research Effects of finasteride on expression of vascular endothelial growth factor and microvascular density in retina of early diabetic rats
Finasteride reduces VEGF expression and microvascular growth in diabetic rat retinas.
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840-870 / 1000+ resultsresearch Nanoclay gels promote re-epithelialization and improve the quality of skin wound healing in a diabetic mouse model
Nanoclay gels improve skin wound healing quality in diabetic mice.
research 74126 GLP-1RA Medications and Alopecia: Evaluating Risk Across Diabetic and Non-Diabetic Populations
GLP-1RA medications may increase the risk of hair loss, especially in non-diabetic people.
research Do finasteride and bicalutamide affect blood glucose levels in diabetics?
Finasteride and bicalutamide can affect blood sugar, so diabetics need monitoring.
research Do finasteride and bicalutamide affect blood glucose levels in diabetics?
Finasteride and bicalutamide can affect blood sugar, so diabetics need monitoring.
research Synergistic Antioxidant-Antimicrobial-Immunomodulatory Self-Healing “Radical Sponge” Hydrogel for Diabetic Wound Regeneration via Microenvironment Reprogramming Mediated by Coordinated MAPK Suppression and PI3K-AKT Activation
research Synergistic Antioxidant-Antimicrobial-Immunomodulatory Self-Healing “Radical Sponge” Hydrogel for Diabetic Wound Regeneration via Microenvironment Reprogramming Mediated by Coordinated MAPK Suppression and PI3K-AKT Activation
research Synergistic Antioxidant-Antimicrobial-Immunomodulatory Self-Healing “Radical Sponge” Hydrogel for Diabetic Wound Regeneration via Microenvironment Reprogramming Mediated by Coordinated MAPK Suppression and PI3K-AKT Activation
research Elastogenesis Stimulation by Minoxidil or Nebivolol Reduces Premature Aging of the Aortic Wall in Diabetic Mice
Minoxidil and nebivolol can help prevent aortic aging in diabetic mice.
research Facile strategy for gelatin-based hydrogel with multifunctionalities to remodel wound microenvironment and accelerate healing of acute and diabetic wounds
The gelatin-based hydrogel helps heal acute and diabetic wounds faster by improving healing conditions.
research Effects of finasteride on microvascular density and VEGF expression in glomeruli of diabetic mice
Finasteride reduced VEGF expression and microvascular density in diabetic mice.
research Hyperandrogenemia in an ethnically heterogeneous cohort of Midwestern United States diabetic gestations
Exposure to fatty acids significantly increased androgen levels in female dogs, suggesting a link to conditions like insulin resistance and PCOS.
research Human Wharton's Jelly Stem Cells and Its Conditioned Medium Enhance Healing of Excisional and Diabetic Wounds
Human Wharton's jelly stem cells improve wound healing.
research Dual-functional hybrid quaternized chitosan/Mg/alginate dressing with antibacterial and angiogenic potential for diabetic wound healing
The study evaluated a dual-functional dressing made from quaternized chitosan and magnesium for treating diabetic foot ulcers (DFUs). The dressing demonstrated significant antibacterial properties, effectively eradicating MRSA and MRSE, and promoted wound healing by facilitating the migration of human dermal fibroblasts and endothelial cells, as well as stimulating angiogenesis. In vivo tests on a diabetic rat model confirmed its anti-infection and wound-healing potential. The dressing showed promise for clinical application due to its ability to improve DFU treatment outcomes and its biocompatibility, addressing a critical need in managing this common diabetes complication.
research Silicone elastomer gel impregnated with 20(S)-protopanaxadiol-loaded nanostructured lipid carriers for ordered diabetic ulcer recovery
research Fibroblast Growth Factor-9 Activates c-Kit Progenitor Cells and Enhances Angiogenesis in the Infarcted Diabetic Heart
Fibroblast Growth Factor-9 helps repair heart damage after a heart attack by creating new blood vessels, especially in diabetics.
research Single-cell analysis reveals distinct functional heterogeneity of CD34+ cells in anagen wound and diabetic wound
This study investigated the functional heterogeneity of CD34+ cells in anagen and diabetic wounds using single-cell RNA sequencing. Researchers identified 10 cell clusters and 6 cell types, including endothelial cells, fibroblasts, and macrophages. In anagen wounds, CD34+ fibroblasts C2, associated with inflammation and extracellular matrix, were predominant. Diabetic wounds showed increased CD34+ endothelial cells, fibroblasts C4, and neutrophils, with decreased fibroblasts C1. Differentially expressed genes were analyzed to understand enriched pathways for each cell cluster. The findings provided insights into CD34+ cell roles in wound healing and suggested potential therapeutic approaches for treating wounds.
research Umbilical cord mesenchymal stem cell-derived apoptotic extracellular vesicles ameliorate cutaneous wound healing in type 2 diabetic mice via macrophage pyroptosis inhibition
Special particles from umbilical cord stem cells help heal skin wounds in diabetic mice by preventing certain immune cell death.
research Photocrosslinkable Chitosan Quaternary Ammonium Salt-Based Ternary Hydrogel with Fibroblast Growth Factor 21 for Diabetic Wound Healing
The study developed a photocrosslinkable chitosan quaternary ammonium salt-based ternary hydrogel, G/C-CS@FGF-21, to improve diabetic wound healing. This hydrogel combines fibroblast growth factor 21 (FGF-21) for inflammation resolution, chitosan for antimicrobial function, gelatin for mechanical resilience, and collagen for cell adhesion. In vitro, it promoted anti-inflammatory macrophage polarization and fibroblast activity. In diabetic mice, it accelerated wound closure by reducing inflammation and enhancing reepithelialization and angiogenesis. The findings indicate strong potential for clinical use in managing diabetic wounds.
research Formulation of Deformable Liponiosomal Hybrid of Repaglinide: In vitro Characterization and Evaluation of the Anti-Diabetic Effect
Repaglinide-loaded liponiosomal hybrids improve blood sugar control and insulin release better than regular Repaglinide.
research Clinical value of adipose tissue-derived stem cells application in healing of experimental diabetic and nondiabetic burn
Adipose tissue-derived stem cells effectively improve burn healing, especially in diabetics.
research An off-the-shelf bioactive EV delivering cryogel orchestrating immunomodulatory reprogramming and angiogenesis for diabetic ulcer healing
BOOST is a promising, easy-to-use treatment for diabetic foot ulcers that improves healing by reducing inflammation and promoting blood vessel growth.
research The combination of Virgin Coconut Oil (VCO) and Nigella sativa Oil (NSO) in wound healing: A histochemical study of diabetic wounds
Combining Virgin Coconut Oil and Nigella Sativa Oil speeds up healing in diabetic wounds.
research Photo-Crosslinked and Photothermal Flammulina Velutipes Polysaccharide Hydrogel Loaded with Caffeic Acid-Copper Nanozyme for Diabetic Wound Healing
research Lethal dose Examination and Effect of Different Part Extracts of Ageratum conyzoides L on Hematology and Serum Electrolytes of Streptozotocin Induce Diabetic Rats
Ageratum conyzoides may lower blood sugar and improve blood lipid levels in diabetic rats.
research 290 Efficacy of Low-Intensity Shock Wave Therapy for the Treatment of ED in Diabetic Patients : A Pooled Analysis
Low-intensity shock wave therapy is effective in treating erectile dysfunction in diabetic patients.
research 1431 Neutralizing α-toxin accelerates healing of Staphylococcus aureus-infected wounds in normal and diabetic mice
Blocking α-toxin helps heal Staphylococcus aureus-infected wounds faster in both normal and diabetic mice, with different effects on their immune responses.
research PSS38 USE OF CALL CENTRE METHODOLOGY TO COLLECT QUALITY OF LIFE (QOL) DATA IN A CLINICAL TRIAL: A CASE STUDY OF PATIENTS WITH DIABETIC MACULAR EDEMA (DME)
Using a call center to collect data in a trial for eye disease in diabetics led to high response rates and very little missing information.
research Synergistic Antibacterial Activity and Wound Healing Properties of Selenium-Chitosan-Mupirocin Nanohybrid System: An in Vivo Study on Rat Diabetic Staphylococcus aureus Wound Infection Model
The nanohybrid system significantly improved wound healing and showed strong antibacterial activity.
research Soy protein/β-chitin sponge-like scaffolds laden with human mesenchymal stromal cells from hair follicle or adipose tissue promote diabetic chronic wound healing
Sponges made of soy protein and β-chitin with human cells from hair or fat can speed up healing of chronic wounds.