30 citations
,
April 2007 in “Dermatologic Clinics” The document concludes that new treatments are needed to better manage acne and reduce side effects related to current therapies.
30 citations
,
April 1997 in “European journal of endocrinology” The document concludes that managing hirsutism involves identifying the cause, using a scoring system for severity, combining cosmetic and medical treatments, encouraging weight loss, and providing psychological support, while noting the need for more research on drug treatments.
29 citations
,
July 2012 in “The Journal of Sexual Medicine” Rats had lasting erectile problems after stopping a certain medication.
24 citations
,
January 2001 in “Dermatologic clinics” Hormonal therapy is a treatment option for acne, the only medical treatment for hirsutism, and the most promising for androgenetic alopecia.
21 citations
,
July 2014 in “Clinics in Dermatology” Hormonal contraceptives can help treat acne by affecting sebum production and androgen levels.
20 citations
,
April 2006 in “Dermatologic Clinics” Antiandrogen therapies are beneficial for treating skin and hair conditions related to androgen levels.
19 citations
,
January 1997 in “Dermatologic Clinics” Most treatments for hair loss in 1997 were not effective for most people, and maintaining hair growth was difficult.
17 citations
,
May 2003 in “Journal of The American Academy of Dermatology” Hair from balding and non-balding areas regrows similarly on mice.
14 citations
,
November 2008 in “Expert opinion on drug metabolism & toxicology” Finasteride helps treat prostate issues and may prevent prostate cancer in high-risk men.
11 citations
,
January 1998 in “Dermatology” Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.
8 citations
,
October 1988 in “Clinics in Dermatology” Current research explores hair growth drugs, while future research aims for personalized treatments.
7 citations
,
January 2019 in “The Aging Male” Post-finasteride syndrome's existence is uncertain; more research needed.
7 citations
,
February 2016 in “Arab journal of urology” People with early hair loss may have a higher chance of enlarged prostate and metabolic syndrome, so they should be checked for urinary and metabolic issues.
6 citations
,
July 2013 in “Acta Clinica Belgica” The document concludes that combination therapy is most effective for treating excessive hair growth in women with idiopathic hirsutism, and more research is needed to understand the condition.
5 citations
,
January 2021 in “Journal of Cosmetic Dermatology” Topical cetirizine 1% promotes hair growth in male androgenetic alopecia patients.
5 citations
,
October 2010 in “General and Comparative Endocrinology” Flutamide and finasteride reduced sex hormones in pregnant hyenas, but increased them in males.
3 citations
,
January 1994 in “Toxicological Sciences” Finasteride causes abnormal growth in male mice cells at high doses.
2 citations
,
March 2018 in “Current Opinion in Urology” 5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.
2 citations
,
January 2014 in “Springer eBooks” Polycystic Ovary Syndrome (PCOS) often leads to severe acne, and lifestyle changes and hormonal treatments can help manage it.
2 citations
,
January 2012 in “Journal of metabolic syndrome” The document concludes that hirsutism can be managed with various treatments tailored to the individual, potentially improving quality of life.
January 2016 in “Archivio italiano di urologia, andrologia” The document concludes that the risk of sexual side effects from 5-alpha-reductase inhibitors is low and often temporary, but more research is needed on potential permanent effects.
January 2016 in “Springer eBooks” The document concludes that there are various causes and treatments for hair loss, with hair transplantation being a notable option.
January 2007 in “El Servicio de Difusión de la Creación Intelectual (National University of La Plata)” Combining D-004 and finasteride is more effective at reducing prostate enlargement than using either alone.
December 2022 in “Scholars journal of applied medical sciences” Dutasteride 0.5mg improves hair growth in 78% of people with hair loss, but may cause sexual problems in some.
196 citations
,
May 2001 in “The journal of investigative dermatology/Journal of investigative dermatology” Sebocytes play a key role in controlling androgen levels in human skin.
139 citations
,
June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Androgenetic alopecia in women needs more research and better management strategies.
100 citations
,
April 2010 in “Expert Opinion on Pharmacotherapy” Hair loss in men treated best with early medication or transplant, new treatments researched.
100 citations
,
September 1999 in “British Journal of Dermatology” The study found that two enzymes linked to hair loss are located in different parts of the scalp, supporting a common treatment's effectiveness.
99 citations
,
October 2006 in “BMC clinical pharmacology” Finasteride may cause slight depression and anxiety.
86 citations
,
March 1993 in “Toxicology and Applied Pharmacology” Finasteride affects male rat genitalia development, causing abnormalities during specific pregnancy days.