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Nanoporous silica entrapped lipid-drug complexes significantly improve the solubility and absorption of drugs that don't dissolve well in water.

Farudodstat may effectively treat alopecia areata without harmful side effects.

Hexahydrobenzo[f]quinolines are effective at blocking the enzyme 5α-reductase.

Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

Sebum helps protect human skin from microbes.

Baricitinib helps regrow hair in adults with severe alopecia better than a placebo and is approved for treatment, but long-term effects are still unknown.

Ceramide helps protect African–American hair from breakage.

Cyproterone acetate improves skin symptoms and quality of life in women with androgen-related issues.

Home-use treatment for severe alopecia areata is as effective as office-use but costs half as much.

The document concludes that biotin, folate, and RGD peptides are promising for targeting cancer cells with prodrugs, but the conjugates are not yet tested for use.

Removing part of the vitamin D receptor stops vitamin D from working properly.

Ursolic acid can shrink the prostate and lower a hormone linked to prostate growth in rats.

Early diagnosis and proper treatment improve outcomes for methylmalonic acidemia.

New probes were created to effectively measure specific enzymes involved in fat metabolism, which could help develop new drugs.

Cronkhite-Canada syndrome causes chronic diarrhea and has a poor prognosis despite treatment.

Hyaluronic acid successfully treated skin atrophy caused by corticosteroid injections.

Researchers developed new compounds that target the androgen receptor effectively with fewer side effects.

Glycyrrhizic acid may help reduce unwanted hair growth.

Asparagus racemosus root extract reduced sebum and pore size in men but not in women.

Clascoterone may be an effective topical treatment for hair loss.

Clascoterone cream could be used for other skin conditions affected by hormones.

N-oxides are important in medicine for improving drug properties and targeting.

A new liposomal system for applying dutasteride to the skin was developed, showing better skin absorption and stability, potentially improving treatment for hair loss.

The gel is a safe and effective treatment for hyperpigmentation.

Researchers created a reliable method to measure dexpanthenol and resorcinol in hair products.

Dihydroartemisinin could be a versatile cosmetic ingredient but needs more research and development.

A substance called poly(I:C) increases a protein called carbonic anhydrase II in skin cells, which might help with skin defense and healing.