65 citations
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April 2018 in “Oncotarget” Anabolic androgenic steroids can increase cancer risk and disrupt hormones.
53 citations
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October 1984 in “Endocrine reviews” Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.
49 citations
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November 1992 in “Archives of dermatology” Different treatments for alopecia areata have varying success rates and side effects; intralesional steroids are most effective.
46 citations
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August 2019 in “Journal of Ethnopharmacology” Eclipta prostrata has many traditional uses and health benefits, but more research is needed to understand how it works and ensure it's safe.
37 citations
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September 2018 in “Psychoneuroendocrinology” Finasteride treatment in male rats causes long-lasting effects on depression-like behavior, brain cell growth, inflammation, and gut bacteria composition.
31 citations
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October 2012 in “Archives of ophthalmology” Laser hair reduction near the eyebrows can cause serious eye injuries even with safety measures.
29 citations
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August 2008 in “Current Opinion in Pediatrics” Hair loss in teenagers is hard to treat and lacks a cure, with some treatments available depending on the type of hair loss.
27 citations
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October 2016 in “The Journal of Clinical Endocrinology and Metabolism” Daughters of women with PCOS generally experience normal puberty but may have more body hair and different body fat distribution.
25 citations
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July 2019 in “Experimental Dermatology” Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.
23 citations
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January 2010 in “Journal of The American Academy of Dermatology” Effective treatments for lichen planopilaris are unclear due to inconsistent results and a lack of strong research evidence.
20 citations
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February 2002 in “Expert Opinion on Therapeutic Patents” New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.
19 citations
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March 1998 in “Endocrinology” Male rats have more somatostatin neurons than females due to testosterone converting to estrogen during early development.
16 citations
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September 2016 in “Neuropharmacology” Activating TSPO helps protect the retina from damage caused by high eye pressure in glaucoma.
15 citations
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February 2019 in “Internal Medicine Journal” Australian doctors experienced in adult transgender healthcare mostly prescribe intramuscular testosterone and oral estradiol, recommend mental health assessments before hormone therapy, and support improved training and guidelines.
14 citations
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April 2019 in “International Journal of Women's Health” Some treatments can stabilize Frontal Fibrosing Alopecia, but more research is needed to find effective treatments, and hair transplants often fail.
14 citations
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September 2015 in “Expert Opinion on Therapeutic Targets” The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.
14 citations
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November 2006 in “Current Medicinal Chemistry” New treatments for enlarged prostate are being developed to be more effective and have fewer side effects.
13 citations
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January 2015 in “Steroids” The study created a model to help design new inhibitors for steroidal 5α-reductase enzymes.
11 citations
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November 2021 in “International journal of molecular sciences” Gut microbes significantly affect brain steroid levels.
11 citations
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October 2020 in “General and comparative endocrinology” Male C57BL/6 mice show age-related fluctuations in certain hormones and their ratios in both blood and hair.
11 citations
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August 2020 in “Diabetes” Testosterone helps human pancreatic cells increase insulin release.
8 citations
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May 1982 in “Journal of Endocrinology/Journal of endocrinology” Rat skin takes up and processes testosterone differently than other organs, with testosterone being more important for the skin than its metabolite 5α-DHT.
7 citations
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June 2019 in “Australasian Journal of Dermatology” Elderly men with a scalp condition healed in about 26 days using specific creams and dressings, with no return of the condition in 6 months.
6 citations
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October 1993 in “Endocrinology” Finasteride blocks progesterone production in specific tumor cells, potentially causing side effects.
5 citations
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March 2014 in “Journal of The American Academy of Dermatology” The study suggests hormonal factors may play a role in Frontal Fibrosing Alopecia and that treatments like oral antiandrogens and steroids could be beneficial.
4 citations
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January 1987 in “Annual reports in medicinal chemistry” New treatments for skin diseases are more effective and patient-friendly, but many still lack a cure.
2 citations
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May 2024 in “European Journal of Investigation in Health Psychology and Education” Many bodybuilders in Sergipe, Brazil use anabolic steroids, facing health risks like acne, irritability, and hypertension.
2 citations
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November 2017 in “Elsevier eBooks” Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.
2 citations
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October 2016 Chemotherapy and radiotherapy can cause skin side effects like rashes, hair loss, and nail changes, which are usually managed with conservative treatments.
1 citations
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January 2024 in “NPJ breast cancer” Experts agree on how to manage sugar levels and skin reactions in patients taking the cancer drug alpelisib.