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Testosterone therapy improves strength and body composition in older men with low testosterone.

The study created a new method to test drugs that affect hormone processing in skin.

Women have a higher DHT/testosterone ratio than men, possibly due to gut bacteria activity.

Testosterone's muscle-building effects do not require its conversion to DHT.

High levels of testosterone and 5α-DHT can lead to cell death in cells important for hair growth.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

Testosterone reduces knee flexibility by affecting relaxin receptors.

Lespedeza cuneata extract may help treat enlarged prostate.

Testosterone conversion to 5α-DHT may not be essential for its effects on the skin.

Thyroid hormones and androgens affect gene expression in frog reproductive organs differently between males and females.

Testosterone helps prevent skin damage in males by acting through both estrogen and androgen pathways.

Finasteride significantly reduces DHT levels in male dogs without affecting testosterone levels, suggesting it could be used to treat benign prostatic hypertrophy in dogs weighing 10 to 50 kilograms.

DHT affects testicular development and regulates spermatogenesis in some fish.

Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.

Dihydrotestosterone boosts inflammation in fat cells more than testosterone.

Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

Dihydrotestosterone has a reduced effect on muscle-building in people with testicular feminization syndrome, especially after their gonads are removed.

Dutasteride and finasteride can help increase hair growth gene expression but need further improvement.

Adolescent male rats release more stress hormones than adults, and testosterone affects them differently.

DHT may increase the risk of heart disease and death in elderly men.

New genes and pathways are important for testosterone production and male sexual development.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Dihydrotestosterone can be made from dehydroepiandrosterone in skin cells without needing testosterone.

Pueraria mirifica extract may help treat benign prostatic hyperplasia.

Testosterone increases muscle mass regardless of DHT conversion blocking.

Heart-specific steroid metabolism is crucial in cardiac hypertrophy.

Increased DHT formation in skin can cause hair loss, acne, and excessive hair growth, and antiandrogens might treat these conditions.

Finasteride reduces scalp DHT levels, potentially treating male pattern baldness.

Testosterone boosts red blood cell production and changes iron metabolism without needing dihydrotestosterone.

Testosterone needs to be converted to DHT to reduce stress response in male rats.