168 citations
,
January 2005 in “Journal of Investigative Dermatology” Male and female mice have different skin thickness, and hormones affect their skin and hair growth differently.
165 citations
,
December 2002 in “Molecular and Cellular Endocrinology” Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.
155 citations
,
October 2002 in “The FASEB Journal” Heart-specific steroid metabolism is crucial in cardiac hypertrophy.
153 citations
,
April 2009 in “Urology” Prostate cancer was a major health issue in 2009, especially for Black men, and targeting the 5alpha-reductase enzyme could help in its prevention and treatment.
149 citations
,
January 2011 in “Nature reviews. Urology” Hormonal interactions, especially involving DHT and estrogen, play a key role in BPH development and treatment.
147 citations
,
October 2004 in “Experimental dermatology” Hormones like testosterone affect skin functions and can cause skin issues when in excess; treatments to manage these effects are only somewhat effective.
147 citations
,
April 1990 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride safely lowers DHT levels without affecting testosterone.
146 citations
,
January 2004 in “Hormones” Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.
142 citations
,
February 1985 in “Fertility and sterility” Spironolactone reduced hair thickness and some testosterone levels in women with excessive hair growth.
140 citations
,
January 2021 in “Journal of the International Society of Sports Nutrition” Creatine is safe, not a steroid, and boosts muscle and performance without causing kidney damage or hair loss.