38 citations
,
June 2018 in “Archives of Toxicology” Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
28 citations
,
January 1991 in “Reproductive Toxicology” Finasteride temporarily lowers male rat fertility without affecting libido.
25 citations
,
March 2017 in “Archives of Dermatological Research” Sinapic acid may help hair growth by activating a specific cell pathway.
24 citations
,
March 2001 in “Journal of Endocrinology/Journal of endocrinology” Red deer only have androgen receptors in neck hair cells for mane growth during breeding season.
23 citations
,
January 2001 in “International journal of toxicology” St. John's Wort extract and oil safety in cosmetics is unclear; more data needed on photosensitization, toxicity, and human irritation.
22 citations
,
November 2016 in “Indian Journal of Pharmaceutical Education and Research” Hibiscus rosa-sinensis leaf extract is safe, has strong antioxidants, and effectively heals wounds.
21 citations
,
July 2014 in “Antimicrobial Agents and Chemotherapy” Finasteride effectively prevents biofilm formation and treats preformed biofilms, but requires high doses.
17 citations
,
June 2021 in “Molecules” Melatonin-loaded nanocarriers improve melatonin delivery and effectiveness for various medical treatments.
17 citations
,
May 1998 in “Steroids” Researchers developed a model to predict how well certain compounds can block an enzyme related to hair loss and prostate issues, suggesting a 50 mg dose of finasteride might be effective based on lab and body data.
15 citations
,
July 2019 in “Journal of Biological Inorganic Chemistry” Finasteride helps prevent kidney stones, but side effects need more research.
15 citations
,
August 2017 in “International Journal of Molecular Medicine” Panax ginseng extract may help prevent hair loss caused by DKK-1.
14 citations
,
April 2021 in “Biology” Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.
13 citations
,
December 2017 in “BMC Complementary and Alternative Medicine” The Asian herbal mix with Houttuynia cordata, Perilla frutescens, and green tea helped grow hair in mice.
13 citations
,
January 2017 in “Chemical & Pharmaceutical Bulletin” Certain compounds, especially those with a propionic substituent, could potentially be new treatments for hair loss and similar disorders.
10 citations
,
January 2003 in “Journal der Deutschen Dermatologischen Gesellschaft” Hydroxychloroquine helped improve scleromyxoedema in patients, but caused side effects in some.
8 citations
,
January 1996 in “Springer eBooks” Male pattern baldness may be caused by factors like poor blood circulation, scalp tension, stress, and hormonal imbalances, but the exact causes are still unclear.
7 citations
,
June 2021 in “Amino acids” Human hair protein modifications could potentially indicate heart disease risk.
7 citations
,
August 2019 in “Bioorganic & medicinal chemistry” Analog 23 is a promising compound for prostate cancer treatment.
6 citations
,
February 2023 in “Plant and Soil” Bacillus subtilis strain WM13-24 helps plant root growth through volatile compounds.
6 citations
,
March 2021 in “International Journal of Pharmaceutics” Optimal long-acting finasteride injection dose found: 16.8 mg, effective for one month.
6 citations
,
January 2013 in “Chemical & pharmaceutical bulletin/Chemical and pharmaceutical bulletin” A new compound shows promise as a topical treatment for hair loss.
5 citations
,
August 2018 in “Sexual Medicine Reviews” 5α-Reductase inhibitors do not consistently increase testosterone levels in the blood.
4 citations
,
May 2018 in “Electronic Journal of Biotechnology” All-trans retinoic acid at high doses harms goat hair growth cells and could be bad for hair growth.
4 citations
,
October 2017 in “Advances in tissue engineering & regenerative medicine” Researchers created a potential skin substitute using a biodegradable mat that supports skin cell growth and layer formation.
3 citations
,
January 2017 in “Yonsei Medical Journal” Blocking 11β-HSD1 can lessen the harmful effects of glucocorticoids on hair growth cells.
3 citations
,
January 2003 in “Synthetic Communications” Scientists made two new chemicals that might help treat diseases caused by male hormones.
1 citations
,
January 2025 in “American Journal of Translational Research” PPARα agonists may help treat alopecia areata by reducing inflammation.
1 citations
,
June 2007 in “Almustansiriya journal of pharmaceutical sciences/Al-Mustansiriyah journal of pharmaceutical sciences” Antioxidants can help improve hair growth in people with alopecia areata.
1 citations
,
January 2006 in “Elsevier eBooks” The conclusion is that different types of hair loss in dogs and cats can be cosmetic or serious, and affected animals should not be bred.
February 2026 in “Chinese Medicine” Natural products might help treat hair greying.