An area ripe for investigation
Wrinkles form due to structural skin changes and vary in type and treatment response.
research Template for Skin Regeneration
The dermal regeneration template is effective in skin regeneration, reducing scarring, and has potential for future improvements.