October 2023 in “Journal of the American Academy of Dermatology” Clascoterone cream could be used for other skin conditions affected by hormones.
3 citations
,
July 2009 in “Experimental and Clinical Endocrinology & Diabetes” Low-dose Buserelin effectively reduces hirsutism with minimal side effects.
36 citations
,
May 2011 in “The Journal of Clinical Endocrinology & Metabolism” Treatment with a hormone agonist can reduce excess male hormones in postmenopausal women without surgery.
March 2024 in “BMC women's health” The levonorgestrel implant increases free testosterone and lowers SHBG more than DMPA-IM and the copper IUD.
44 citations
,
June 1985 in “Fertility and sterility” Combination drug therapy is effective for hirsutism that doesn't improve with just one medication.
19 citations
,
March 1994 in “Fertility and sterility” The combination therapy reduced hirsutism in women with PCOD and was well-tolerated.
31 citations
,
January 2008 in “Gynecological endocrinology” Both birth control pills improved hormone levels and skin conditions in women with hyperandrogenism, but the one with drospirenone was more effective.
Spironolactone with an oral contraceptive improved hair growth in women with hirsutism.
December 2025 in “Fertility and Sterility” Both LNG-IUD and systemic progestins are effective for fertility-sparing treatment, but close monitoring is needed due to recurrence risk.
November 2014 in “DOAJ (DOAJ: Directory of Open Access Journals)” Nanostructured lipid carriers can effectively deliver spironolactone to hair follicles for treating hair loss.
October 2022 in “Journal of the ASEAN Federation of Endocrine Societies” GnRH-a or orchiectomy is more effective than anti-androgens for managing hormone levels in transgender women.
77 citations
,
October 1986 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Nafarelin may effectively treat excessive hair growth in women by reducing certain hormone levels.
101 citations
,
January 1985 in “British Journal of Dermatology” Spironolactone is effective for treating acne, hirsutism, and androgenic alopecia in women with few side effects.
January 2024 in “International Journal of Health Science” Hormonal implants have many side effects that often outweigh their benefits.
4 citations
,
January 1991 in “Journal of dermatological treatment” Goserelin and oestradiol treatment slightly improved hairiness but did not significantly change sebum production or hair characteristics in mildly hirsute women.
21 citations
,
December 2012 in “Maturitas” Testosterone implants in women require pharmacological dosing to be effective and are generally safe and well-tolerated.
4 citations
,
July 2022 in “Clinical Cosmetic and Investigational Dermatology” Clascoterone 1% cream is a promising new treatment for acne.
14 citations
,
March 2020 in “Journal of Medical Internet Research” PrEP implants are promising for HIV prevention if the number of implants needed is minimized.
27 citations
,
October 2020 in “Drugs” Clascoterone cream was approved in the USA for treating acne in people aged 12 and older.
5 citations
,
July 1987 in “European Journal of Obstetrics & Gynecology and Reproductive Biology” The treatment temporarily improved symptoms of hyperandrogenism in adolescents.
January 1989 in “Oxford University Research Archive (ORA) (University of Oxford)” Spironolactone effectively reduces unwanted hair growth in women with hirsutism.
October 2025 in “Journal of the Endocrine Society” Goserelin injections can effectively manage hyperandrogenism symptoms in postmenopausal women who can't have surgery.
9 citations
,
June 2020 in “Actas Dermo-Sifiliográficas” Spironolactone is effective for acne, hidradenitis suppurativa, female hair loss, and hirsutism but is underused in dermatology.
8 citations
,
August 2020 in “Clinical and Experimental Dermatology” Spironolactone is a low-cost, effective, and generally safe treatment for various skin conditions related to hormones.
1 citations
,
June 2024 in “Revista Colombiana de Endocrinología Diabetes & Metabolismo” The risks of testosterone implants in women outweigh the benefits.
37 citations
,
May 2018 in “Transgender health” Oral estradiol works for many transgender women but needs personalized dosing and monitoring.
1 citations
,
December 2025 in “Baylor University Medical Center Proceedings” Leuprolide may better manage cholesterol and blood pressure in PCOS than spironolactone.
9 citations
,
April 2021 in “Expert opinion on pharmacotherapy” Clascoterone is a new, effective, and safe acne treatment without systemic side effects.
34 citations
,
October 2014 in “European journal of pharmaceutics and biopharmaceutics” The new drug delivery system releases the drug better in sebum and targets follicles more effectively than the conventional cream.
Ovulation inhibitors effectively treat menstrual issues and improve fertility but can have side effects.