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A new compound slows cancer cell growth and causes cell death by blocking cell cycle progression and increasing cell-damaging molecules.

A new EDA gene mutation was found in a Chinese family with a specific skin disorder.

The document concludes that the technique allows for the detection of LDH activity in various tissues, showing where cells are actively metabolizing glucose.

Agouti and AGRP affect pigmentation and obesity, with implications for metabolic disorders.

Researchers found a gene in hamsters that responds to male hormones and may be indirectly controlled by them.

New pyridine compounds effectively inhibit GSK3, a diabetes treatment target.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

TCDD speeds up skin barrier formation by increasing certain gene expressions.

Dapagliflozin helps protect heart cells under stress by improving mitochondrial function and reducing cell damage.

Extracellular ATP is crucial for plant root growth and signaling.

BMP-2 activates the Dlx3 gene in mouse skin cells, important for hair and skin development.

Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.

Increasing COX-2 in mouse skin causes bigger sebaceous glands and thinner hair, but stopping COX-2 can reverse hair thinning.

New treatments targeting androgen receptors show promise for drug-resistant prostate cancer.

The EDAR V370A allele in East Asians likely evolved due to reliance on aquatic resources providing essential nutrients.

The EDAR V370A allele in East Asians likely evolved due to reliance on aquatic resources providing essential nutrients.

A new method helps detect androgen receptor movement in cells, aiding research on hair loss treatments.

GT20029 helps regrow hair in men with hair loss and is well-tolerated.

Human liver enzyme DHEA ST helps process minoxidil.

A gene mutation worsens skin irritation in mice due to a lack of certain fats.

Loss of Dnmt3a and Dnmt3b increases aggressive skin tumors by affecting PPAR-γ.

PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.

KRTAP2 genes are crucial for hair structure and may impact hair disorders and treatments.

A specific ATR gene mutation is linked to a hereditary oropharyngeal cancer syndrome.

Dihydrotestosterone changes some hormone-related gene expressions in rat pituitary glands but doesn't affect the estrous cycle.

Adding a second method to PROTACs could improve cancer treatment.

TPA strongly increases ODC activity in certain skin cells, potentially aiding tumor growth.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

TGF-β2 plays a key role in human hair growth and development.

Androgen self-administration might be controlled by membrane receptors, not nuclear ones.