research FDA declines approval of testosterone drug for third time
The FDA rejected a testosterone drug again due to safety concerns.
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research [Acceptability, tolerance and quality of life impact of cyproterone acetate treatment in female hirsutism. Comparison of 2 protocols in combination with oral or transdermal estradiol].
Cyproterone acetate with estradiol improved women's self-confidence and emotional well-being without a difference between oral or transdermal methods, but younger women preferred the oral method.
research Effect of norplant on androgens and sexual function
Norplant implants lower some androgen levels but don't significantly change sexual function.
research Effects of 17 α-ethinylestradiol,Norethindrone and Levonorgestrel on Root Growth of Arabidopsis thaliana
Norethindrone and levonorgestrel can enhance or inhibit root growth in Arabidopsis thaliana depending on the concentration.
research Novel Synthetic Steroid Derivatives: Target Prediction and Biological Evaluation of Antiandrogenic Activity
New steroid compounds may help with hormonal therapy and have potential benefits for glucose disorders, but more research is needed.
research Androgen Therapy for Postmenopausal Women; What is New?
research Regression of Pathologic Changes Induced by the Long-term Administration of Contraceptive Steroids to Rodents
Some steroid-induced health issues in rodents improved after stopping treatment, but hair loss and eye problems did not.
research SUN-144 Initiating Estradiol Hormone Therapy in a Transgender Woman With Multifocal Idiopathic Localization-Related Epilepsy
The patient was satisfied with hormone therapy, and her epilepsy remained stable.
research Changes in expression of the δ subunit of the GABAAreceptor and in receptor function induced by progesterone exposure and withdrawal
Progesterone affects GABAA receptor function by altering δ subunit levels.
research Spironolactone use and oocyte maturation in patients undergoing controlled ovarian hyperstimulation
research Achieving Physiologic 17-ẞ-Estradiol Levels in Transgender Females on Estradiol Transdermal Patches and Optimal Dosing
Transgender females can reach their target estrogen levels using estradiol patches, especially if oral treatments fail or if they're at risk for blood clots. Often, the highest dose patch is needed.
research New Aromatic Esters of Progesterone as Antiandrogens
New progesterone-based compounds can block male hormones.
research Local stimulation of sebaceous gland activity by the topical administration of dehydroepiandrosterone
Topical DHEA safely increases skin oil production.
research A Review of Gender-Affirming Hormone Therapy for Transgender and Gender Diverse Adults in South Korea
Gender-affirming hormone therapy in South Korea aligns with international guidelines and has specific side effects.
research Semaglutide Treatment of Excessive Body Weight in Obese PCOS Patients Unresponsive to Lifestyle Programs
Semaglutide helps obese PCOS patients lose weight and improve health.
research Virilizing Ovarian Tumor in a Postmenopausal Women
research A randomized placebo-controlled study on the effects of pioglitazone on cortisol metabolism in polycystic ovary syndrome
Pioglitazone improved insulin sensitivity and altered cortisol metabolism in PCOS patients.
research Effective treatment of skin and metabolic manifestations of hyperandrogenism: a comprehensive improvement of quality of life
Combined oral contraceptives improve skin, hormone levels, and quality of life in women with PCOS.
research The anticonvulsant effects of progesterone and its metabolites
5alpha-DHP may be a safe, effective treatment for certain seizures without causing sedation.
research Correlations between hormonal intrauterine devices and androgenic skin conditions: A retrospective cohort study
Hormonal intrauterine devices (IUDs) may cause or worsen skin conditions influenced by androgens.
research NDA Submission of Vepdegestrant (ARV-471) to U.S. FDA: The Beginning of a New Era of PROTAC Degraders
Vepdegestrant may become the first FDA-approved PROTAC degrader, marking a new era in drug development.
research Latanoprost
research Utilization of Contraception Methods and Side Effects among Women Attending the Maternal and Child Healthcare Centers in Mukalla City, Hadhramout, Yemen
Many women using contraception in Mukalla, Yemen, experience side effects like hair loss and mood swings, needing personalized care.
research Latest advances in oral hormonal male contraception: efficacy, mechanisms of action, and future perspectives
New male contraceptive pills show promise in reducing sperm production with mild side effects.
research Chronic progesterone treatment augments while dehydroepiandrosterone sulphate prevents tolerance to ethanol anxiolysis and withdrawal anxiety in rats
Progesterone increases alcohol tolerance and withdrawal anxiety, while DHEAS prevents them.
research The curative effect of metformin in combination with dyne-35 on the treatment of polycystic ovary syndrome and on the ovulation rate and pregnancy rate
Metformin combined with dyne-35 increases ovulation and pregnancy rates in PCOS patients.
research Evaluation of an eucalyptus oil containing topical drug delivery system for selected steroid hormones
The eucalyptus oil system improved skin delivery of hormones, but safety concerns remain.
research FINASTERIDE (PLUS ORAL CONTRACEPTIVE PILL) VS METFORMIN IN TREATMENT OF POLYCYSTIC OVARY SYNDROME-RELATED INFERTILITY: A PROSPECTIVE RANDOMIZED TRIAL
research Novel progestogenic androgens for male contraception: design, synthesis, and activity of C7 α-substituted testosterone
New testosterone analogs show promise for male contraception with better activity and potentially fewer side effects.
research 11α-Hydroxyprogesterone, a potent 11β-hydroxysteroid dehydrogenase inhibitor, is metabolised by steroid-5α-reductase and cytochrome P450 17α-hydroxylase/17,20-lyase to produce C11α-derivatives of 21-deoxycortisol and 11-hydroxyandrostenedione in vitro
11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.