research The acne hormones
Eating high-glycemic and dairy foods can increase hormones that may cause acne and other health issues.
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research Formononetin: Novel Deal for Androgenetic Alopecia
Formononetin, found in red clover, may treat hair loss with fewer side effects.
research Current and Future Medical Treatment of Androgenetic Alopecia
Treatments for hair loss vary, but cell-based options may be the future.
research Spermatozoa and Chronic Treatment with Finasteride: A TEM and FISH Study
Finasteride may negatively affect male fertility.
research Sebocytes are the Key Regulators of Androgen Homeostasis in Human Skin
Sebocytes play a key role in controlling androgen levels in human skin.
research Finasteride-associated male infertility
Finasteride may worsen infertility in men with existing issues, but stopping it can improve sperm health.
research Negative Impact of Testosterone Deficiency and 5α-Reductase Inhibitors Therapy on Metabolic and Sexual Function in Men
Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.
research Steroidogenic Isoenzymes in Human Hair and Their Potential Role in Androgenetic Alopecia
Steroidogenic isoenzymes may help improve treatments for common hair loss.
research Structure of human steroid 5α-reductase 2 with the anti-androgen drug finasteride
Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.
research Finasteride-induced depression: new insights into possible pathomechanisms
Finasteride may increase depression by reducing brain cell growth.
research 5α-Reductase isozymes and aromatase mRNA levels in plucked hair from young women with female pattern hair loss
Higher enzyme levels found in women with hair loss, suggesting hormone imbalance.
research Therapeutic Androgen Receptor Ligands
Androgens and SARMs play a role in body mass, frailty, skin health, and hair growth, and are used in treating prostate cancer, acne, and hair loss, with potential for new uses and improved versions in the future.
research A Systemic Review on Topical Marketed Formulations, Natural Products, and Oral Supplements to Prevent Androgenic Alopecia: A Review
Various treatments, including FDA-approved drugs, natural products, and oral supplements, can help with hair loss, but a patient's medical history and potential allergies should be considered when choosing a treatment.
research The direct inhibitory effect of dutasteride or finasteride on androgen receptor activity is cell line specific
Dutasteride and finasteride affect different cell types differently.
research The natural history of androgenetic alopecia
AGA affects many, progresses differently, and early treatment is crucial.
research Metabolic dysfunction in female mice with disruption of 5α-reductase 1
Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.
research Development and Validation of Spectrophotometric Method for Determination of Finasteride in Pharmaceutical Formulation Using 1,2-Naphthoquine-4-sulfonate (NQS)
New method accurately measures finasteride in medicine using NQS.
research Synthesis of N-Substituted 3-Oxo-17b- carboxamide-4-aza-5a-androstanes and the Tautomerism of 3-Oxo-4-aza-5-androstenes
Researchers made two new compounds that could be used for medicine.
research Possible association between androgenic alopecia and risk of prostate cancer and testicular germ cell tumor: a systematic review and meta-analysis
Baldness, especially at the front, may lower the risk of testicular cancer by 31%, but its link to prostate cancer is unclear.
research Clomiphene citrate rescue of spermatogenesis in men with infertility while remaining on finasteride: A case report
Clomiphene citrate improves fertility in men taking finasteride for hair loss.
research Hair Restoration: Looking Beyond Minoxidil, Finasteride and Hair Transplantation
Need better hair loss treatments beyond minoxidil, finasteride, and transplants.
research Gonadal Sex Steroids: Production, Action and Interactions in Mammals
The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.
research Can beverages grow hair on bald heads?
Coffee and tea might help hair growth in balding individuals, but side effects and alternative uses are being considered.
research Determination of finasteride in human plasma by liquid chromatography–electrospray ionization tandem mass spectrometry with flow rate gradient
Researchers developed a quick and sensitive way to measure finasteride in blood using a small sample size.
research Treatment guidelines in adult women
Hormonal therapy is effective for treating acne in adult women, especially with signs of high androgen levels.
research Synthesis of phenanthridin-3-one derivatives: Non-steroidal inhibitors of steroid 5-α-reductase
New chemicals were made that can block an enzyme linked to hair loss, prostate growth, and acne.
research Blood MUC-18/MCAM expression in patients with melanoma: a suitable marker of poor outcome
High MUC-18/MCAM levels in blood indicate a worse outlook for melanoma patients.
research Preparation, Characterization and Molecular Docking Study of some New Pyrazole Derivatives Derived from 2-Mercaptobenzothiazole.
New pyrazole derivatives may help treat hair loss, but more testing is needed.
research A New Look at the 5?-Reductase Inhibitor Finasteride
Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.
research A randomized, double-blind controlled study of the efficacy and safety of topical solution of 0.25% finasteride admixed with 3% minoxidil vs. 3% minoxidil solution in the treatment of male androgenetic alopecia
Finasteride and minoxidil mix works better for hair growth than minoxidil alone, with similar safety.