research A mutation in MAP2 is associated with prenatal hair follicle density
A mutation in the MAP2 gene causes reduced hair follicle density, leading to hairlessness.
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research Characterization and management of hypertrichosis induced by low-dose oral minoxidil in the treatment of hair loss
Low-dose oral minoxidil for hair loss can cause mild excessive hair growth, usually appearing within the first 3 months, but it can be managed by adjusting the dose or removing the unwanted hair, with most people not needing to stop the treatment.
research Gynostemma pentaphyllum Hydrodistillate and Damulin B Prevent UVB‐Induced Photoaging In Vitro and In Vivo via ROS Suppression and Restoration of MAPK/AP‐1 and TGF‐β/Smad Signaling
Gynostemma pentaphyllum and Damulin B help prevent skin aging from UVB by reducing oxidative stress and improving skin health.
research Direct hair growth promoting effects of mycophenolic acid
Mycophenolic acid may help hair grow by activating pathways important for hair growth.
research In vivo and in vitro effect of novel 4,16-pregnadiene-6,20-dione derivatives, as 5α-reductase inhibitors
The new compounds may be more effective and cheaper than current treatments for conditions like baldness.
research Patent Evaluation: Δ-4,6-Steroids as Potent 5α-Reductase Inhibitors
New steroids were patented as effective for treating acne, hair loss, and other conditions related to hormones.
research Perspectives on miRNAs Targeting DKK1 for Developing Hair Regeneration Therapy
Targeting a protein that blocks hair growth with microRNAs could lead to new hair loss treatments, but more research is needed.
research 0882 Patterning and regional specification of hairy skin
Secreted inhibitors of Wnt and IGF signaling control hair and tooth development, creating species-specific patterns.
research A study on effects of water-soluble minoxidil on hair growth in C57BL/6 mice
Water-soluble minoxidil effectively promoted hair growth in mice.
research Abstract 2474: The mechanistic role of polyamines in DNA double-strand break repair
Polyamines help repair DNA breaks and may influence cancer development.
research Trichothiodystrophy hair shafts display distinct ultrastructural features
Trichothiodystrophy hair is structurally abnormal with protein and organization issues.
research 1360 Fate tracing of DNA-damaged hair follicle stem cells and their seno-differentiation clearance out of the niche
Damaged hair follicle stem cells may leave the skin to help maintain youthfulness.
research Dissolving microneedles for alopecia treatment
Dissolving microneedles show promise for treating hair loss but need more research for practical use.
research 755 Repurposing of DPP4 inhibition to improve hair follicle activation and regeneration
Blocking DPP4 can help activate hair growth and improve hair regeneration.
research Optimization of the method for the culture of melanocyte precursors from hair follicles and their activation by 1,25-dihydroxyvitamin D3
1,25-dihydroxyvitamin D3 helps melanocyte precursors from hair follicles grow and produce melanin, aiding vitiligo treatment understanding.
research MiR-23b and miR-133 Cotarget TGFβ2/NOTCH1 in Sheep Dermal Fibroblasts, Affecting Hair Follicle Development
MiR-23b and miR-133 affect sheep hair growth by targeting specific genes.
research Effect of minoxidil on proliferation and apoptosis in dermal papilla cells of human hair follicle
Minoxidil boosts hair growth by increasing cell production and survival.
research Characterization of Recombinant Human Liver Thermolabile Phenol Sulfotransferase with Minoxidil as the Substrate
Both enzyme forms can sulfate minoxidil.
research Aberrant Activation of the Hedgehog Pathway in Cutaneous Melanoma: Therapeutic Potential of Pharmacological Inhibitors
Hedgehog pathway inhibitors could be effective in treating melanoma.
research Integrative Proteo‐Transcriptomic Characterization of Androgenetic Alopecia Identifying ME1 ‐Mediated PPAR Signaling as a Potential Mediator
ME1 and PPAR signaling may influence hair loss in androgenetic alopecia.
research MCPIP1 controls effects of myeloid cells on skin carcinogenesis and hair growth
MCPIP1 in myeloid cells is important for skin cancer development and healthy hair growth.
research Transcriptome Analysis Reveals an Inhibitory Effect of Dihydrotestosterone-Treated 2D- and 3D-Cultured Dermal Papilla Cells on Hair Follicle Growth
Dihydrotestosterone treatment on 2D and 3D-cultured skin cells slows down hair growth by affecting certain genes and could be a potential target for hair loss treatment.
research Value of dermoscopy for the diagnosis of monilethrix
Dermoscopy helped diagnose a rare hair disorder in a 2-year-old boy.
research Meloside A Protects Dermal Papilla Cells from DHT-Induced Damage via Androgen Receptor Modulation
Meloside A may help protect hair cells from damage linked to hair loss.
research Microemulsions as Solubilizers and Penetration Enhancers for Minoxidil Release from Gels
Microemulsions can improve minoxidil delivery and effectiveness for hair loss treatment.
research 11β-Hydroxylase inhibitors protect against seizures in mice by increasing endogenous neurosteroid synthesis
11β-Hydroxylase inhibitors help prevent seizures in mice by boosting natural neurosteroid production.
research The influence of methotrexate on hair loss while using immunomodulatory doses.
Methotrexate treatment often causes hair loss.
research Enhancement of Dermal Delivery of Finasteride Using MicroemulsionSystems
Microemulsions can improve skin delivery of finasteride.
research 3,3-Diphenylpentane skeleton as a steroid skeleton substitute: Novel inhibitors of human 5α-reductase 1
A new compound effectively inhibits human 5α-reductase 1.
research Cross‐linked features of mouse pelage hair resistant to detergent extraction
Two mouse mutants have defective hair cuticle cross-linking.