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The NUDT15 R139C variant causes thiopurine-induced leukocytopenia through a different mechanism than previously thought in Japanese patients with inflammatory bowel disease.

Accurate protein modeling can help develop new treatments for prostate cancer and other diseases.

18-MEA and cationic surfactants can restore and maintain hair's hydrophobic nature, improving its beauty and feel.

The study concluded that a protein important for hair strength is regulated by certain molecular processes and is affected by growth phases.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

Mutations in the DSG4 gene cause fragile, sparse hair in humans, mice, and rats.

Understanding how EDC genes are regulated can help develop better drugs for skin diseases.

Deuruxolitinib significantly improves hair satisfaction in severe alopecia areata patients.

Two peptides, RMYYY and VMYMI, may be effective anti-inflammatory drugs.

The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.

The mutant HR bmh protein mis-localizes in cells, affecting skin and hair development.

Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.

Malt1 protease is essential for regulatory T cell function and could be targeted to boost antitumor immunity.

Staphylococcus aureus delays wound healing by disrupting lipid metabolism in skin cells.

Familial dyskeratotic comedones are a rare, inherited skin condition that is hard to treat but may improve slightly with topical retinoids and urea cream.

Specialized ribosomes affect aging in human skin cells.

PSENEN gene mutations can cause both Dowling-Degos disease and acne inversa.

Some treatments can improve skin's defense against damage, but overuse may cause other skin problems.

Stilbamidine and hydroxystilbamidine inhibit enzyme release from lysosomes and have effects similar to cortisol and chloroquine.

Middle Eastern patients with epidermolysis bullosa show specific genetic mutations linked to different types of the disease.

Nanozymes greatly improve biocatalysis by being stable, efficient, and versatile.

Human hair contains diverse proteins, including keratins and histones, which could help assess hair health and aging.

CYP154C7 enzyme can effectively modify steroids and is promising for commercial use.

LSD1 and HSP90 help heal skin wounds by changing hair follicle stem cells' metabolism.

Trichothiodystrophy involves brittle hair due to low sulfur amino acids, not a transport defect.

Type II keratins are uniquely phosphorylated during stress and mitosis, affecting their structure and function.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

Mutants of CYP154C2 enzyme significantly improved steroid conversion efficiency.