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PAD3 plays a key role in hair and skin protein structure and may be linked to skin diseases.

Enzymes that change arginine to citrulline are important for skin barrier and hair formation, and their malfunction can lead to skin conditions and hair disorders.

Near-infrared probes can safely and effectively image cysteine protease activity for disease diagnosis.

Human hair keratin scaffold material degrades in muscles mainly through the ubiquitin system with lysosome help.

The protein FLCN is involved in cellular cleanup and is regulated by ULK1.

Cystatin M/E strongly inhibits cathepsin V and cathepsin L, important for skin formation.

Researchers fixed gene mutations causing a skin disease in stem cells, which then improved skin grafts in mice.

Scientists created a cell model to study and find treatments for a skin disease called RDEB.

A peptide known for reducing wrinkles also effectively inhibits an enzyme linked to skin inflammation and acne.

PROTAC technology shows promise for cancer treatment but needs more effective E3 ligase recruiters.

The enzyme Rand protease works well for leather dehairing and its stability is important, with Leu75 playing a key role.

SETDB1 is essential for controlling DNA methylation, silencing retrotransposons, and maintaining skin cell health, with its absence leading to skin inflammation and hair loss.

Accurate diagnosis of RDEB-mitis in older adults is crucial for proper management without immunosuppressants.

Scientists created cell lines to study a genetic skin disorder using CRISPR technology.

Bikunin is found on the cell boundaries of certain skin layers and may help regulate skin and hair functions.

Scientists developed a new way to study mutations in a skin condition using blood cells, which may help diagnose and treat the disease.

Astrotactin-2 is cleaved in a specific way that helps understand its maturation.

Hair plucking quickly increases antizyme, reducing a specific enzyme activity in rats.

PADs are crucial for healthy skin and hair, and their imbalance can cause skin and hair disorders.

Sebum helps protect human skin from microbes.

Daprodustat, combined with PAβN, could be a new antibacterial treatment.

PAD enzymes play a key role in hair growth and structure.

Dock5 is important for skin healing and could help treat diabetic wounds.

PROTACs offer a new, precise way to treat cancer by breaking down harmful proteins.

The research showed that CRISPR/Cas9 can fix mutations causing a skin disease in stem cells, which then improved skin grafts in mice, but more work on safety and efficiency is needed.

PROTACs offer new ways to treat hard-to-target diseases, with promising drugs for cancer in advanced trials.

PLAU and SerpinB2 affect cell death differently in various forms of leprosy and could be targets for new treatments.